Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells von Michaelis, M, Rothweiler, F, Barth, S, Cinatl, J, van Rikxoort, M, Löschmann, N, Voges, Y, Breitling, R, von Deimling, A, Rödel, F, Weber, K, Fehse, B, Mack, E, Stiewe, T, Doerr, H W, Speidel, D, Cinatl, J

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NFATc1 as a therapeutic target in FLT3-ITD-positive AML von Metzelder, S K, Michel, C, von Bonin, M, Rehberger, M, Hessmann, E, Inselmann, S, Solovey, M, Wang, Y, Sohlbach, K, Brendel, C, Stiewe, T, Charles, J, Ten Haaf, A, Ellenrieder, V, Neubauer, A, Gattenlöhner, S, Bornhäuser, M, Burchert, A

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Role of p73 in malignancy: tumor suppressor or oncogene? von Stiewe, T, Pützer, B M

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Role of the p53-homologue p73 in E2F1-induced apoptosis von Pützer, Brigitte M, Stiewe, Thorsten

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Monitoring the dynamics of clonal tumor evolution in vivo using secreted luciferases von Charles, J.P, Fuchs, J, Hefter, M, Vischedyk, J.B, Kleint, M, Vogiatzi, F, Nist, A, Timofeev, O, Wanzel, M, Stiewe, T

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Widespread epigenetic activation of ΔNp73 in small cell lung cancer causes vulnerability to Tip60-p400 inhibition von Nist, A, Krampitz, A.M, Schlereth, K, Mernberger, M, Moßner, M.C, Muley, T, Dammann, R, Stiewe, T

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Mutant p53 promotes tumor progression by the endoplasmic reticulum UDPase ENTPD5 von Vogiatzi, F, Brandt, D.T, Fuchs, J, Grikscheit, K, Timofeev, O, Nist, A, Mernberger, M, Grosse, R, Stiewe, T

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CRISPR-Cas9-based target validation for p53-reactivating model compounds von Wanzel, M, Vischedyk, J, Gittler, M, Gremke, N, Mernberger, M, Charles, J, Schneikert, J, Bretz, A.C, Nist, A, Stiewe, T

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C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity von Sauer, Markus, Bretz, Anne Catherine, Beinoraviciute-Kellner, Rasa, Beitzinger, Michaela, Burek, Christof, Rosenwald, Andreas, Harms, Gregory S, Stiewe, Thorsten

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Regulation of telomerase activity by the p53 family member p73 von BEITZINGER, M, OSWALD, C, BEINORAVICIUTE-KELLNER, R, STIEWE, T

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PO-233 Chemoresistant NSCLC cells are hypersensitive to metabolic drugs due to mTOR-mediated inhibition of autophagy von Wanzel, M, Gremke, N, Schmoll, L, Pagenstecher, A, Schneikert, J, Stiewe, T

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73: Parainflammation in cancer von Lasry, A, Hamza, H, Kadosh, E, Elyada, E, Pribluda, A, Alitalo, K, Stiewe, T, Oren, M, Pikarsky, E, Ben-Neriah, Y

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Increased ΔN-p73 expression in tumors by upregulation of the E2F1-regulated, TA-promoter-derived ΔN′-p73 transcript von Pützer, B M, Tuve, S, Tannapfel, A, Stiewe, T

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p73 in apoptosis von Stiewe, T, Pützer, B M

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Antitumor capacity of a dominant-negative RET proto-oncogene mutant in a medullary thyroid carcinoma model von DROSTEN, M, STIEWE, T, PÜTZER, B. M

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Therapeutic efficacy of E2F1 in pancreatic cancer correlates with TP73 induction von RÖDICKER, Florian, STIEWE, Thorsten, ZIMMERMANN, Sonja, PÜTZER, Brigitte M

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Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes von Pützer, Brigitte M., Stiewe, Thorsten, Rödicker, Florian, Schildgen, Oliver, Rühm, Stefan, Dirsch, Olaf, Fiedler, Melanie, Damen, Uta, Tennant, Bud, Scherer, Caren, Graham, Frank L., Roggendorf, Michael

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E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products von Pützer, B M, Stiewe, T, Parssanedjad, K, Rega, S, Esche, H

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792 CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective, skin hyperpigmentation von Chang, C., Ito, T., Stiewe, T., Wakamatsu, K., Ben-Neriah, Y.

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338 - Widespread epigenetic activation of ΔNp73 in small cell lung cancer causes vulnerability to Tip60-p400 inhibition von Nist, A., Krampitz, A.M., Schlereth, K., Mernberger, M., Moßner, M.C., Muley, T., Dammann, R., Stiewe, T.

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