Nectin family of cell-adhesion molecules: structural and molecular aspects of function and specificity von Samanta, Dibyendu, Almo, Steven C

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Recent advances in mammalian protein production von Bandaranayake, Ashok D., Almo, Steven C.

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Durable antitumor responses to CD47 blockade require adaptive immune stimulation von Sockolosky, Jonathan T., Dougan, Michael, Ingram, Jessica R., Ho, Chia Chi M., Kauke, Monique J., Almo, Steven C., Ploegh, Hidde L., Garcia, K. Christopher

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A naturally occurring antiviral ribonucleotide encoded by the human genome von Gizzi, Anthony S., Grove, Tyler L., Arnold, Jamie J., Jose, Joyce, Jangra, Rohit K., Garforth, Scott J., Du, Quan, Cahill, Sean M., Dulyaninova, Natalya G., Love, James D., Chandran, Kartik, Bresnick, Anne R., Cameron, Craig E., Almo, Steven C.

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Anti–CTLA-4 therapy requires an Fc domain for efficacy von Ingram, Jessica R., Blomberg, Olga S., Rashidian, Mohammad, Ali, Lestat, Garforth, Scott, Fedorov, Elena, Fedorov, Alexander A., Bonanno, Jeffrey B., Le Gall, Camille, Crowley, Stephanie, Espinosa, Camilo, Biary, Tamara, Keliher, Edmund J., Weissleder, Ralph, Almo, Steven C., Dougan, Stephanie K., Ploegh, Hidde L., Dougan, Michael

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Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab von Ramagopal, Udupi A., Liu, Weifeng, Garrett-Thomson, Sarah C., Bonanno, Jeffrey B., Yan, Qingrong, Srinivasan, Mohan, Wong, Susan C., Bell, Alasdair, Mankikar, Shilpa, Rangan, Vangipuram S., Deshpande, Shrikant, Korman, Alan J., Almo, Steven C.

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Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex von Garrett-Thomson, Sarah C., Massimi, Aldo, Fedorov, Elena V., Bonanno, Jeffrey B., Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D., Love, James D., Garforth, Scott J., Guha, Chandan, Almo, Steven C.

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Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB von Esakova, Olga A., Grove, Tyler L., Yennawar, Neela H., Arcinas, Arthur J., Wang, Bo, Krebs, Carsten, Almo, Steven C., Booker, Squire J.

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Expression, Clinical Significance, and Receptor Identification of the Newest B7 Family Member HHLA2 Protein von Janakiram, Murali, Chinai, Jordan M, Fineberg, Susan, Fiser, Andras, Montagna, Cristina, Medavarapu, Ramadevi, Castano, Ekaterina, Jeon, Hyungjun, Ohaegbulam, Kim C, Zhao, Ruihua, Zhao, Aimin, Almo, Steven C, Sparano, Joseph A, Zang, Xingxing

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PD-L1 is an activation-independent marker of brown adipocytes von Ingram, Jessica R., Dougan, Michael, Rashidian, Mohammad, Knoll, Marko, Keliher, Edmund J., Garrett, Sarah, Garforth, Scott, Blomberg, Olga S., Espinosa, Camilo, Bhan, Atul, Almo, Steven C., Weissleder, Ralph, Lodish, Harvey, Dougan, Stephanie K., Ploegh, Hidde L.

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Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity von Ho, Meng-Chiao, Wilczek, Carola, Bonanno, Jeffrey B, Xing, Li, Seznec, Janina, Matsui, Tsutomu, Carter, Lester G, Onikubo, Takashi, Kumar, P Rajesh, Chan, Man K, Brenowitz, Michael, Cheng, R Holland, Reimer, Ulf, Almo, Steven C, Shechter, David

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Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere von Mashiyama, Susan T, Malabanan, M Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C, Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D, Stead, Mark, Toro, Rafael, Vetting, Matthew W, Almo, Steven C, Armstrong, Richard N, Babbitt, Patricia C

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Programmed death-1 (PD-1)–deficient mice are extraordinarily sensitive to tuberculosis von Lázár-Molnár, Eszter, Chen, Bing, Sweeney, Kari A., Wang, Emilie J., Liu, Weijun, Lin, Juan, Porcelli, Steven A., Almo, Steven C., Nathenson, Stanley G., Jacobs, William R.

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Computational Redesign of PD-1 Interface for PD-L1 Ligand Selectivity von Shrestha, Rojan, Garrett, Sarah C., Almo, Steven C., Fiser, Andras

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Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine von Ryu, Huijeong, Grove, Tyler L, Almo, Steven C, Kim, Jungwook

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Viperin Reveals Its True Function von Rivera-Serrano, Efraín E, Gizzi, Anthony S, Arnold, Jamie J, Grove, Tyler L, Almo, Steven C, Cameron, Craig E

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SARS-CoV-2 multi-antigen protein microarray for detailed characterization of antibody responses in COVID-19 patients von Celikgil, Alev, Massimi, Aldo B, Nakouzi, Antonio, Herrera, Natalia G, Morano, Nicholas C, Lee, James H, Yoon, Hyun Ah, Garforth, Scott J, Almo, Steven C

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Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication von Hsu, Jack Chun-Chieh, Laurent-Rolle, Maudry, Pawlak, Joanna B., Xia, Hongjie, Kunte, Amit, Hee, Jia Shee, Lim, Jaechul, Harris, Lawrence D., Wood, James M., Evans, Gary B., Shi, Pei-Yong, Grove, Tyler L., Almo, Steven C., Cresswell, Peter

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Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens von Yuan, Yifeng, Zallot, Rémi, Grove, Tyler L., Payan, Daniel J., Martin-Verstraete, Isabelle, Šepić, Sara, Balamkundu, Seetharamsingh, Neelakandan, Ramesh, Gadi, Vinod K., Liu, Chuan-Fa, Swairjo, Manal A., Dedon, Peter C., Almo, Steven C., Gerlt, John A., de Crécy-Lagard, Valérie

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HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160 von Liu, Weifeng, Chou, Ting-Fang, Garrett-Thomson, Sarah C., Seo, Goo-Young, Fedorov, Elena, Ramagopal, Udupi A., Bonanno, Jeffrey B., Wang, Qingyang, Kim, Kenneth, Garforth, Scott J., Kakugawa, Kiyokazu, Cheroutre, Hilde, Kronenberg, Mitchell, Almo, Steven C.

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