Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor von Nelson, Christopher A., Wilen, Craig B., Dai, Ya-Nan, Orchard, Robert C., Kim, Arthur S., Stegeman, Roderick A., Hsieh, Leon L., Smith, Thomas J., Virgin, Herbert W., Fremont, Daved H.

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Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death von Houl, Jerry H., Ye, Zu, Brosey, Chris A., Balapiti-Modarage, Lakshitha P. F., Namjoshi, Sarita, Bacolla, Albino, Laverty, Daniel, Walker, Brian L., Pourfarjam, Yasin, Warden, Leslie S., Babu Chinnam, Naga, Moiani, Davide, Stegeman, Roderick A., Chen, Mei-Kuang, Hung, Mien-Chie, Nagel, Zachary D., Ellenberger, Tom, Kim, In-Kwon, Jones, Darin E., Ahmed, Zamal, Tainer, John A.

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A Quantitative Assay Reveals Ligand Specificity of the DNA Scaffold Repair Protein XRCC1 and Efficient Disassembly of Complexes of XRCC1 and the Poly(ADP-ribose) Polymerase 1 by Po... von Kim, In-Kwon, Stegeman, Roderick A., Brosey, Chris A., Ellenberger, Tom

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Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element von Kim, In-Kwon, Kiefer, James R, Ho, Chris M W, Stegeman, Roderick A, Classen, Scott, Tainer, John A, Ellenberger, Tom

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents von Kurumbail, Ravi G, Stevens, Anna M, Gierse, James K, McDonald, Joseph J, Stegeman, Roderick A, Pak, Jina Y, Gildehaus, Daniel, iyashiro, Julie M, Penning, Thomas D, Seibert, Karen, Isakson, Peter C, Stallings, William C

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Structural Bioinformatics-Based Prediction of Exceptional Selectivity of p38 MAP Kinase Inhibitor PH-797804 von Xing, Li, Shieh, Huey S, Selness, Shaun R, Devraj, Rajesh V, Walker, John K, Devadas, Balekudru, Hope, Heidi R, Compton, Robert P, Schindler, John F, Hirsch, Jeffrey L, Benson, Alan G, Kurumbail, Ravi G, Stegeman, Roderick A, Williams, Jennifer M, Broadus, Richard M, Walden, Zara, Monahan, Joseph B

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Design, Synthesis, and Crystal Structure of Selective 2-Pyridone Tissue Factor VIIa Inhibitors von Parlow, John J, Kurumbail, Ravi G, Stegeman, Roderick A, Stevens, Anna M, Stallings, William C, South, Michael S

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Design, Parallel Synthesis, and Crystal Structures of Pyrazinone Antithrombotics as Selective Inhibitors of the Tissue Factor VIIa Complex von Parlow, John J, Case, Brenda L, Dice, Thomas A, Fenton, Ricky L, Hayes, Michael J, Jones, Darin E, Neumann, William L, Wood, Rhonda S, Lachance, Rhonda M, Girard, Thomas J, Nicholson, Nancy S, Clare, Michael, Stegeman, Roderick A, Stevens, Anna M, Stallings, William C, Kurumbail, Ravi G, South, Michael S

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Three-dimensional structure of human cytomegalovirus protease von Shieh, Huey-Sheng, Kurumbail, Ravi G, Stevens, Anna M, Stegeman, Roderick A, Sturman, Eric J, Pak, Jina Y, Wittwer, Arthur J, Palmier, Mark O, Wiegand, Roger C, Holwerda, Barry C, Stallings, William C

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2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor von Trujillo, John I, Kiefer, James R, Huang, Wei, Thorarensen, Atli, Xing, Li, Caspers, Nicole L, Day, Jacqueline E, Mathis, Karl J, Kretzmer, Kuniko K, Reitz, Beverley A, Weinberg, Robin A, Stegeman, Roderick A, Wrightstone, Ann, Christine, Lori, Compton, Robert, Li, Xiong

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Structural insights into the stereochemistry of the cyclooxygenase reaction von Kurumbail, Ravi G, Kiefer, James R, Pawlitz, Jennifer L, Moreland, Kirby T, Stegeman, Roderick A, Hood, William F, Gierse, James K, Stevens, Anna M, Goodwin, Douglas C, Rowlinson, Scott W, Marnett, Lawrence J, Stallings, William C

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Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa von SCHWEITZER, Barbara A, NEUMANN, William L, SOUTH, Michael S, RAHMAN, Hayat K, KUSTURIN, Carrie L, SAMPLE, Kirby R, PODA, Gennadiy I, KURUMBAIL, Ravi G, STEVENS, Anna M, STEGEMAN, Roderick A, STALLINGS, William C

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Synthesis and Crystal Structures of Substituted Benzenes and Benzoquinones as Tissue Factor VIIa Inhibitors von Parlow, John J, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, South, Michael S

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Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex von South, Michael S., Case, Brenda L., Wood, Rhonda S., Jones, Darin E., Hayes, Michael J., Girard, Thomas J., Lachance, Rhonda M., Nicholson, Nancy S., Clare, Michael, Stevens, Anna M., Stegeman, Roderick A., Stallings, William C., Kurumbail, Ravi G., Parlow, John J.

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Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue Factor VIIa complex von PARLOW, John J, KURUMBAIL, Ravi G, STEGEMAN, Roderick A, STEVENS, Anna M, STALLINGS, William C, SOUTH, Michael S

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Polymer-Assisted Solution-Phase Library Synthesis and Crystal Structure of α-Ketothiazoles as Tissue Factor VIIa Inhibitors von Parlow, John J, Dice, Thomas A, Lachance, Rhonda M, Girard, Thomas J, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, South, Michael S

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Polymer-Assisted solution-Phase (PASP) parallel synthesis of an α-Ketothiazole library as tissue factor VIIa inhibitors von South, Michael S, Dice, Thomas A, Girard, Thomas J, Lachance, Rhonda M, Stevens, Anna M, Stegeman, Roderick A, Stallings, William C, Kurumbail, Ravi G, Parlow, John J

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Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a unique substrate-binding element von Kim, In-Kwon, Kiefer, James R., Ho, Chris M. W., Stegeman, Roderick A., Classen, Scott, Tainer, John A., Ellenberger, Tom

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Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere von Vazquez, Michael L, Bryant, Martin L, Clare, Michael, DeCrescenzo, Gary A, Doherty, Elizabeth M, Freskos, John N, Getman, Daniel P, Houseman, Kathryn A, Julien, Janet A, Kocan, Geralyn P, Mueller, Richard A, Shieh, Huey-Sheng, Stallings, William C, Stegeman, Roderick A, Tilley, John J

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Three-dimensional structure of human cytomegalovirus protease von Shieh, Huey-Sheng, Kurumbail, Ravi G, Stevens, Anna M, Stegeman, Roderick A, Sturman, Eric J, Pak, Jina Y, Wittwer, Arthur J, Palmier, Mark O, Wiegand, Roger C, Holwerda, Barry C, Stallings, William C

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