Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease von Chu, Hiutung, Khosravi, Arya, Kusumawardhani, Indah P., Kwon, Alice H. K., Vasconcelos, Anilton C., Cunha, Larissa D., Mayer, Anne E., Shen, Yue, Wu, Wei-Li, Kambal, Amal, Targan, Stephan R., Xavier, Ramnik J., Ernst, Peter B., Green, Douglas R., McGovern, Dermot P. B., Virgin, Herbert W., Mazmanian, Sarkis K.

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Microbiota activation and regulation of innate and adaptive immunity von Alexander, Katie L., Targan, Stephan R., Elson III, Charles O.

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Immunopathogenesis of inflammatory bowel disease von Shih, David Q, Targan, Stephan R

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Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis von Shih, David Q, Barrett, Robert, Zhang, Xiaolan, Yeager, Nicole, Koon, Hon Wai, Phaosawasdi, Piangwarin, Song, Yahui, Ko, Brian, Wong, Michelle H, Michelsen, Kathrin S, Martins, Gislaine, Pothoulakis, Charalabos, Targan, Stephan R

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Future Therapeutic Approaches for Inflammatory Bowel Diseases von Plevy, Scott E, Targan, Stephan R

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Enhanced Utilization of Induced Pluripotent Stem Cell–Derived Human Intestinal Organoids Using Microengineered Chips von Workman, Michael J, Gleeson, John P, Troisi, Elissa J, Estrada, Hannah Q, Kerns, S. Jordan, Hinojosa, Christopher D, Hamilton, Geraldine A, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J

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Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis von Wenxiu, Jia, Mingyue, Yang, Fei, Han, Yuxin, Luo, Mengyao, Wu, Chenyang, Li, Jia, Song, Hong, Zhang, Shih, David Q., Targan, Stephan R., Xiaolan, Zhang

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Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids von Workman, Michael J, Troisi, Elissa, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis von Cho, Judy H, Taylor, Kent D, Daly, Mark J, Silverberg, Mark S, Nicolae, Dan L, Goyette, Philippe, Steinhart, A Hillary, Rotter, Jerome I, Schumm, L Philip, Duerr, Richard H, Shugart, Yin Yao, Griffiths, Anne M, Huett, Alan, Ippoliti, Andrew F, Bernard, Edmond-Jean, Kuballa, Petric, Xavier, Ramnik J, Barmada, M Michael, Rioux, John D, Datta, Lisa Wu, Green, Todd, Regueiro, Miguel, Targan, Stephan R, Brant, Steven R, Mei, Ling

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Natalizumab for the Treatment of Active Crohn’s Disease: Results of the ENCORE Trial von Targan, Stephan R, Feagan, Brian G, Fedorak, Richard N, Lashner, Bret A, Panaccione, Remo, Present, Daniel H, Spehlmann, Martina E, Rutgeerts, Paul J, Tulassay, Zsolt, Volfova, Miroslava, Wolf, Douglas C, Hernandez, Chito, Bornstein, Jeffrey, Sandborn, William J

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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD von Gleeson, John P, Estrada, Hannah Q, Yamashita, Michifumi, Svendsen, Clive N, Targan, Stephan R, Barrett, Robert J

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Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis von Zhang, Hong, Zheng, Libo, McGovern, Dermot P B, Hamill, Ariel M, Ichikawa, Ryan, Kanazawa, Yoshitake, Luu, Justin, Kumagai, Kotaro, Cilluffo, Marianne, Fukata, Masayuki, Targan, Stephan R, Underhill, David M, Zhang, Xiaolan, Shih, David Q

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Bacterial flagellin is a dominant antigen in Crohn disease von Lodes, Michael J, Cong, Yingzi, Elson, Charles O, Mohamath, Raodoh, Landers, Carol J, Targan, Stephan R, Fort, Madeline, Hershberg, Robert M

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Abatacept for Crohn's Disease and Ulcerative Colitis von Sandborn, William J, Colombel, Jean–Frederic, Sands, Bruce E, Rutgeerts, Paul, Targan, Stephan R, Panaccione, Remo, Bressler, Brian, Geboes, Karl, Schreiber, Stefan, Aranda, Richard, Gujrathi, Sheila, Luo, Allison, Peng, Yun, Salter–Cid, Luisa, Hanauer, Stephen B

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Defects in mucosal immunity leading to ulcerative colitis von Targan, Stephan R., Karp, Loren C.

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Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombina... von Biener-Ramanujan, Eva, Rosier, Florian, Coetzee, Simon G, McGovern, Dermot D P, Hazelett, Dennis, Targan, Stephan R, Gonsky, Rivkah

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Toll-like receptor 7 protects against intestinal inflammation and restricts the development of colonic tissue-resident memory CD8 + T cells von Hamade, Hussein, Tsuda, Masato, Oshima, Naoki, Stamps, Dalton T, Wong, Michelle H, Stamps, Jasmine T, Thomas, Lisa S, Salumbides, Brenda C, Jin, Caroline, Nunnelee, Jordan S, Dhall, Deepti, Targan, Stephan R, Michelsen, Kathrin S

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Biologic therapy of inflammatory bowel disease von Sandborn, William J., Targan, Stephan R.

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Increased Immune Reactivity Predicts Aggressive Complicating Crohn's Disease in Children von Dubinsky, Marla C, Kugathasan, Subra, Mei, Ling, Picornell, Yoana, Nebel, Justin, Wrobel, Iwona, Quiros, Antonio, Silber, Gary, Wahbeh, Ghassan, Katzir, Lirona, Vasiliauskas, Eric, Bahar, Ron, Otley, Anthony, Mack, David, Evans, Jonathan, Rosh, Joel, Hemker, Maria Oliva, Leleiko, Neal, Crandall, Wallace, Langton, Christine, Landers, Carol, Taylor, Kent D, Targan, Stephan R, Rotter, Jerome I, Markowitz, James, Hyams, Jeffrey

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Role of Cytokines in the Pathogenesis of Inflammatory Bowel Disease von Papadakis, Konstantinos A, Targan, Stephan R

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