Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N‑[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration o... von Werner, Stefan, Mesch, Stefanie, Hillig, Roman C, ter Laak, Antonius, Klint, Julie, Neagoe, Ioana, Laux-Biehlmann, Alexis, Dahllöf, Henrik, Bräuer, Nico, Puetter, Vera, Nubbemeyer, Reinhard, Schulz, Simone, Bairlein, Michaela, Zollner, Thomas M, Steinmeyer, Andreas

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From a Library of MAG Antagonists to Nanomolar CD22 Ligands von Mesch, Stefanie, Lemme, Katrin, Wittwer, Matthias, Koliwer-Brandl, Hendrik, Schwardt, Oliver, Kelm, Sørge, Ernst, Beat

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Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation von Mesch, Stefanie, Moser, Delia, Strasser, Daniel S, Kelm, Antje, Cutting, Brian, Rossato, Gianluca, Vedani, Angelo, Koliwer-Brandl, Hendrik, Wittwer, Matthias, Rabbani, Said, Schwardt, Oliver, Kelm, Soerge, Ernst, Beat

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Amino Acid-Based Reoxidants for Aminohydroxylation: Application to the Construction of Amino Acid-Amino Alcohol Conjugates von Donohoe, Timothy J., Callens, Cedric K. A., Flores, Aida, Mesch, Stefanie, Poole, Darren L., Roslan, Ishmael A.

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Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein von Schwardt, Oliver, Koliwer-Brandl, Hendrik, Zimmerli, Raphael, Mesch, Stefanie, Rossato, Gianluca, Spreafico, Morena, Vedani, Angelo, Kelm, Sørge, Ernst, Beat

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Synthesis of sialic acid derivatives as ligands for the myelin-associated glycoprotein (MAG) von Shelke, Sachin V., Gao, Gan-Pan, Mesch, Stefanie, Gäthje, Heiko, Kelm, Soerge, Schwardt, Oliver, Ernst, Beat

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Discovery of BAY-390, a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist von Mesch, Stefanie, Walter, Daryl, Laux-Biehlmann, Alexis, Basting, Daniel, Flanagan, Stuart, Miyatake Ondozabal, Hideki, Bäurle, Stefan, Pearson, Christopher, Jenkins, James, Elves, Philip, Hess, Stephen, Coelho, Anne-Marie, Rotgeri, Andrea, Bothe, Ulrich, Nawaz, Schanila, Zollner, Thomas M., Steinmeyer, Andreas

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Novel Macrocyclic NLRP3 Inhibitors von Mesch, Stefanie, Shannon, Jonathan, Miller, David, MacLeod, Angus, Bouché, Léa, Johnston, Heather J., Matthews, Kim, Paehler, Axel, Best, Stuart, Guba, Wolfgang, Alanine, Thomas, Halai, Reena, Charge, Lorna, Garside, Samantha, Thom, Stephen, Incerti-Pradillos, Celia, McPherson, Christopher, Carrillo, Jokin, St-Gallay, Steve, Rigo, Pierre, Schlicht, Sonja, Hendrick, Alan G., Lerner, Christian, Piali, Luca, Blaising, Julie, Mracsko, Eva Z., Jaeschke, Georg, Cooper, Matthew A.

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From the Ganglioside GQ1b? to Glycomimetic Antagonists of the Myelin-Associated Glycoprotein (MAG) von Ernst, Beat, Schwardt, Oliver, Mesch, Stefanie, Wittwer, Matthias, Rossato, Gianluca, Vedani, Angelo

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Discovery of Orally Available and Brain Penetrant AEP Inhibitors von Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn

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Kinetic and thermodynamic properties of MAG antagonists von Mesch, Stefanie, Lemme, Katrin, Koliwer-Brandl, Hendrik, Strasser, Daniel S., Schwardt, Oliver, Kelm, Soerge, Ernst, Beat

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Examination of the Biological Role of the α(2→6)-Linked Sialic Acid in Gangliosides Binding to the Myelin-Associated Glycoprotein (MAG) von Schwardt, Oliver, Gäthje, Heiko, Vedani, Angelo, Mesch, Stefanie, Gao, Gan-Pan, Spreafico, Morena, von Orelli, Johannes, Kelm, Sørge, Ernst, Beat

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From the ganglioside GQ1balpha to glycomimetic antagonists of the myelin-associated glycoprotein (MAG) von Ernst, Beat, Schwardt, Oliver, Mesch, Stefanie, Wittwer, Matthias, Rossato, Gianluca, Vedani, Angelo

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NOVEL COMPOUNDS von JAESCHKE, Georg, TOSSTORFF, Andreas Michael, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina

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TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS von JAESCHKE, Georg, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina, SHANNON, Jonathan Martin

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NLRP3 INHIBITORS von JAESCHKE, Georg, TOSSTORFF, Andreas Michael, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina

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INHIBIDORES DE NLRP3 von JAESCHKE, Georg, TOSSTORFF, Andreas Michael, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina

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NLRP3 INHIBITORS von JAESCHKE, Georg, STEINER, Sandra, AITKEN, Lewis Scott, SCHNIDER, Christian, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina, SHANNON, Jonathan Martin

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HETEROCYCLIC NLRP3 INHIBITORS von JAESCHKE, Georg, TOSSTORFF, Andreas Michael, STEINER, Sandra, AITKEN, Lewis Scott, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina

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NLRP3 INHIBITORS von JAESCHKE, Georg, TOSSTORFF, Andreas Michael, BOUCHE, Lea Aurelie, GUBA, Wolfgang, MESCH, Stefanie Katharina

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