Fast and inexpensive whole-genome sequencing library preparation from intact yeast cells von Vonesch, Sibylle C, Li, Shengdi, Szu Tu, Chelsea, Hennig, Bianca P, Dobrev, Nikolay, Steinmetz, and Lars M

Volltext

QTL analysis of high thermotolerance with superior and downgraded parental yeast strains reveals new minor QTLs and converges on novel causative alleles involved in RNA processing von Yang, Yudi, Foulquié-Moreno, Maria R, Clement, Lieven, Erdei, Eva, Tanghe, An, Schaerlaekens, Kristien, Dumortier, Françoise, Thevelein, Johan M

Volltext

Human haematopoietic stem cell lineage commitment is a continuous process von Velten, Lars, Haas, Simon F., Raffel, Simon, Blaszkiewicz, Sandra, Islam, Saiful, Hennig, Bianca P., Hirche, Christoph, Lutz, Christoph, Buss, Eike C., Nowak, Daniel, Boch, Tobias, Hofmann, Wolf-Karsten, Ho, Anthony D., Huber, Wolfgang, Trumpp, Andreas, Essers, Marieke A. G., Steinmetz, Lars M.

Volltext

Widespread Co-translational RNA Decay Reveals Ribosome Dynamics von Pelechano, Vicent, Wei, Wu, Steinmetz, Lars M.

Volltext

Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization von Baccin, Chiara, Al-Sabah, Jude, Velten, Lars, Helbling, Patrick M., Grünschläger, Florian, Hernández-Malmierca, Pablo, Nombela-Arrieta, César, Steinmetz, Lars M., Trumpp, Andreas, Haas, Simon

Volltext

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors von Haas, Simon, Hansson, Jenny, Klimmeck, Daniel, Loeffler, Dirk, Velten, Lars, Uckelmann, Hannah, Wurzer, Stephan, Prendergast, Áine M., Schnell, Alexandra, Hexel, Klaus, Santarella-Mellwig, Rachel, Blaszkiewicz, Sandra, Kuck, Andrea, Geiger, Hartmut, Milsom, Michael D., Steinmetz, Lars M., Schroeder, Timm, Trumpp, Andreas, Krijgsveld, Jeroen, Essers, Marieke A.G.

Volltext

Set3 HDAC Mediates Effects of Overlapping Noncoding Transcription on Gene Induction Kinetics von Kim, TaeSoo, Xu, Zhenyu, Clauder-Münster, Sandra, Steinmetz, Lars M., Buratowski, Stephen

Volltext

Gene regulation by antisense transcription von Pelechano, Vicent, Steinmetz, Lars M.

Volltext

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins von Castello, Alfredo, Fischer, Bernd, Eichelbaum, Katrin, Horos, Rastislav, Beckmann, Benedikt M., Strein, Claudia, Davey, Norman E., Humphreys, David T., Preiss, Thomas, Steinmetz, Lars M., Krijgsveld, Jeroen, Hentze, Matthias W.

Volltext

Extensive Degradation of RNA Precursors by the Exosome in Wild-Type Cells von Gudipati, Rajani Kanth, Xu, Zhenyu, Lebreton, Alice, Séraphin, Bertrand, Steinmetz, Lars M., Jacquier, Alain, Libri, Domenico

Volltext

Extensive transcriptional heterogeneity revealed by isoform profiling von Pelechano, Vicent, Wei, Wu, Steinmetz, Lars M.

Volltext

Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos von Zuo, Erwei, Sun, Yidi, Wei, Wu, Yuan, Tanglong, Ying, Wenqin, Sun, Hao, Yuan, Liyun, Steinmetz, Lars M., Li, Yixue, Yang, Hui

Volltext

RNA Polymerase II Collision Interrupts Convergent Transcription von Hobson, David J., Wei, Wu, Steinmetz, Lars M., Svejstrup, Jesper Q.

Volltext

High-speed fluorescence image-enabled cell sorting von Schraivogel, Daniel, Kuhn, Terra M, Rauscher, Benedikt, Rodríguez-Martínez, Marta, Paulsen, Malte, Owsley, Keegan, Middlebrook, Aaron, Tischer, Christian, Ramasz, Beáta, Ordoñez-Rueda, Diana, Dees, Martina, Cuylen-Haering, Sara, Diebold, Eric, Steinmetz, Lars M

Volltext

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics von Velten, Lars, Story, Benjamin A., Hernández-Malmierca, Pablo, Raffel, Simon, Leonce, Daniel R., Milbank, Jennifer, Paulsen, Malte, Demir, Aykut, Szu-Tu, Chelsea, Frömel, Robert, Lutz, Christoph, Nowak, Daniel, Jann, Johann-Christoph, Pabst, Caroline, Boch, Tobias, Hofmann, Wolf-Karsten, Müller-Tidow, Carsten, Trumpp, Andreas, Haas, Simon, Steinmetz, Lars M.

Volltext

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions von Grubert, Fabian, Zaugg, Judith B., Kasowski, Maya, Ursu, Oana, Spacek, Damek V., Martin, Alicia R., Greenside, Peyton, Srivas, Rohith, Phanstiel, Doug H., Pekowska, Aleksandra, Heidari, Nastaran, Euskirchen, Ghia, Huber, Wolfgang, Pritchard, Jonathan K., Bustamante, Carlos D., Steinmetz, Lars M., Kundaje, Anshul, Snyder, Michael

Volltext

Large-Scale Low-Cost NGS Library Preparation Using a Robust Tn5 Purification and Tagmentation Protocol von Hennig, Bianca P, Velten, Lars, Racke, Ines, Tu, Chelsea Szu, Thoms, Matthias, Rybin, Vladimir, Besir, Hüseyin, Remans, Kim, Steinmetz, Lars M

Volltext

Ultrasensitive proteome analysis using paramagnetic bead technology von Hughes, Christopher S, Foehr, Sophia, Garfield, David A, Furlong, Eileen E, Steinmetz, Lars M, Krijgsveld, Jeroen

Volltext

Cell sorters see things more clearly now von Schraivogel, Daniel, Steinmetz, Lars M

Volltext

Pooled Genome-Scale CRISPR Screens in Single Cells von Schraivogel, Daniel, Steinmetz, Lars M, Parts, Leopold

Volltext