Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis von Schafer, PH, Parton, A, Gandhi, AK, Capone, L, Adams, M, Wu, L, Bartlett, JB, Loveland, MA, Gilhar, A, Cheung, Y‐F, Baillie, GS, Houslay, MD, Man, H‐W, Muller, GW, Stirling, DI

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Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications von GUPTA, D, TREON, S. P, SCHLOSSMAN, R. L, RICHARDSON, P, RALPH, P, WU, L, PAYVANDI, F, MULLER, G, STIRLING, D. I, ANDERSON, K. C, SHIMA, Y, HIDESHIMA, T, PODAR, K, TAI, Y. T, LIN, B, LENTZSCH, S, DAVIES, F. E, CHAUHAN, D

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Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy von Hideshima, Teru, Chauhan, Dharminder, Shima, Yoshihito, Raje, Noopur, Davies, Faith E., Tai, Yu-Tzu, Treon, Steven P., Lin, Boris, Schlossman, Robert L., Richardson, Paul, Muller, George, Stirling, David I., Anderson, Kenneth C.

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Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma von Raje, Noopur, Kumar, Shaji, Hideshima, Teru, Ishitsuka, Kenji, Chauhan, Dharminder, Mitsiades, Constantine, Podar, Klaus, Le Gouill, Steven, Richardson, Paul, Munshi, Nikhil C., Stirling, David I., Antin, Joseph H., Anderson, Kenneth C.

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Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha von Corral, L G, Haslett, P A, Muller, G W, Chen, R, Wong, L M, Ocampo, C J, Patterson, R T, Stirling, D I, Kaplan, G

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Thalidomide as a novel therapeutic agent: new uses for an old product von Teo, Steve K., Stirling, David I., Zeldis, Jerome B.

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Immunomodulatory analogs of thalidomide inhibit growth of Hs sultan cells and angiogenesis in vivo von LENTZSCH, S, LEBLANC, R, POCLAR, K, DAVIES, F, LIN, B, HIDESHIMA, T, CATLEY, L, STIRLING, D. I, ANDERSON, K. C

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Protective Antitumor Immunity Induced by a Costimulatory Thalidomide Analog in Conjunction with Whole Tumor Cell Vaccination Is Mediated by Increased Th1-Type Immunity von Dredge, Keith, Marriott, J. Blake, Todryk, Stephen M, Muller, George W, Chen, Roger, Stirling, David I, Dalgleish, Angus G

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Clinical pharmacokinetics of thalidomide von TEO, Steve K, COLBURN, Wayne A, TRACEWELL, William G, KOOK, Karin A, STIRLIN, David I, JAWORSKY, Markian S, SCHEFFLER, Michael A, THOMAS, Steve D, LASKIN, Oscar L

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Thalidomide in the treatment of leprosy von Teo, Steve K., Resztak, Ken E., Scheffler, Michael A., Kook, Karin A., Zeldis, Jerry B., Stirling, David I., Thomas, Steve D.

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Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity von Schafer, P.H., Parton, A., Capone, L., Cedzik, D., Brady, H., Evans, J.F., Man, H.-W., Muller, G.W., Stirling, D.I., Chopra, R.

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Effects of Thalidomide on Developmental, Peri- and Postnatal Function in Female New Zealand White Rabbits and Offspring von Teo, Steve K., Denny, Kevin H., Stirling, David I., Thomas, Steve D., Morseth, Sandy, Hoberman, Alan M.

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Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma von Davies, Faith E., Raje, Noopur, Hideshima, Teru, Lentzsch, Suzanne, Young, Gloria, Tai, Yu-Tzu, Lin, Boris, Podar, Klaus, Gupta, Deepak, Chauhan, Dharminder, Treon, Steven P., Richardson, Paul G., Schlossman, Robert L., Morgan, Gareth J., Muller, George W., Stirling, David I., Anderson, Kenneth C.

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Thalidomide analogs and PDE4 inhibition von Muller, George W., Shire, Mary G., Wong, Lu Min, Corral, Laura G., Patterson, Rebecca T., Chen, Yuxi, Stirling, David I.

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Chiral inversion of the second generation IMiD™ CC-4047 (ACTIMID™) in human plasma and phosphate-buffered saline von Teo, Steve K., Chen, Yong, Muller, George W., Chen, Roger S., D. Thomas, Steve, Stirling, David I., Chandula, Reddy S.

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Thalidomide Dose Proportionality Assessment following Single Doses to Healthy Subjects von Teo, Steve K., Scheffler, Michael R., Kook, Karin A., Tracewell, William G., Colburn, Wayne A., Stirling, David I., Thomas, Steve D.

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Safety profile of thalidomide after 53 weeks of oral administration in beagle dogs von TEO, Steve K, EVANS, Mark G, BROCKMAN, Mark J, EHRHART, Julie, MORGAN, J. Michael, STIRLING, David I, THOMAS, Steve D

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Protein Homeostatic Modulators, a Novel Class of Cereblon-Targeting Small Molecules As Potential Clinical Candidates in Multiple Myeloma von Zou, Jianxuan, Jones, Richard J., Mertz, Janet E., Wang, Hua, Kuiatse, Isere, Sullivan, Bob, Fung, Leah, Richard, Normand, Erdman, Paul, Torres, Eduardo, Chourasia, Aparajita Hoskote, Chan, Kyle WH, Mercurio, Frank, Stirling, David I, Orlowski, Robert Z.

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Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced... von BARTLETT, J. B, MICHAE, A, ZELDIS, J, DALGLEISH, A. G, CLARKE, I. A, DREDGE, K, NICHOLSON, S, KRISTELEIT, H, POLYCHRONIS, A, PANDHA, H, MULLER, G. W, STIRLING, Dl

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Effects of thalidomide on reproductive function and early embryonic development in male and female New Zealand white rabbits von Teo, Steve K., Denny, Kevin H., Stirling, David I., Thomas, Steve D., Morseth, Sandra L., Hoberman, Alan M.

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