Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers von Mathis, Carole, Poussin, Carine, Weisensee, Dirk, Gebel, Stephan, Hengstermann, Arnd, Sewer, Alain, Belcastro, Vincenzo, Xiang, Yang, Ansari, Sam, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C

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Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders von Hofmann-Apitius, Martin, Ball, Gordon, Gebel, Stephan, Bagewadi, Shweta, de Bono, Bernard, Schneider, Reinhard, Page, Matt, Kodamullil, Alpha Tom, Younesi, Erfan, Ebeling, Christian, Tegnér, Jesper, Canard, Luc

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MINERVA—a platform for visualization and curation of molecular interaction networks von Gawron, Piotr, Ostaszewski, Marek, Satagopam, Venkata, Gebel, Stephan, Mazein, Alexander, Kuzma, Michal, Zorzan, Simone, McGee, Fintan, Otjacques, Benoît, Balling, Rudi, Schneider, Reinhard

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Integration and Visualization of Translational Medicine Data for Better Understanding of Human Diseases von Satagopam, Venkata, Gu, Wei, Eifes, Serge, Gawron, Piotr, Ostaszewski, Marek, Gebel, Stephan, Barbosa-Silva, Adriano, Balling, Rudi, Schneider, Reinhard

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The Transcriptome of Nrf2−/− Mice Provides Evidence for Impaired Cell Cycle Progression in the Development of Cigarette Smoke–Induced Emphysematous Changes von Gebel, Stephan, Diehl, Svenja, Pype, Jan, Friedrichs, Bärbel, Weiler, Horst, Schüller, Jutta, Xu, Haiyan, Taguchi, Keiko, Yamamoto, Masayuki, Müller, Thomas

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Curating, Collecting, and Cataloguing Global COVID-19 Datasets for the Aim of Predicting Personalized Risk von Khatami, Sepehr Golriz, Sargsyan, Astghik, Russo, Maria Francesca, Domingo-Fernández, Daniel, Zaliani, Andrea, Kaladharan, Abish, Sethumadhavan, Priya, Mubeen, Sarah, Gadiya, Yojana, Karki, Reagon, Gebel, Stephan, Ruppa Surulinathan, Ram Kumar, Lage-Rupprecht, Vanessa, Archipovas, Saulius, Mingrone, Geltrude, Jacobs, Marc, Claussen, Carsten, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom

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The Kinetics of Transcriptomic Changes Induced by Cigarette Smoke in Rat Lungs Reveals a Specific Program of Defense, Inflammation, and Circadian Clock Gene Expression von Gebel, Stephan, Gerstmayer, Bernhard, Kuhl, Peter, Borlak, Jürgen, Meurrens, Kris, Müller, Thomas

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Construction of a Computable Network Model for DNA Damage, Autophagy, Cell Death, and Senescence von Gebel, Stephan, Lichtner, Rosemarie B., Frushour, Brian, Schlage, Walter K., Hoang, Vy, Talikka, Marja, Hengstermann, Arnd, Mathis, Carole, Veljkovic, Emilija, Peck, Michael, Peitsch, Manuel C., Deehan, Renee, Hoeng, Julia, Westra, Jurjen W.

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A Modular Cell-Type Focused Inflammatory Process Network Model for Non-Diseased Pulmonary Tissue von Westra, Jurjen W., Schlage, Walter K., Hengstermann, Arnd, Gebel, Stephan, Mathis, Carole, Thomson, Ty, Wong, Ben, Hoang, Vy, Veljkovic, Emilija, Peck, Michael, Lichtner, Rosemarie B., Weisensee, Dirk, Talikka, Marja, Deehan, Renee, Hoeng, Julia, Peitsch, Manuel C.

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A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture After Exposure to Cigarette Smoke In Vitro von Mathis, Carole, Gebel, Stephan, Poussin, Carine, Belcastro, Vincenzo, Sewer, Alain, Weisensee, Dirk, Hengstermann, Arnd, Ansari, Sam, Wagner, Sandra, Peitsch, Manuel C., Hoeng, Julia

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The COVID-19 Ontology von Sargsyan, Astghik, Kodamullil, Alpha Tom, Baksi, Shounak, Darms, Johannes, Madan, Sumit, Gebel, Stephan, Keminer, Oliver, Jose, Geena Mariya, Balabin, Helena, DeLong, Lauren Nicole, Kohler, Manfred, Jacobs, Marc, Hofmann-Apitius, Martin

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Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone von Jonat, Carsten, Rahmsdorf, Hans J., Park, Kun-Koo, Cato, Andrew C.B., Gebel, Stephan, Ponta, Helmut, Herrlich, Peter

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Integrative data semantics through a model-enabled data stewardship von Wegner, Philipp, Schaaf, Sebastian, Uebachs, Mischa, Domingo-Fernández, Daniel, Salimi, Yasamin, Gebel, Stephan, Sargsyan, Astghik, Birkenbihl, Colin, Springstubbe, Stephan, Klockgether, Thomas, Fluck, Juliane, Hofmann-Apitius, Martin, Kodamullil, Alpha Tom

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Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset von Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C.

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Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS^(TM)) von Xiang, Yang, Kogel, Ulrike, Gebel, Stephan, Peck, Michael J., Peitsch, Manuel C., Akmaev, Viatcheslav R., Hoeng, Julia

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Community-driven roadmap for integrated disease maps von Ostaszewski, Marek, Gebel, Stephan, Kuperstein, Inna, Mazein, Alexander, Zinovyev, Andrei, Dogrusoz, Ugur, Hasenauer, Jan, Fleming, Ronan M T, Le Novère, Nicolas, Gawron, Piotr, Ligon, Thomas, Niarakis, Anna, Nickerson, David, Weindl, Daniel, Balling, Rudi, Barillot, Emmanuel, Auffray, Charles, Schneider, Reinhard

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A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with co... von Kogel, Ulrike, Schlage, Walter K., Martin, Florian, Xiang, Yang, Ansari, Sam, Leroy, Patrice, Vanscheeuwijck, Patrick, Gebel, Stephan, Buettner, Ansgar, Wyss, Christoph, Esposito, Marco, Hoeng, Julia, Peitsch, Manuel C.

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Genes associated with Parkinson's disease respond to increasing polychlorinated biphenyl levels in the blood of healthy females von Bohler, Sacha, Krauskopf, Julian, Espín-Pérez, Almudena, Gebel, Stephan, Palli, Domenico, Rantakokko, Panu, Kiviranta, Hannu, Kyrtopoulos, Soterios A., Balling, Rudi, Kleinjans, Jos

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Design of the formalized and integrated Alzheimer’s Disease Ontology and its application in retrieving textual data via text mining von Zhang, Bide, Lage-Rupprecht, Vanessa, Wegner, Philipp, Sargsyan, Astghik, Gebel, Stephan, Jacobs, Marc, Klein, Jürgen, Hofmann-Apitius, Martin, Tom Kodamullil, Alpha

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Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms von Mazein, Alexander, Ostaszewski, Marek, Kuperstein, Inna, Watterson, Steven, Le Novère, Nicolas, Lefaudeux, Diane, De Meulder, Bertrand, Pellet, Johann, Balaur, Irina, Saqi, Mansoor, Nogueira, Maria Manuela, He, Feng, Parton, Andrew, Lemonnier, Nathanaël, Gawron, Piotr, Gebel, Stephan, Hainaut, Pierre, Ollert, Markus, Dogrusoz, Ugur, Barillot, Emmanuel, Zinovyev, Andrei, Schneider, Reinhard, Balling, Rudi, Auffray, Charles

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