Measuring the activity of protein variants on a large scale using deep mutational scanning von Fowler, Douglas M, Stephany, Jason J, Fields, Stanley

Volltext

A higher order PUF complex is central to regulation of C. elegans germline stem cells von Qiu, Chen, Crittenden, Sarah L., Carrick, Brian H., Dillard, Lucas B., Costa Dos Santos, Stephany J., Dandey, Venkata P., Dutcher, Robert C., Viverette, Elizabeth G., Wine, Robert N., Woodworth, Jennifer, Campbell, Zachary T., Wickens, Marvin, Borgnia, Mario J., Kimble, Judith, Hall, Traci M. Tanaka

Volltext

LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells von Ferdous, Ahlan S., Lynch, Tina R., Costa Dos Santos, Stephany J., Kapadia, Deep H., Crittenden, Sarah L., Kimble, Judith

Volltext

High-resolution mapping of protein sequence-function relationships von Fowler, Douglas M, Araya, Carlos L, Fleishman, Sarel J, Kellogg, Elizabeth H, Stephany, Jason J, Baker, David, Fields, Stanley

Volltext

Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs von Rose, John C., Popp, Nicholas A., Richardson, Christopher D., Stephany, Jason J., Mathieu, Julie, Wei, Cindy T., Corn, Jacob E., Maly, Dustin J., Fowler, Douglas M.

Volltext

The in vivo functional significance of PUF hub partnerships in C. elegans germline stem cells von Ferdous, Ahlan S, Costa Dos Santos, Stephany J, Kanzler, Charlotte R, Shin, Heaji, Carrick, Brian H, Crittenden, Sarah L, Wickens, Marvin, Kimble, Judith

Volltext

Correction to: Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance von Veuger, Stephany J., Hunter, Jill E., Durkacz, Barbara W.

Volltext

High‐throughput, microscope‐based sorting to dissect cellular heterogeneity von Hasle, Nicholas, Cooke, Anthony, Srivatsan, Sanjay, Huang, Heather, Stephany, Jason J, Krieger, Zachary, Jackson, Dana, Tang, Weiliang, Pendyala, Sriram, Monnat, Raymond J, Trapnell, Cole, Hatch, Emily M, Fowler, Douglas M

Volltext

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact von Chiasson, Melissa A, Rollins, Nathan J, Stephany, Jason J, Sitko, Katherine A, Matreyek, Kenneth A, Verby, Marta, Sun, Song, Roth, Frederick P, DeSloover, Daniel, Marks, Debora S, Rettie, Allan E, Fowler, Douglas M

Volltext

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers von Matreyek, Kenneth A, Stephany, Jason J, Ahler, Ethan, Fowler, Douglas M

Volltext

In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity von Wise, Megan C, Xu, Ziyang, Tello-Ruiz, Edgar, Beck, Charles, Trautz, Aspen, Patel, Ami, Elliott, Sarah Tc, Chokkalingam, Neethu, Kim, Sophie, Kerkau, Melissa G, Muthumani, Kar, Jiang, Jingjing, Fisher, Paul D, Ramos, Stephany J, Smith, Trevor Rf, Mendoza, Janess, Broderick, Kate E, Montefiori, David C, Ferrari, Guido, Kulp, Daniel W, Humeau, Laurent M, Weiner, David B

Volltext

An elementary approach to electromagnetic momentum in matter von Medina, Rodrigo, Stephany, J

Volltext

A platform for functional assessment of large variant libraries in mammalian cells von Matreyek, Kenneth A, Stephany, Jason J, Fowler, Douglas M

Volltext

Elucidating the Molecular Determinants of Aβ Aggregation with Deep Mutational Scanning von Gray, Vanessa E, Sitko, Katherine, Kameni, Floriane Z Ngako, Williamson, Miriam, Stephany, Jason J, Hasle, Nicholas, Fowler, Douglas M

Volltext

An improved platform for functional assessment of large protein libraries in mammalian cells von Matreyek, Kenneth A, Stephany, Jason J, Chiasson, Melissa A, Hasle, Nicholas, Fowler, Douglas M

Volltext

Development of a novel screening tool for predicting Cochlear implant candidacy von Ngombu, Stephany J., Ray, Christin, Vasil, Kara, Moberly, Aaron C., Varadarajan, Varun V.

Volltext

Multiplex assessment of protein variant abundance by massively parallel sequencing von Matreyek, Kenneth A., Starita, Lea M., Stephany, Jason J., Martin, Beth, Chiasson, Melissa A., Gray, Vanessa E., Kircher, Martin, Khechaduri, Arineh, Dines, Jennifer N., Hause, Ronald J., Bhatia, Smita, Evans, William E., Relling, Mary V., Yang, Wenjian, Shendure, Jay, Fowler, Douglas M.

Volltext

Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1 von VEUGER, Stephany J, CURTIN, Nicola J, RICHARDSON, Caroline J, SMITH, Graeme C. M, DURKACZ, Barbara W

Volltext

Women's Experiences of Supervision and Professional Development von Valmas, Mary M, Himrich, Stephany J, Finn, Kate M

Volltext

Molecular determinants of Hsp90 dependence of Src kinase revealed by deep mutational scanning von Nguyen, Vanessa, Ahler, Ethan, Sitko, Katherine A., Stephany, Jason J., Maly, Dustin J., Fowler, Douglas M.

Volltext