Adaptation in CRISPR-Cas Systems von Sternberg, Samuel H., Richter, Hagen, Charpentier, Emmanuelle, Qimron, Udi

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Expanding the Biologist’s Toolkit with CRISPR-Cas9 von Sternberg, Samuel H., Doudna, Jennifer A.

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 von Sternberg, Samuel H., Redding, Sy, Jinek, Martin, Greene, Eric C., Doudna, Jennifer A.

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Conformational control of DNA target cleavage by CRISPR–Cas9 von Sternberg, Samuel H., LaFrance, Benjamin, Kaplan, Matias, Doudna, Jennifer A.

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Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9 von Singh, Digvijay, Sternberg, Samuel H., Fei, Jingyi, Doudna, Jennifer A., Ha, Taekjip

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Enhanced proofreading governs CRISPR–Cas9 targeting accuracy von Chen, Janice S., Dagdas, Yavuz S., Kleinstiver, Benjamin P., Welch, Moira M., Sousa, Alexander A., Harrington, Lucas B., Sternberg, Samuel H., Joung, J. Keith, Yildiz, Ahmet, Doudna, Jennifer A.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System von Redding, Sy, Sternberg, Samuel H., Marshall, Myles, Gibb, Bryan, Bhat, Prashant, Guegler, Chantal K., Wiedenheft, Blake, Doudna, Jennifer A., Greene, Eric C.

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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation von Jinek, Martin, Jiang, Fuguo, Taylor, David W., Sternberg, Samuel H., Kaya, Emine, Ma, Enbo, Anders, Carolin, Hauer, Michael, Zhou, Kaihong, Lin, Steven, Kaplan, Matias, Iavarone, Anthony T., Charpentier, Emmanuelle, Nogales, Eva, Doudna, Jennifer A.

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Rational design of a split-Cas9 enzyme complex von Wright, Addison V., Sternberg, Samuel H., Taylor, David W., Staahl, Brett T., Bardales, Jorge A., Kornfeld, Jack E., Doudna, Jennifer A.

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Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases von Lampe, George D., King, Rebeca T., Halpin-Healy, Tyler S., Klompe, Sanne E., Hogan, Marcus I., Vo, Phuc Leo H., Tang, Stephen, Chavez, Alejandro, Sternberg, Samuel H.

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A prudent path forward for genomic engineering and germline gene modification von Baltimore, David, Berg, Paul, Botchan, Michael, Carroll, Dana, Charo, RAlta, Church, George, Corn, Jacob E, Daley, George Q, Doudna, Jennifer A, Fenner, Marsha, Greely, Henry T, Jinek, Martin, Martin, GSteven, Penhoet, Edward, Puck, Jennifer, Sternberg, Samuel H, Weissman, Jonathan S, Yamamoto, Keith R

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High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding von Boyle, Evan A., Andreasson, Johan O. L., Chircus, Lauren M., Sternberg, Samuel H., Wu, Michelle J., Guegler, Chantal K., Doudna, Jennifer A., Greenleaf, William J.

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CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference von Hochstrasser, Megan L., Taylor, David W., Bhata, Prashant, Guegler, Chantal K., Sternberg, Samuel H., Nogales, Eva, Doudna, Jennifer A.

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A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9 von Dagdas, Yavuz S, Chen, Janice S, Sternberg, Samuel H, Doudna, Jennifer A, Yildiz, Ahmet

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Mechanism of substrate selection by a highly specific CRISPR endoribonuclease von Sternberg, Samuel H, Haurwitz, Rachel E, Doudna, Jennifer A

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Novel molecular requirements for CRISPR RNA-guided transposition von Walker, Matt W G, Klompe, Sanne E, Zhang, Dennis J, Sternberg, Samuel H

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RNA-guided genetic silencing systems in bacteria and archaea von Wiedenheft, Blake, Sternberg, Samuel H., Doudna, Jennifer A.

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Substrate-Specific Kinetics of Dicer-Catalyzed RNA Processing von Chakravarthy, Srinivas, Sternberg, Samuel H., Kellenberger, Colleen A., Doudna, Jennifer A.

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Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing von Vo, Phuc Leo H., Acree, Christopher, Smith, Melissa L., Sternberg, Samuel H.

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Human parainfluenza virus 3 field strains undergo extracellular fusion protein cleavage to activate entry von Stearns, Kyle, Lampe, George, Hanan, Rachel, Marcink, Tara, Niewiesk, Stefan, Sternberg, Samuel H, Greninger, Alexander L, Porotto, Matteo, Moscona, Anne

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