Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia von Boyer, Cierra K., Bauchle, Casey J., Zhang, Jianchao, Wang, Yanzhuang, Stephens, Samuel B.

Volltext

SWELL1 is a glucose sensor regulating β-cell excitability and systemic glycaemia von Kang, Chen, Xie, Litao, Gunasekar, Susheel K., Mishra, Anil, Zhang, Yanhui, Pai, Saachi, Gao, Yiwen, Kumar, Ashutosh, Norris, Andrew W., Stephens, Samuel B., Sah, Rajan

Volltext

Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules von Parchure, Anup, Tian, Meng, Stalder, Danièle, Boyer, Cierra K, Bearrows, Shelby C, Rohli, Kristen E, Zhang, Jianchao, Rivera-Molina, Felix, Ramazanov, Bulat R, Mahata, Sushil K, Wang, Yanzhuang, Stephens, Samuel B, Gershlick, David C, von Blume, Julia

Volltext

Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival von Hayes, Heather L, Peterson, Brett S, Haldeman, Jonathan M, Newgard, Christopher B, Hohmeier, Hans E, Stephens, Samuel B

Volltext

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors von Tessem, Jeffery S., Moss, Larry G., Chao, Lily C., Arlotto, Michelle, Lu, Danhong, Jensen, Mette V., Stephens, Samuel B., Tontonoz, Peter, Hohmeier, Hans E., Newgard, Christopher B.

Volltext

The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis von Stephens, Samuel B., Edwards, Robert J., Sadahiro, Masato, Lin, Wei-Jye, Jiang, Cheng, Salton, Stephen R., Newgard, Christopher B.

Volltext

Nutrient Regulation of Pancreatic Islet β-Cell Secretory Capacity and Insulin Production von Rohli, Kristen E, Boyer, Cierra K, Blom, Sandra E, Stephens, Samuel B

Volltext

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function von Stephens, Samuel B., Schisler, Jonathan C., Hohmeier, Hans E., An, Jie, Sun, Albert Y., Pitt, Geoffrey S., Newgard, Christopher B.

Volltext

A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells von Li, Mark, Shao, Fan, Qian, Qingwen, Yu, Wenjie, Zhang, Zeyuan, Chen, Biyi, Su, Dan, Guo, Yuwei, Phan, An-Vi, Song, Long-sheng, Stephens, Samuel B., Sebag, Julien, Imai, Yumi, Yang, Ling, Cao, Huojun

Volltext

A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation von Hayes, Heather L., Zhang, Lu, Becker, Thomas C., Haldeman, Jonathan M., Stephens, Samuel B., Arlotto, Michelle, Moss, Larry G., Newgard, Christopher B., Hohmeier, Hans E.

Volltext

Utilization of commercial collagens for preparing well-differentiated human beta cells for confocal microscopy von Brennecke, Brianna R, Yang, USeong, Liu, Siming, Ilerisoy, Fatma S, Ilerisoy, Beyza N, Joglekar, Aditya, Kim, Lucy B, Peachee, Spencer J, Richtsmeier, Syreine L, Stephens, Samuel B, Sander, Edward A, Strack, Stefan, Moninger, Thomas O, Ankrum, James A, Imai, Yumi

Volltext

Divergent regulation of protein synthesis in the cytosol and endoplasmic reticulum compartments of mammalian cells von Stephens, Samuel B, Nicchitta, Christopher V

Volltext

Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation von Sue, Nancy, Thai, Le May, Saito, Atsushi, Boyer, Cierra K, Fordham, Ashleigh M, Yan, Chenxu, Davenport, Aimee, Tao, Jiang, Bensellam, Mohammed, Cantley, James, Shi, Yan-Chuan, Stephens, Samuel B, Imaizumi, Kazunori, Biden, Trevor J

Volltext

Defining Cytokine Responsive and Non-responsive human β-cells von Stephens, Samuel B

Volltext

Strain-Ecotype Specificity in Sinorhizobium meliloti-Medicago truncatula Symbiosis Is Correlated to Succinoglycan Oligosaccharide Structure von Simsek, Senay, Ojanen-Reuhs, Tuula, Stephens, Samuel B, Reuhs, Bradley L

Volltext

The Insulinostatic Effect of Ghrelin Requires MRAP2 Expression in δ Cells von Yin, Terry C., Bauchle, Casey J., Rouault, Alix A.J., Stephens, Samuel B., Sebag, Julien A.

Volltext

Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells von Bearrows, Shelby C, Bauchle, Casey J, Becker, McKenzie, Haldeman, Jonathan M, Swaminathan, Svetha, Stephens, Samuel B

Volltext

RABL6A Promotes Pancreatic Neuroendocrine Tumor Angiogenesis and Progression In Vivo von Maharjan, Chandra K., Umesalma, Shaikamjad, Kaemmer, Courtney A., Muniz, Viviane P., Bauchle, Casey, Mott, Sarah L., Zamba, K. D., Breheny, Patrick, Leidinger, Mariah R., Darbro, Benjamin W., Stephens, Samuel B., Meyerholz, David K., Quelle, Dawn E.

Volltext

Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation von Stephens, Samuel B, Dodd, Rebecca D, Brewer, Joseph W, Lager, Patrick J, Keene, Jack D, Nicchitta, Christopher V

Volltext

Mitochondrial Efflux of Citrate and Isocitrate Is Fully Dispensable for Glucose-Stimulated Insulin Secretion and Pancreatic Islet beta-Cell Function von Bauchle, Casey J., Rohli, Kristen E., Boyer, Cierra K., Pal, Vidhant, Rocheleau, Jonathan V., Liu, Siming, Imai, Yumi, Taylor, Eric B., Stephens, Samuel B.

Volltext