Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells von Gado, Francesca, Ferrisi, Rebecca, Di Somma, Sarah, Napolitano, Fabiana, Mohamed, Kawthar A, Stevenson, Lesley A, Rapposelli, Simona, Saccomanni, Giuseppe, Portella, Giuseppe, Pertwee, Roger G, Laprairie, Robert B, Malfitano, Anna Maria, Manera, Clementina

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Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R) von Ferrisi, Rebecca, Gado, Francesca, Polini, Beatrice, Ricardi, Caterina, Mohamed, Kawthar A., Stevenson, Lesley A., Ortore, Gabriella, Rapposelli, Simona, Saccomanni, Giuseppe, Pertwee, Roger G., Laprairie, Robert B., Manera, Clementina, Chiellini, Grazia

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Allosteric Modulation of the Cannabinoid CB1 Receptor von Price, Martin R., Baillie, Gemma L., Thomas, Adèle, Stevenson, Lesley A., Easson, Morag, Goodwin, Richard, McLean, Adèle, McIntosh, Lorraine, Goodwin, Gillian, Walker, Glenn, Westwood, Paul, Marrs, Julia, Thomson, Fiona, Cowley, Phillip, Christopoulos, Arthur, Pertwee, Roger G., Ross, Ruth A.

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Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593 von Brandt, Asher L., Garai, Sumanta, Zagzoog, Ayat, Hurst, Dow P., Stevenson, Lesley A., Pertwee, Roger G., Imler, Gregory H., Reggio, Patricia H., Thakur, Ganesh A., Laprairie, Robert B.

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Indomethacin Enhances Type 1 Cannabinoid Receptor Signaling von Laprairie, Robert B., Mohamed, Kawthar A., Zagzoog, Ayat, Kelly, Melanie E. M., Stevenson, Lesley A., Pertwee, Roger, Denovan-Wright, Eileen M., Thakur, Ganesh A.

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Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief von Gado, Francesca, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Bertini, Simone, Cappelli, Elena, Digiacomo, Maria, Stevenson, Lesley A, Macchia, Marco, Tuccinardi, Tiziano, Ghelardini, Carla, Pertwee, Roger G, Manera, Clementina

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Identification of the First Synthetic Allosteric Modulator of the CB 2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief von Gado, Francesca, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Bertini, Simone, Cappelli, Elena, Digiacomo, Maria, Stevenson, Lesley A, Macchia, Marco, Tuccinardi, Tiziano, Ghelardini, Carla, Pertwee, Roger G, Manera, Clementina

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Agonist‐inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656 and AM630 von Ross, Ruth A, Brockie, Heather C, Stevenson, Lesley A, Murphy, Vicki L, Templeton, Fiona, Makriyannis, Alexandros, Pertwee, Roger G

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Cannabidiolic acid methyl ester, a stable synthetic analogue of cannabidiolic acid, can produce 5‐HT1A receptor‐mediated suppression of nausea and anxiety in rats von Pertwee, Roger G, Rock, Erin M, Guenther, Kelsey, Limebeer, Cheryl L, Stevenson, Lesley A, Haj, Christeene, Smoum, Reem, Parker, Linda A, Mechoulam, Raphael

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Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands von Gado, Francesca, Ferrisi, Rebecca, Polini, Beatrice, Mohamed, Kawthar A., Ricardi, Caterina, Lucarini, Elena, Carpi, Sara, Domenichini, Federica, Stevenson, Lesley A., Rapposelli, Simona, Saccomanni, Giuseppe, Nieri, Paola, Ortore, Gabriella, Pertwee, Roger G., Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Chiellini, Grazia, Laprairie, Robert B., Manera, Clementina

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CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators von Gado, Francesca, Ceni, Costanza, Ferrisi, Rebecca, Sbrana, Giulia, Stevenson, Lesley A., Macchia, Marco, Pertwee, Roger G., Bertini, Simone, Manera, Clementina, Ortore, Gabriella

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PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor von Meini, Serena, Gado, Francesca, Stevenson, Lesley A., Digiacomo, Maria, Saba, Alessandro, Codini, Simone, Macchia, Marco, Pertwee, Roger G., Bertini, Simone, Manera, Clementina

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Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor von Gado, Francesca, Mohamed, Kawthar A., Meini, Serena, Ferrisi, Rebecca, Bertini, Simone, Digiacomo, Maria, D’Andrea, Felicia, Stevenson, Lesley A., Laprairie, Robert B., Pertwee, Roger G., Manera, Clementina

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Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor von Laprairie, Robert B, Kulkarni, Pushkar M, Deschamps, Jeffrey R, Kelly, Melanie E. M, Janero, David R, Cascio, Maria G, Stevenson, Lesley A, Pertwee, Roger G, Kenakin, Terrence P, Denovan-Wright, Eileen M, Thakur, Ganesh A

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(R)-Methanandamide: A Chiral Novel Anandamide Possessing Higher Potency and Metabolic Stability von Abadji, Vasiliki, Lin, Sonyuan, Taha, Gihan, Griffin, Graeme, Stevenson, Lesley A, Pertwee, Roger G, Makriyannis, Alexandros

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Big conductance calcium‐activated potassium channel openers control spasticity without sedation von Baker, David, Pryce, Gareth, Visintin, Cristina, Sisay, Sofia, Bondarenko, Alexander I, Vanessa Ho, W S, Jackson, Samuel J, Williams, Thomas E, Al‐Izki, Sarah, Sevastou, Ioanna, Okuyama, Masahiro, Graier, Wolfgang F, Stevenson, Lesley A, Tanner, Carolyn, Ross, Ruth, Pertwee, Roger G, Henstridge, Christopher M, Irving, Andrew J, Schulman, Jesse, Powell, Keith, Baker, Mark D, Giovannoni, Gavin, Selwood, David L

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Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe von Laprairie, Robert B, Kulkarni, Abhijit R, Kulkarni, Pushkar M, Hurst, Dow P, Lynch, Diane, Reggio, Patricia H, Janero, David R, Pertwee, Roger G, Stevenson, Lesley A, Kelly, Melanie E. M, Denovan-Wright, Eileen M, Thakur, Ganesh A

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Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor von Devane, William A., Hanuš, Lumir, Breuer, Aviva, Pertwee, Roger G., Stevenson, Lesley A., Griffin, Graeme, Gibson, Dan, Mandelbaum, Asher, Etinger, Alexander, Mechoulam, Raphael

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Synthesis and Structure−Activity Relationships of Amide and Hydrazide Analogues of the Cannabinoid CB1 Receptor Antagonist N-(Piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl... von Francisco, Ma. Elena Y, Seltzman, Herbert H, Gilliam, Anne F, Mitchell, René A, Rider, Sharyl L, Pertwee, Roger G, Stevenson, Lesley A, Thomas, Brian F

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Exploring the Benzimidazole Ring as a Substitution for Indole in Cannabinoid Allosteric Modulators von Hernandez-Folgado, Laura, Stevenson, Lesley A., Morales, Paula, Gómez-Cañas, María, Pazos, María Ruth, Cascio, Maria Grazia, Jagerovic, Nadine, Elguero, José, Pertwee, Roger, Goya, Pilar

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