Functional significance of the platelet immune receptors GPVI and CLEC-2 von Rayes, Julie, Watson, Steve P, Nieswandt, Bernhard

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Fibrin activates GPVI in human and mouse platelets von Alshehri, Osama M., Hughes, Craig E., Montague, Samantha, Watson, Stephanie K., Frampton, Jon, Bender, Markus, Watson, Steve P.

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The podoplanin-CLEC-2 axis inhibits inflammation in sepsis von Rayes, Julie, Lax, Siân, Wichaiyo, Surasak, Watson, Stephanie K., Di, Ying, Lombard, Stephanie, Grygielska, Beata, Smith, Stuart W., Skordilis, Kassiani, Watson, Steve P.

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Impact of the PI3-kinase/Akt pathway on ITAM and hemITAM receptors: Haemostasis, platelet activation and antithrombotic therapy von Moroi, Alyssa J., Watson, Steve P.

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Understanding Infection-Induced Thrombosis: Lessons Learned From Animal Models von Beristain-Covarrubias, Nonantzin, Perez-Toledo, Marisol, Thomas, Mark R, Henderson, Ian R, Watson, Steve P, Cunningham, Adam F

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Platelet-collagen interaction: is GPVI the central receptor? von Nieswandt, Bernhard, Watson, Steve P.

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The dual role of platelet‐innate immune cell interactions in thrombo‐inflammation von Rayes, Julie, Bourne, Joshua H., Brill, Alexander, Watson, Steve P.

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Low-dose Btk inhibitors selectively block platelet activation by CLEC-2 von Nicolson, Phillip L. R., Nock, Sophie H., Hinds, Joshua, Garcia-Quintanilla, Lourdes, Smith, Christopher W., Campos, Joana, Brill, Alexander, Pike, Jeremy A., Khan, Abdullah O., Poulter, Natalie S., Kavanagh, Deidre M., Watson, Stephani, Watson, Callum N., Clifford, Hayley, Huissoon, Aarnoud P., Pollitt, Alice Y., Eble, Johannes A., Pratt, Guy, Watson, Steve P., Hughes, Craig E.

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Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2 von Bourne, Joshua H., Colicchia, Martina, Di, Ying, Martin, Eleyna, Slater, Alexander, Roumenina, Lubka T., Dimitrov, Jordan D., Watson, Steve P., Rayes, Julie

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The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure von Chauhan, Abhishek, Sheriff, Lozan, Hussain, Mohammed T., Webb, Gwilym J., Patten, Daniel A., Shepherd, Emma L., Shaw, Robert, Weston, Christopher J., Haldar, Debashis, Bourke, Samuel, Bhandari, Rajan, Watson, Stephanie, Adams, David H., Watson, Steve P., Lalor, Patricia F.

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Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI von Nicolson, Phillip L R, Hughes, Craig E, Watson, Stephanie, Nock, Sophie H, Hardy, Alexander T, Watson, Callum N, Montague, Samantha J, Clifford, Hayley, Huissoon, Aarnoud P, Malcor, Jean-Daniel, Thomas, Mark R, Pollitt, Alice Y, Tomlinson, Michael G, Pratt, Guy, Watson, Steve P

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Immobilized fibrinogen activates human platelets through glycoprotein VI von Mangin, Pierre H, Onselaer, Marie-Blanche, Receveur, Nicolas, Le Lay, Nicolas, Hardy, Alexander T, Wilson, Clare, Sanchez, Ximena, Loyau, Stéphane, Dupuis, Arnaud, Babar, Amir K, Miller, Jeanette Lc, Philippou, Helen, Hughes, Craig E, Herr, Andrew B, Ariëns, Robert As, Mezzano, Diego, Jandrot-Perrus, Martine, Gachet, Christian, Watson, Steve P

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Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation von Chimen, Myriam, Evryviadou, Aigli, Box, Clare L, Harrison, Matthew J, Hazeldine, Jon, Dib, Lea H, Kuravi, Sahithi J, Payne, Holly, Price, Joshua M J, Kavanagh, Dean, Iqbal, Asif J, Lax, Sian, Kalia, Neena, Brill, Alex, Thomas, Steve G, Belli, Antonio, Crombie, Nicholas, Adams, Rachel A, Evans, Shelley-Ann, Deckmyn, Hans, Lord, Janet M, Harrison, Paul, Watson, Steve P, Nash, Gerard B, Rainger, G Ed

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The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent von Rayes, Julie, Jadoui, Soumaya, Lax, Siân, Gros, Angèle, Wichaiyo, Surasak, Ollivier, Véronique, Denis, Cécile V, Ware, Jerry, Nieswandt, Bernhard, Jandrot-Perrus, Martine, Watson, Steve P, Ho-Tin-Noé, Benoît

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Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice von Bender, Markus, May, Frauke, Lorenz, Viola, Thielmann, Ina, Hagedorn, Ina, Finney, Brenda A, Vögtle, Timo, Remer, Katharina, Braun, Attila, Bösl, Michael, Watson, Steve P, Nieswandt, Bernhard

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Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects von Johnson, Ben, Lowe, Gillian C, Futterer, Jane, Lordkipanidzé, Marie, MacDonald, David, Simpson, Michael A, Sanchez-Guiú, Isabel, Drake, Sian, Bem, Danai, Leo, Vincenzo, Fletcher, Sarah J, Dawood, Ban, Rivera, José, Allsup, David, Biss, Tina, Bolton-Maggs, Paula Hb, Collins, Peter, Curry, Nicola, Grimley, Charlotte, James, Beki, Makris, Mike, Motwani, Jayashree, Pavord, Sue, Talks, Katherine, Thachil, Jecko, Wilde, Jonathan, Williams, Mike, Harrison, Paul, Gissen, Paul, Mundell, Stuart, Mumford, Andrew, Daly, Martina E, Watson, Steve P, Morgan, Neil V

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Introducing high-throughput sequencing into mainstream genetic diagnosis practice in inherited platelet disorders von Bastida, José M, Lozano, María L, Benito, Rocío, Janusz, Kamila, Palma-Barqueros, Verónica, Del Rey, Mónica, Hernández-Sánchez, Jesús M, Riesco, Susana, Bermejo, Nuria, González-García, Hermenegildo, Rodriguez-Alén, Agustín, Aguilar, Carlos, Sevivas, Teresa, López-Fernández, María F, Marneth, Anna E, van der Reijden, Bert A, Morgan, Neil V, Watson, Steve P, Vicente, Vicente, Hernández-Rivas, Jesús M, Rivera, José, González-Porras, José R

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Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation von Mazharian, Alexandra, Ghevaert, Cedric, Zhang, Lin, Massberg, Steffen, Watson, Steve P.

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Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets von Hitchcock, Jessica R, Cook, Charlotte N, Bobat, Saeeda, Ross, Ewan A, Flores-Langarica, Adriana, Lowe, Kate L, Khan, Mahmood, Dominguez-Medina, C Coral, Lax, Sian, Carvalho-Gaspar, Manuela, Hubscher, Stefan, Rainger, G Ed, Cobbold, Mark, Buckley, Christopher D, Mitchell, Tim J, Mitchell, Andrea, Jones, Nick D, Van Rooijen, N, Kirchhofer, Daniel, Henderson, Ian R, Adams, David H, Watson, Steve P, Cunningham, Adam F

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Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development von Lowe, Kate L., Finney, Brenda A., Deppermann, Carsten, Hägerling, René, Gazit, Salomé L., Frampton, Jon, Buckley, Christopher, Camerer, Eric, Nieswandt, Bernhard, Kiefer, Friedemann, Watson, Steve P.

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