Oncology clinical trial disruption during the COVID-19 pandemic: a COVID-19 and cancer outcomes study von Bakouny, Z, Labaki, C, Bhalla, S, Schmidt, A L, Steinharter, J A, Cocco, J, Tremblay, D A, Awad, M M, Kessler, A, Haddad, R I, Evans, M, Busser, F, Wotman, M, Curran, C R, Zimmerman, B S, Bouchard, G, Jun, T, Nuzzo, P V, Qin, Q, Hirsch, L, Feld, J, Kelleher, K M, Seidman, D, Huang, H, Anderson-Keightly, H M, El Zarif, T, Alaiwi, S Abou, Champagne, C, Rosenbloom, T D, Stewart, P S, Johnson, B E, Trinh, Q, Tolaney, S M, Galsky, M D, Choueiri, T K, Doroshow, D B

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Activity of cabozantinib (cabo) after PD-1/PD-L1 immune checkpoint blockade (ICB) in metastatic clear cell renal cell carcinoma (mccRCC) von McGregor, B.A., Lalani, A.-K., Xie, W., Steinharter, J.A., Martini, D.J., Nuzzo, P.V., Martinez Chanza, N., Harshman, L.C., Bilen, M.A., Choueiri, T.K.

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879PActivity of cabozantinib (cabo) after PD-1/PD-L1 immune checkpoint blockade (ICB) in metastatic clear cell renal cell carcinoma (mccRCC) von McGregor, B A, Lalani, A-K, Xie, W, Steinharter, J A, Martini, D J, Nuzzo, P V, Martinez Chanza, N, Harshman, L C, Bilen, M A, Choueiri, T K

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976PEfficacy of immune checkpoint inhibitors (ICI) and genomic alterations by body mass index (BMI) in advanced renal cell carcinoma (RCC) von Lalani, A-K A, Bakouny, Z, Farah, S, Xie, W, Flippot, R, Steinharter, J A, Nuzzo, P V, Fleischer, J, Pal, S K, Rathi, N, Hansen, A R, Donskov, F, Dudani, S, Yuasa, T, Vaishampayan, U, Subasri, M, Wells, J C, Basappa, N S, Heng, D Y C, Choueiri, T K

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Executive function is associated with balance and falls in older cancer survivors treated with chemotherapy: A cross-sectional study von McNeish, Brendan L., Dittus, Kim, Mossburg, Jurdan, Krant, Nicholas, Steinharter, John A., Feb, Kendall, Cote, Hunter, Hehir, Michael K., Reynolds, Rebecca, Redfern, Mark S., Rosano, Caterina, Richardson, James K., Kolb, Noah

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Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma von Lalani, Aly-Khan A, Xie, Wanling, Martini, Dylan J, Steinharter, John A, Norton, Craig K, Krajewski, Katherine M, Duquette, Audrey, Bossé, Dominick, Bellmunt, Joaquim, Van Allen, Eliezer M, McGregor, Bradley A, Creighton, Chad J, Harshman, Lauren C, Choueiri, Toni K

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Activity of cabozantinib after immune checkpoint blockade in metastatic clear-cell renal cell carcinoma von McGregor, Bradley A., Lalani, Aly-Khan A., Xie, Wanling, Steinharter, John A., E. Bakouny, Ziad, Martini, Dylan J., Fleischer, Justin H., Abou-Alaiwi, Sarah, Nassar, Amin, Nuzzo, Pier V., Kaymakcalan, Marina D., Braun, David A., Wei, Xiao X., Harshman, Lauren C., Bilen, Mehmet A., Choueiri, Toni K.

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Upfront Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors or Targeted Therapy: An Observational Study from the International M... von Bakouny, Ziad, El Zarif, Talal, Dudani, Shaan, Connor Wells, J., Gan, Chun Loo, Donskov, Frede, Shapiro, Julia, Davis, Ian D., Parnis, Francis, Ravi, Praful, Steinharter, John A., Agarwal, Neeraj, Alva, Ajjai, Wood, Lori, Kapoor, Anil, Ruiz Morales, Jose M., Kollmannsberger, Christian, Beuselinck, Benoit, Xie, Wanling, Heng, Daniel Y.C., Choueiri, Toni K.

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Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features von McGregor, Bradley A., McKay, Rana R., Braun, David A., Werner, Lillian, Gray, Kathryn P., Flaifel, Abdallah, Signoretti, Sabina, Hirsch, Michelle S., Steinharter, John A., Bakouny, Ziad, Flippot, Ronan, Wei, Xiao X., Choudhury, Atish, Kilbridge, Kerry, Freeman, Gordon J., Van Allen, Eliezer, Harshman, Lauren C., McDermott, David F., Vaishampayan, Ulka, Choueiri, Toni K.

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Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors von Abou Alaiwi, Sarah, Nassar, Amin H., Xie, Wanling, Bakouny, Ziad, Berchuck, Jacob E., Braun, David A., Baca, Sylvan C., Nuzzo, Pier Vitale, Flippot, Ronan, Mouhieddine, Tarek H., Spurr, Liam F., Li, Yvonne Y., Li, Taiwen, Flaifel, Abdallah, Steinharter, John A., Margolis, Claire A., Vokes, Natalie I., Du, Heng, Shukla, Sachet A., Cherniack, Andrew D., Sonpavde, Guru, Haddad, Robert I., Awad, Mark M., Giannakis, Marios, Hodi, F. Stephen, Liu, X. Shirley, Signoretti, Sabina, Kadoch, Cigall, Freedman, Matthew L., Kwiatkowski, David J., Van Allen, Eliezer M., Choueiri, Toni K.

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Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma von Bakouny, Ziad, Braun, David A., Shukla, Sachet A., Pan, Wenting, Gao, Xin, Hou, Yue, Flaifel, Abdallah, Tang, Stephen, Bosma-Moody, Alice, He, Meng Xiao, Vokes, Natalie, Nyman, Jackson, Xie, Wanling, Nassar, Amin H., Abou Alaiwi, Sarah, Flippot, Ronan, Bouchard, Gabrielle, Steinharter, John A., Nuzzo, Pier Vitale, Ficial, Miriam, Sant’Angelo, Miriam, Forman, Juliet, Berchuck, Jacob E., Dudani, Shaan, Bi, Kevin, Park, Jihye, Camp, Sabrina, Sticco-Ivins, Maura, Hirsch, Laure, Baca, Sylvan C., Wind-Rotolo, Megan, Ross-Macdonald, Petra, Sun, Maxine, Lee, Gwo-Shu Mary, Chang, Steven L., Wei, Xiao X., McGregor, Bradley A., Harshman, Lauren C., Genovese, Giannicola, Ellis, Leigh, Pomerantz, Mark, Hirsch, Michelle S., Freedman, Matthew L., Atkins, Michael B., Wu, Catherine J., Ho, Thai H., Linehan, W. Marston, McDermott, David F., Heng, Daniel Y. C., Viswanathan, Srinivas R., Signoretti, Sabina, Van Allen, Eliezer M., Choueiri, Toni K.

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Cancer Care Disparities during the COVID-19 Pandemic: COVID-19 and Cancer Outcomes Study von Schmidt, Andrew L., Bakouny, Ziad, Bhalla, Sheena, Steinharter, John A., Tremblay, Douglas A., Awad, Mark M., Kessler, Alaina J., Haddad, Robert I., Evans, Michelle, Busser, Fiona, Wotman, Michael, Curran, Catherine R., Zimmerman, Brittney S., Bouchard, Gabrielle, Jun, Tomi, Nuzzo, Pier V., Qin, Qian, Hirsch, Laure, Feld, Jonathan, Kelleher, Kaitlin M., Seidman, Danielle, Huang, Hsin-Hui, Anderson-Keightly, Heather M., Abou Alaiwi, Sarah, Rosenbloom, Talia D., Stewart, Penina S., Galsky, Matthew D., Choueiri, Toni K., Doroshow, Deborah B.

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Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma von Braun, David A., Hou, Yue, Bakouny, Ziad, Ficial, Miriam, Sant’ Angelo, Miriam, Forman, Juliet, Ross-Macdonald, Petra, Berger, Ashton C., Jegede, Opeyemi A., Elagina, Liudmilla, Steinharter, John, Sun, Maxine, Wind-Rotolo, Megan, Pignon, Jean-Christophe, Cherniack, Andrew D., Lichtenstein, Lee, Neuberg, Donna, Catalano, Paul, Freeman, Gordon J., Sharpe, Arlene H., McDermott, David F., Van Allen, Eliezer M., Signoretti, Sabina, Wu, Catherine J., Shukla, Sachet A., Choueiri, Toni K.

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Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma von Bade, Rory M., Schehr, Jennifer L., Emamekhoo, Hamid, Gibbs, Benjamin K., Rodems, Tamara S., Mannino, Matthew C., Desotelle, Joshua A., Heninger, Erika, Stahlfeld, Charlotte N., Sperger, Jamie M., Singh, Anupama, Wolfe, Serena K., Niles, David J., Arafat, Waddah, Steinharter, John A., Jason Abel, E., Beebe, David J., Wei, Xiao X., McKay, Rana R., Choueri, Toni K., Lang, Joshua M.

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Durable Clinical Benefit in Metastatic Renal Cell Carcinoma Patients Who Discontinue PD-1/PD-L1 Therapy for Immune-Related Adverse Events von Martini, Dylan J, Hamieh, Lana, McKay, Rana R, Harshman, Lauren C, Brandao, Raphael, Norton, Craig K, Steinharter, John A, Krajewski, Katherine M, Gao, Xin, Schutz, Fabio A, McGregor, Bradley, Bossé, Dominick, Lalani, Aly-Khan A, De Velasco, Guillermo, Michaelson, M Dror, McDermott, David F, Choueiri, Toni K

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Progressive immune dysfunction with advancing disease stage in renal cell carcinoma von Braun, David A., Street, Kelly, Burke, Kelly P., Cookmeyer, David L., Denize, Thomas, Pedersen, Christina B., Gohil, Satyen H., Schindler, Nicholas, Pomerance, Lucas, Hirsch, Laure, Bakouny, Ziad, Hou, Yue, Forman, Juliet, Huang, Teddy, Li, Shuqiang, Cui, Ang, Keskin, Derin B., Steinharter, John, Bouchard, Gabrielle, Sun, Maxine, Pimenta, Erica M., Xu, Wenxin, Mahoney, Kathleen M., McGregor, Bradley A., Hirsch, Michelle S., Chang, Steven L., Livak, Kenneth J., McDermott, David F., Shukla, Sachet A., Olsen, Lars R., Signoretti, Sabina, Sharpe, Arlene H., Irizarry, Rafael A., Choueiri, Toni K., Wu, Catherine J.

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Integrative clinical and molecular characterization of translocation renal cell carcinoma von Bakouny, Ziad, Sadagopan, Ananthan, Ravi, Praful, Metaferia, Nebiyou Y, Li, Jiao, AbuHammad, Shatha, Tang, Stephen, Denize, Thomas, Garner, Emma R, Gao, Xin, Braun, David A, Hirsch, Laure, Steinharter, John A, Bouchard, Gabrielle, Walton, Emily, West, Destiny, Labaki, Chris, Dudani, Shaan, Gan, Chun-Loo, Sethunath, Vidyalakshmi, Carvalho, Filipe L F, Imamovic, Alma, Ricker, Cora, Vokes, Natalie I, Nyman, Jackson, Berchuck, Jacob E, Park, Jihye, Hirsch, Michelle S, Haq, Rizwan, Mary Lee, Gwo-Shu, McGregor, Bradley A, Chang, Steven L, Feldman, Adam S, Wu, Catherine J, McDermott, David F, Heng, Daniel Y C, Signoretti, Sabina, Van Allen, Eliezer M, Choueiri, Toni K, Viswanathan, Srinivas R

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Response to single agent PD-1 inhibitor after progression on previous PD-1/PD-L1 inhibitors: a case series von Martini, Dylan J, Lalani, Aly-Khan A, Bossé, Dominick, Steinharter, John A, Harshman, Lauren C, Hodi, F Stephen, Ott, Patrick A, Choueiri, Toni K

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Real‐World Assessment of Clinical Outcomes Among First‐Line Sunitinib Patients with Clear Cell Metastatic Renal Cell Carcinoma (mRCC) by the International mRCC Database Consortium... von Savard, Marie‐France, Wells, J. Connor, Graham, Jeffrey, Dudani, Shaan, Steinharter, John A., McGregor, Bradley A., Donskov, Frede, Bjarnason, Georg A., Vaishampayan, Ulka N., Hansen, Aaron R., Iafolla, Marco A.J., Zanotti, Giovanni, Huynh, Lynn, Chang, Rose, Duh, Mei S., Heng, Daniel Y.C.

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Effect of Antibiotic Use on Outcomes with Systemic Therapies in Metastatic Renal Cell Carcinoma von Lalani, Aly-Khan A., Xie, Wanling, Braun, David A., Kaymakcalan, Marina, Bossé, Dominick, Steinharter, John A., Martini, Dylan J., Simantov, Ronit, Lin, Xun, Wei, Xiao X., McGregor, Bradley A., McKay, Rana R., Harshman, Lauren C., Choueiri, Toni K.

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