Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity von Dudhgaonkar, Shailesh, Ranade, Sourabh, Nagar, Jignesh, Subramani, Siva, Prasad, Durga Shiv, Karunanithi, Preethi, Srivastava, Ratika, Venkatesh, Kamala, Selvam, Sabariya, Krishnamurthy, Prasad, Mariappan, T Thanga, Saxena, Ajay, Fan, Li, Stetsko, Dawn K, Holloway, Deborah A, Li, Xin, Zhu, Jun, Yang, Wen-Pin, Ruepp, Stefan, Nair, Satheesh, Santella, Joseph, Duncia, John, Hynes, John, McIntyre, Kim W, Carman, Julie A

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A monovalent anti-human CD28 domain antibody antagonist: preclinical efficacy and safety von Suchard, Suzanne J, Davis, Patricia M, Kansal, Selena, Stetsko, Dawn K, Brosius, Ruth, Tamura, James, Schneeweis, Lumelle, Bryson, James, Salcedo, Theodora, Wang, Haiqing, Yang, Zheng, Fleener, Catherine A, Ignatovich, Olga, Plummer, Christopher, Grant, Steven, Nadler, Steven G

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2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses von Liu, Danya, Krummey, Scott M, Badell, I Raul, Wagener, Maylene, Schneeweis, Lumelle A, Stetsko, Dawn K, Suchard, Suzanne J, Nadler, Steven G, Ford, Mandy L

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Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction von Davis, Patricia M, Nadler, Steven G, Stetsko, Dawn K, Suchard, Suzanne J

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An LFA-1 ({alpha}L{beta}2) Small-Molecule Antagonist Reduces Inflammation and Joint Destruction in Murine Models of Arthritis von Suchard, Suzanne J, Stetsko, Dawn K, Davis, Patricia M, Skala, Stacey, Potin, Dominique, Launay, Michele, Dhar, T. G. Murali, Barrish, Joel C, Susulic, Vojkan, Shuster, David J, McIntyre, Kim W, McKinnon, Murray, Salter-Cid, Luisa

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Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-... von Watterson, Scott H, Xiao, Zili, Dodd, Dharmpal S, Tortolani, David R, Vaccaro, Wayne, Potin, Dominique, Launay, Michele, Stetsko, Dawn K, Skala, Stacey, Davis, Patric M, Lee, Deborah, Yang, Xiaoxia, McIntyre, Kim W, Balimane, Praveen, Patel, Karishma, Yang, Zheng, Marathe, Punit, Kadiyala, Pathanjali, Tebben, Andrew J, Sheriff, Steven, Chang, ChiehYing Y, Ziemba, Theresa, Zhang, Huiping, Chen, Bang-Chi, DelMonte, Albert J, Aranibar, Nelly, McKinnon, Murray, Barrish, Joel C, Suchard, Suzanne J, Murali Dhar, T. G

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Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold von DODD, Dharmpal S, SHERIFF, Steven, MCKINNON, Murray, BARRISH, Joel C, SUCHARD, Suzanne J, MURALI DHAR, T. G, CHANGE, Chiehying J, STETSKO, Dawn K, PHILLIPS, Linda M, YINGRU ZHANG, LAUNAY, Michele, POTIN, Dominique, VACCARO, Wayne, POSS, Michael A

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De novo design, synthesis, and in vitro activity of LFA-1 antagonists based on a bicyclic[5.5]hydantoin scaffold von Potin, Dominique, Launay, Michele, Nicolai, Eric, Fabreguette, Maud, Malabre, Patrice, Caussade, François, Besse, Dominique, Skala, Stacey, Stetsko, Dawn K., Todderud, Gordon, Beno, Brett R., Cheney, Daniel L., Chang, Chiehying J., Sheriff, Steven, Hollenbaugh, Diane L., Barrish, Joel C., Iwanowicz, Edwin J., Suchard, Suzanne J., Dhar, T.G. Murali

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Generation and characterization of a mouse LIGHT specific inhibitor in a murine model of colitis (THER4P.891) von Felix, Nathan, Kansal, Selena, Stetsko, Dawn, Yang, XiaoXia, Xie, Jenny, Suchard, Suzanne

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B cells from African American lupus patients exhibit an activated phenotype von Menard, Laurence C, Habte, Sium, Gonsiorek, Waldemar, Lee, Deborah, Banas, Dana, Holloway, Deborah A, Manjarrez-Orduno, Nataly, Cunningham, Mark, Stetsko, Dawn, Casano, Francesca, Kansal, Selena, Davis, Patricia M, Carman, Julie, Zhang, Clarence K, Abidi, Ferva, Furie, Richard, Nadler, Steven G, Suchard, Suzanne J

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Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101... von Potin, Dominique, Launay, Michele, Monatlik, Francoise, Malabre, Patrice, Fabreguettes, Maud, Fouquet, Andre, Maillet, Magali, Nicolai, Eric, Dorgeret, Loïc, Chevallier, François, Besse, Dominique, Dufort, Monique, Caussade, François, Ahmad, Syed Z, Stetsko, Dawn K, Skala, Stacey, Davis, Patricia M, Balimane, Praveen, Patel, Karishma, Yang, Zheng, Marathe, Punit, Postelneck, Jennifer, Townsend, Robert M, Goldfarb, Valentina, Sheriff, Steven, Einspahr, Howard, Kish, Kevin, Malley, Mary F, DiMarco, John D, Gougoutas, Jack Z, Kadiyala, Pathanjali, Cheney, Daniel L, Tejwani, Ravindra W, Murphy, Denette K, Mcintyre, Kim W, Yang, Xiaoxia, Chao, Sam, Leith, Leslie, Xiao, Zili, Mathur, Arvind, Chen, Bang-Chi, Wu, Daugh-Rurng, Traeger, Sarah C, McKinnon, Murray, Barrish, Joel C, Robl, Jeffrey A, Iwanowicz, Edwin J, Suchard, Suzanne J, Dhar, T. G. Murali

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Sa.32. The Impact of Abatacept on the Development of Disease in the K/BxN Model of Spontaneous Arthritis von Salter-Cid, Luisa, Santore, Marin, Shuster, David, Stetsko, Dawn, Suchard, Suzanne, Nadler, Steven

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IL-12 and IL-23 in health and disease von Stetsko, Dawn, Sauder, Daniel N

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Design of LFA-1 antagonists based on a 2,3-dihydro-1 H-pyrrolizin-5(7aH)-one scaffold von Dodd, Dharmpal S., Sheriff, Steven, Chang, ChiehYing J., Stetsko, Dawn K., Phillips, Linda M., Zhang, Yingru, Launay, Michele, Potin, Dominique, Vaccaro, Wayne, Poss, Michael A., McKinnon, Murray, Barrish, Joel C., Suchard, Suzanne J., Murali Dhar, T.G.

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Cellular basis for the species differences in sensitivity to cardiac glycosides (digitalis) von Gupta, Radhey S., Chopra, Arvind, Stetsko, Dawn K.

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Expression of mRNA Homologous to Interleukin 1 in Human Epidermal Cells von Bell, Tracy V., Harley, Calvin B., Stetsko, Dawn, Sauder, Daniel N.

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Biology and Molecular Biology of Epidermal Cell‐Derived Thymocyte Activating Factora von SAUDER, DANIEL N., ARSENAULT, TRACY, MCKENZIE, RODERICK c., STETSKO, DAWN K., HARLEY, CALVIN B.

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Inhibition of metabolic cooperation by phorbol esters in a cell culture system based on adenosine kinase deficient mutants of V79 cells von Gupta, Radhey S., Singh, Bhag, Stetsko, Dawn K.

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Biology and Molecular Biology of Epidermal Cell-Derived Thymocyte Activating Factor von SAUDER, DANIEL N., ARSENAULT, TRACY, MCKENZIE, RODERICK c., STETSKO, DAWN K., HARLEY, CALVIN B.

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