Editorial: Etiopathogenesis of Systemic Sclerosis: An Update von Stifano, Giuseppina, De Palma, Raffaele

Volltext

Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial von Khanna, Dinesh, Prof, Denton, Christopher P, Prof, Jahreis, Angelika, MD, van Laar, Jacob M, Prof, Frech, Tracy M, MD, Anderson, Marina E, FRCP, Baron, Murray, MD, Chung, Lorinda, MD, Fierlbeck, Gerhard, MD, Lakshminarayanan, Santhanam, MD, Allanore, Yannick, Prof, Pope, Janet E, MD, Riemekasten, Gabriela, Prof, Steen, Virginia, Prof, Müller-Ladner, Ulf, Prof, Lafyatis, Robert, MD, Stifano, Giuseppina, MD, Spotswood, Helen, PhD, Chen-Harris, Haiyin, PhD, Dziadek, Sebastian, PhD, Morimoto, Alyssa, PhD, Sornasse, Thierry, PhD, Siegel, Jeffrey, MD, Furst, Daniel E, Prof

Volltext

Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin von Apostolidis, Sokratis A, Stifano, Giuseppina, Tabib, Tracy, Rice, Lisa M, Morse, Christina M, Kahaleh, Bashar, Lafyatis, Robert

Volltext

Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis von Stifano, Giuseppina, Affandi, Alsya J, Mathes, Allison L, Rice, Lisa M, Nakerakanti, Sashidhar, Nazari, Banafsheh, Lee, Jungeun, Christmann, Romy B, Lafyatis, Robert

Volltext

A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin von Rice, Lisa M., Mantero, Julio C., Stifano, Giuseppina, Ziemek, Jessica, Simms, Robert W., Gordon, Jessica, Domsic, Robyn, Lafyatis, Robert

Volltext

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature von Feola, Aldo, Stifano, Giuseppina, Didona, Dario, Granata, Guido, Granata, Massimo

Volltext

Macrophage Involvement in Systemic Sclerosis: Do We Need More Evidence? von Stifano, Giuseppina, Christmann, Romy Beatriz

Volltext

The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments von Grieshaber-Bouyer, Ricardo, Radtke, Felix A., Cunin, Pierre, Stifano, Giuseppina, Levescot, Anaïs, Vijaykumar, Brinda, Nelson-Maney, Nathan, Blaustein, Rachel B., Monach, Paul A., Nigrovic, Peter A.

Volltext

Association of Interferon‐ and Transforming Growth Factor β–Regulated Genes and Macrophage Activation With Systemic Sclerosis–Related Progressive Lung Fibrosis von Christmann, Romy B., Sampaio‐Barros, Percival, Stifano, Giuseppina, Borges, Claudia L., Carvalho, Carlos R., Kairalla, Ronaldo, Parra, Edwin R., Spira, Avrum, Simms, Robert, Capellozzi, Vera L., Lafyatis, Robert

Volltext

Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis von van Bon, Lenny, Affandi, Alsya J, Broen, Jasper, Christmann, Romy B, Marijnissen, Renoud J, Stawski, Lukasz, Farina, Giuseppina A, Stifano, Giuseppina, Mathes, Allison L, Cossu, Marta, York, Michael, Collins, Cindy, Wenink, Mark, Huijbens, Richard, Hesselstrand, Roger, Saxne, Tore, DiMarzio, Mike, Wuttge, Dirk, Agarwal, Sandeep K, Reveille, John D, Assassi, Shervin, Mayes, Maureen, Deng, Yanhui, Drenth, Joost P.H, de Graaf, Jacqueline, den Heijer, Martin, Kallenberg, Cees G.M, Bijl, Marc, Loof, Arnoud, van den Berg, Wim B, Joosten, Leo A.B, Smith, Vanessa, de Keyser, Filip, Scorza, Rafaella, Lunardi, Claudio, van Riel, Piet L.C.M, Vonk, Madelon, van Heerde, Waander, Meller, Stephan, Homey, Bernhard, Beretta, Lorenzo, Roest, Mark, Trojanowska, Maria, Lafyatis, Robert, Radstake, Timothy R.D.J

Volltext

Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis von Stifano, Giuseppina, Sornasse, Thierry, Rice, Lisa M., Na, Leo, Chen‐Harris, Haiyin, Khanna, Dinesh, Jahreis, Angelika, Zhang, Yuqing, Siegel, Jeff, Lafyatis, Robert

Volltext

A Longitudinal Biomarker for the Extent of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis von Rice, Lisa M., Ziemek, Jessica, Stratton, Eric A., McLaughlin, Sarah R., Padilla, Cristina M., Mathes, Allison L., Christmann, Romy B., Stifano, Giuseppina, Browning, Jeffrey L., Whitfield, Michael L., Spiera, Robert F., Gordon, Jessica K., Simms, Robert W., Zhang, Yuqing, Lafyatis, Robert

Volltext

CXCL4 drives fibrosis by promoting several key cellular and molecular processes von Affandi, Alsya J, Carvalheiro, Tiago, Ottria, Andrea, de Haan, Judith J, Brans, Maike A D, Brandt, Maarten M, Tieland, Ralph G, Lopes, Ana P, Fernández, Beatriz Malvar, Bekker, Cornelis P J, van der Linden, Maarten, Zimmermann, Maili, Giovannone, Barbara, Wichers, Catharina G K, Garcia, Samuel, de Kok, Michael, Stifano, Giuseppina, Xu, Yan Juan, Kowalska, M Anna, Waasdorp, Maaike, Cheng, Caroline, Gibbs, Susan, de Jager, Saskia C A, van Roon, Joel A G, Radstake, Timothy R D J, Marut, Wioleta

Volltext

miR-155 in the progression of lung fibrosis in systemic sclerosis von Christmann, Romy B, Wooten, Alicia, Sampaio-Barros, Percival, Borges, Claudia L, Carvalho, Carlos R R, Kairalla, Ronaldo A, Feghali-Bostwick, Carol, Ziemek, Jessica, Mei, Yu, Goummih, Salma, Tan, Jiangning, Alvarez, Diana, Kass, Daniel J, Rojas, Mauricio, de Mattos, Thiago Lemos, Parra, Edwin, Stifano, Giuseppina, Capelozzi, Vera L, Simms, Robert W, Lafyatis, Robert

Volltext

Local skin gene expression reflects both local and systemic skin disease in patients with systemic sclerosis von Rice, Lisa M, Stifano, Giuseppina, Ziemek, Jessica, Lafyatis, Robert

Volltext

Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90 von Nazari, Banafsheh, Rice, Lisa M, Stifano, Giuseppina, Barron, Alexander M.S, Wang, Yu M, Korndorf, Tess, Lee, Jungeun, Bhawan, Jag, Lafyatis, Robert, Browning, Jeffrey L

Volltext

Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin von Mathes, Allison L, Christmann, Romy B, Stifano, Giuseppina, Affandi, Alsya J, Radstake, Timothy R D J, Farina, G Alessandra, Padilla, Cristina, McLaughlin, Sarah, Lafyatis, Robert

Volltext

Randomised, double-blind, placebo-controlled trial of IL1-trap, rilonacept, in systemic sclerosis. A phase I/II biomarker trial von Mantero, Julio C, Kishore, Nina, Ziemek, Jessica, Stifano, Giuseppina, Zammitti, Christopher, Khanna, Dinesh, Gordon, Jessica K, Spiera, Robert, Zhang, Yuqing, Simms, Robert W, Lafyatis, Robert

Volltext

Evaluating the efficacy and safety of 6-week extended interval dosing of natalizumab via a prospective, controlled, randomized, open-label, rater-blinded phase 3b study (P3.2-095) von Campbell, Nolan, Cohen, Jeffrey, Wiendl, Heinz, Foley, John, Butzkueven, Helmut, Ryerson, Lana Zhovtis, Giovannoni, Gavin, Arnold, Douglas, Defer, Gilles, Killestein, Joep, Cutter, Gary, Ren, Zheng, Kasliwal, Rachna, Stifano, Giuseppina, Chang, Ih, Ho, Pei-Ran

Volltext

CpGB DNA activates dermal macrophages and highly recruits inflammatory monocytes into the skin (P5120) von Mathes, Allison, Christmann, Romy, Affandi, Alsya, Stifano, Giuseppina, Lafyatis, Robert

Volltext