Liver X receptor biology and pharmacology: new pathways, challenges and opportunities von Jakobsson, Tomas, Treuter, Eckardt, Gustafsson, Jan-Åke, Steffensen, Knut R

Volltext

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils von Raccosta, Laura, Fontana, Raffaella, Maggioni, Daniela, Lanterna, Claudia, Villablanca, Eduardo J, Paniccia, Aida, Musumeci, Andrea, Chiricozzi, Elena, Trincavelli, Maria Letizia, Daniele, Simona, Martini, Claudia, Gustafsson, Jan-Ake, Doglioni, Claudio, Feo, Safiyè Gonzalvo, Leiva, Andrea, Ciampa, Maria Grazia, Mauri, Laura, Sensi, Cristina, Prinetti, Alessandro, Eberini, Ivano, Mora, J Rodrigo, Bordignon, Claudio, Steffensen, Knut R, Sonnino, Sandro, Sozzani, Silvano, Traversari, Catia, Russo, Vincenzo

Volltext

LXR‐dependent and ‐independent effects of oxysterols on immunity and tumor growth von Traversari, Catia, Sozzani, Silvano, Steffensen, Knut R., Russo, Vincenzo

Volltext

Genome-Wide Profiling of Liver X Receptor, Retinoid X Receptor, and Peroxisome Proliferator-Activated Receptor α in Mouse Liver Reveals Extensive Sharing of Binding Sites von Boergesen, Michael, Pedersen, Thomas Åskov, Gross, Barbara, van Heeringen, Simon J., Hagenbeek, Dik, Bindesbøll, Christian, Caron, Sandrine, Lalloyer, Fanny, Steffensen, Knut R., Nebb, Hilde I., Gustafsson, Jan-Åke, Stunnenberg, Hendrik G., Staels, Bart, Mandrup, Susanne

Volltext

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells von Candelaria, Nicholes R, Addanki, Sridevi, Zheng, Jine, Nguyen-Vu, Trang, Karaboga, Husna, Dey, Prasenjit, Gabbi, Chiara, Vedin, Lise-Lotte, Liu, Ka, Wu, Wanfu, Jonsson, Philip K, Lin, Jean Z, Su, Fei, Bollu, Lakshmi Reddy, Hodges, Sally E, McElhany, Amy L, Issazadeh, Mehdi A, Fisher, William E, Ittmann, Michael M, Steffensen, Knut R, Gustafsson, Jan-Åke, Lin, Chin-Yo

Volltext

Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans von Minniti, Mirko E., Pedrelli, Matteo, Vedin, Lise‐Lotte, Delbès, Anne‐Sophie, Denis, Raphaël G.P., Öörni, Katariina, Sala, Claudia, Pirazzini, Chiara, Thiagarajan, Divya, Nurmi, Harri J., Grompe, Markus, Mills, Kevin, Garagnani, Paolo, Ellis, Ewa C.S., Strom, Stephen C., Luquet, Serge H., Wilson, Elizabeth M., Bial, John, Steffensen, Knut R., Parini, Paolo

Volltext

Are Synthetic Compounds that Silence the Liver-X-Receptor the Next Generation of Anti-cancer Drugs? von Steffensen, Knut R.

Volltext

Emerging role of thyroid hormone metabolites von Gnocchi, D., Steffensen, K. R., Bruscalupi, G., Parini, P.

Volltext

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells von Vedin, Lise-Lotte, Lewandowski, Sebastian A., Parini, Paolo, Gustafsson, Jan-Åke, Steffensen, Knut R.

Volltext

Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status von Ghaddab-Zroud, Rym, Seugnet, Isabelle, Steffensen, Knut R, Demeneix, Barbara A, Clerget-Froidevaux, Marie-Stéphanie

Volltext

Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice von Pedrelli, Matteo, Davoodpour, Padideh, Degirolamo, Chiara, Gomaraschi, Monica, Graham, Mark, Ossoli, Alice, Larsson, Lilian, Calabresi, Laura, Gustafsson, Jan-Åke, Steffensen, Knut R, Eriksson, Mats, Parini, Paolo

Volltext

Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism von Nguyen-Vu, Trang, Vedin, Lise-Lotte, Liu, Ka, Jonsson, Philip, Lin, Jean Z, Candelaria, Nicholes R, Candelaria, Lindsay P, Addanki, Sridevi, Williams, Cecilia, Gustafsson, Jan-Åke, Steffensen, Knut R, Lin, Chin-Yo

Volltext

Routine noninvasive prenatal screening for fetal RHD in plasma of RhD-negative pregnant women-2 years of screening experience from Denmark von Banch Clausen, F., Steffensen, R., Christiansen, M., Rudby, M., Jakobsen, M. A., Jakobsen, T. R., Krog, G. R., Madsen, R. D., Nielsen, K. R., Rieneck, K., Sprogøe, U., Homburg, K. M., Baech, J., Dziegiel, M. H., Grunnet, N.

Volltext

Srebf1 Controls Midbrain Dopaminergic Neurogenesis von Toledo, Enrique M., Yang, Shanzheng, Gyllborg, Daniel, van Wijk, Kim E., Sinha, Indranil, Varas-Godoy, Manuel, Grigsby, Christopher L., Lönnerberg, Peter, Islam, Saiful, Steffensen, Knut R., Linnarsson, Sten, Arenas, Ernest

Volltext

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice von Korf, Hannelie, Vander Beken, Seppe, Romano, Marta, Steffensen, Knut R, Stijlemans, Benoît, Gustafsson, Jan-Ake, Grooten, Johan, Huygen, Kris

Volltext

Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice von González-Granillo, M., Steffensen, K. R., Granados, O., Torres, N., Korach-André, M., Ortíz, V., Aguilar-Salinas, C., Jakobsson, T., Díaz-Villaseñor, A., Loza-Valdes, A., Hernandez-Pando, R., Gustafsson, J.-Å., Tovar, A. R.

Volltext

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S] von Bindesbøll, Christian, Fan, Qiong, Nørgaard, Rikke C., MacPherson, Laura, Ruan, Hai-Bin, Wu, Jing, Pedersen, Thomas Å., Steffensen, Knut R., Yang, Xiaoyong, Matthews, Jason, Mandrup, Susanne, Nebb, Hilde I., Grønning-Wang, Line M.

Volltext

Putative Metabolic Effects of the Liver X Receptor (LXR) von STEFFENSEN, Knut R, GUSTAFSSON, Jan-Ake

Volltext

High MBL-expressing genotypes are associated with deterioration in renal function in type 2 diabetes von Dørflinger, G H, Høyem, P H, Laugesen, E, Østergaard, J A, Funck, K L, Steffensen, R, Poulsen, P L, Hansen, T K, Bjerre, M

Volltext

Soat2 ties cholesterol metabolism to β‐oxidation and glucose tolerance in male mice von Pramfalk, Camilla, Ahmed, Osman, Pedrelli, Matteo, Minniti, Mirko E., Luquet, Serge, Denis, Raphaël GP, Olin, Maria, Härdfeldt, Jennifer, Vedin, Lise‐Lotte, Steffensen, Knut R, Rydén, Mikael, Hodson, Leanne, Eriksson, Mats, Parini, Paolo

Volltext