Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner von Luis, Tiago C., Barkas, Nikolaos, Carrelha, Joana, Giustacchini, Alice, Mazzi, Stefania, Norfo, Ruggiero, Wu, Bishan, Aliouat, Affaf, Guerrero, Jose A., Rodriguez-Meira, Alba, Bouriez-Jones, Tiphaine, Macaulay, Iain C., Jasztal, Maria, Zhu, Guangheng, Ni, Heyu, Robson, Matthew J., Blakely, Randy D., Mead, Adam J., Nerlov, Claus, Ghevaert, Cedric, Jacobsen, Sten Eirik W.

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Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes von Roy, Anita, Lordier, Larissa, Mazzi, Stefania, Chang, Yunhua, Lapierre, Valérie, Larghero, Jérome, Debili, Najet, Raslova, Hana, Vainchenker, William

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Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis von Plo, Isabelle, Bellanné-Chantelot, Christine, Mosca, Matthieu, Mazzi, Stefania, Marty, Caroline, Vainchenker, William

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Non-hierarchically related HSCs replenish platelets by distinct progenitor pathways von Mazzi, S, Jacobsen, SEW

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Megakaryocyte and polyploidization von Mazzi, Stefania, Lordier, Larissa, Debili, Najet, Raslova, Hana, Vainchenker, William

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model von Arkoun, Brahim, Robert, Elie, Boudia, Fabien, Mazzi, Stefania, Dufour, Virginie, Siret, Aurélie, Mammasse, Yasmine, Aid, Zakia, Vieira, Matthieu, Imanci, Aygun, Aglave, Marine, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Hermine, Olivier, Droin, Nathalie, Debili, Najet, Plo, Isabelle, Malinge, Sébastien, Soler, Eric, Raslova, Hana, Mercher, Thomas, Vainchenker, William

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Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation von Dimitriou, M, Mortera-Blanco, T, Tobiasson, M, Mazzi, S, Lehander, M, Hoegstrand, K, Karimi, M, Walldin, G, Jansson, M, Vonlanthen, S, Ljungman, P, Langemeijer, S, Yoshizato, T, Hellstroem-Lindberg, E, Woll, PS, Jacobsen, SEW

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Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells von Carrelha, Joana, Mazzi, Stefania, Winroth, Axel, Hagemann-Jensen, Michael, Ziegenhain, Christoph, Högstrand, Kari, Seki, Masafumi, Brennan, Margs S, Lehander, Madeleine, Wu, Bishan, Meng, Yiran, Markljung, Ellen, Norfo, Ruggiero, Ishida, Hisashi, Belander Strålin, Karin, Grasso, Francesca, Simoglou Karali, Christina, Aliouat, Affaf, Hillen, Amy, Chari, Edwin, Siletti, Kimberly, Thongjuea, Supat, Mead, Adam J, Linnarsson, Sten, Nerlov, Claus, Sandberg, Rickard, Yoshizato, Tetsuichi, Woll, Petter S, Jacobsen, Sten Eirik W

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Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells von Carrelha, Joana, Mazzi, Stefania, Winroth, Axel, Hagemann-Jensen, Michael, Ziegenhain, Christoph, Högstrand, Kari, Seki, Masafumi, Brennan, Margs S., Lehander, Madeleine, Wu, Bishan, Meng, Yiran, Markljung, Ellen, Norfo, Ruggiero, Ishida, Hisashi, Belander Strålin, Karin, Grasso, Francesca, Simoglou Karali, Christina, Aliouat, Affaf, Hillen, Amy, Chari, Edwin, Siletti, Kimberly, Thongjuea, Supat, Mead, Adam J., Linnarsson, Sten, Nerlov, Claus, Sandberg, Rickard, Yoshizato, Tetsuichi, Woll, Petter S., Jacobsen, Sten Eirik W.

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3028 – LINEAGE BIASED HEMATOPOIETIC STEM CELLS AT TIME OF BIRTH von Strålin, Karin Belander, Carrelha, Joana, Kettyle, Laura, Hillen, Amy, Högstrand, Kari, Markljung, Ellen, Grasso, Francesca, Seki, Masafumi, Mazzi, Stefania, Meng, Yiran, Wu, Bishan, Chari, Edwin, Lehander, Madeleine, Woll, Petter, Jacobsen, Sten Eirik

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Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells von Belander Strålin, Karin, Carrelha, Joana, Winroth, Axel, Ziegenhain, Christoph, Hagemann-Jensen, Michael, Kettyle, Laura M., Hillen, Amy, Högstrand, Kari, Markljung, Ellen, Grasso, Francesca, Seki, Masafumi, Mazzi, Stefania, Meng, Yiran, Wu, Bishan, Chari, Edwin, Lehander, Madeleine, Sandberg, Rickard, Woll, Petter S., Jacobsen, Sten Eirik W.

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Dual role of EZH2 in megakaryocyte differentiation von Mazzi, Stefania, Dessen, Philippe, Vieira, Mathieu, Dufour, Virginie, Cambot, Marie, El Khoury, Mira, Antony-Debré, Iléana, Arkoun, Brahim, Basso-Valentina, Francesca, BenAbdoulahab, Salwa, Edmond, Valerie, Rameau, Philippe, Petermann, Rachel, Wittner, Monika, Cassinat, Bruno, Plo, Isabelle, Debili, Najet, Raslova, Hana, Vainchenker, William

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T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes von Ali, Muhammad, Giannakopoulou, Eirini, Li, Yingqian, Lehander, Madeleine, Virding Culleton, Stina, Yang, Weiwen, Knetter, Cathrine, Odabasi, Mete Can, Bollineni, Ravi Chand, Yang, Xinbo, Foldvari, Zsofia, Böschen, Maxi-Lu, Taraldsrud, Eli, Strønen, Erlend, Toebes, Mireille, Hillen, Amy, Mazzi, Stefania, de Ru, Arnoud H., Janssen, George M. C., Kolstad, Arne, Tjønnfjord, Geir Erland, Lie, Benedicte A., Griffioen, Marieke, Lehmann, Sören, Osnes, Liv Toril, Buechner, Jochen, Garcia, K. Christopher, Schumacher, Ton N., van Veelen, Peter A., Leisegang, Matthias, Jacobsen, Sten Eirik W., Woll, Petter, Olweus, Johanna

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model von Arkoun, Brahim, Robert, Elie, Boudia, Fabien, Mazzi, Stefania, Dufour, Virginie, Siret, Aurélie, Mammasse, Yasmine, Aid, Zakia, Vieira, Matthieu, Aygun, Imanci, Aglave, Marine, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Hermine, Olivier, Droin, Nathalie, Debili, Najet, Plo, Isabelle, Malinge, Sébastien, Soler, Eric, Raslova, Hana, Mercher, Thomas, Vainchenker, William

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Study of the role of the methyltransferase EZH2 in normal and pathological megakaryopoiesis von Mazzi, Stefania

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Modeling Acute Megakaryoblastic Leukemia of Down Syndrome Using Induced Pluripotent Stem Cells von Arkoun, Brahim, Dufour, Virginie, Siret, Aurélie, Mazzi, Stefania, Mammasse, Yasmine, Vieira, Mathieu, Boudia, Fabien, Robert, Elie, Aid, Zakia, Cambot, Marie, Petermann, Rachel, Souquere, Sylvie, Rameau, Philippe, Catelain, Cyril, Diot, Romain, Tachdjian, Gérard, Debili, Najet, Plo, Isabelle, Raslova, Hana, Malinge, Sebastien, Soler, Eric, Mercher, Thomas, Vainchenker, William

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A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo von Giannakopoulou, Eirini, Lehander, Madeleine, Virding Culleton, Stina, Yang, Weiwen, Li, Yingqian, Karpanen, Terhi, Yoshizato, Tetsuichi, Rustad, Even H, Nielsen, Morten Milek, Bollineni, Ravi Chand, Tran, Trung T, Delic-Sarac, Marina, Gjerdingen, Thea Johanne, Douvlataniotis, Karolos, Laos, Maarja, Ali, Muhammad, Hillen, Amy, Mazzi, Stefania, Chin, Desmond Wai Loon, Mehta, Adi, Holm, Jeppe Sejerø, Bentzen, Amalie Kai, Bill, Marie, Griffioen, Marieke, Gedde-Dahl, Tobias, Lehmann, Sören, Jacobsen, Sten Eirik W, Woll, Petter S, Olweus, Johanna

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Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model von Brahim Arkoun, Elie Robert, Fabien Boudia, Stefania Mazzi, Virginie Dufour, Aurélie Siret, Yasmine Mammasse, Zakia Aid, Matthieu Vieira, Aygun Imanci, Marine Aglave, Marie Cambot, Rachel Petermann, Sylvie Souquere, Philippe Rameau, Cyril Catelain, Romain Diot, Gérard Tachdjian, Olivier Hermine, Nathalie Droin, Najet Debili, Isabelle Plo, Sébastien Malinge, Eric Soler, Hana Raslova, Thomas Mercher, William Vainchenker

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A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo von Giannakopoulou, Eirini Chrysovalantou, Lehander, Madeleine, Virding Culleton, Stina, Yang, Weiwen, Li, Yingqian, Kärpänen, Terhi Hannele, Yoshizato, Tetsuichi, Rustad, Even Holth, Nielsen, Morten Milek, Bollineni, Ravi Chand, Tran, Trung, Delic-Sarac, Marina, Gjerdingen, Thea Johanne, Douvlataniotis, Dimitrios Karolos, Laos, Maarja, Hillen, Amy, Ali, Muhammad, Mazzi, Stefania, Chin, Desmond Wai Loon, Mehta, Adi, Holm, Jeppe Sejerø, Bentzen, Amalie Kai, Bill, Marie, Griffioen, Marieke, Gedde-Dahl, Tobias, Lehmann, Sören, Jacobsen, Sten Eirik W., Woll, Petter S., Olweus, Johanna

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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner von Luis, Tiago C, Barkas, Nikolaos, Carrelha, Joana, Giustacchini, Alice, Mazzi, Stefania, Norfo, Ruggiero, Wu, Bishan, Aliouat, Affaf, Guerrero, Jose A, Rodriguez-Meira, Alba, Bouriez-Jones, Tiphaine, Macaulay, Iain C, Jasztal, Maria, Zhu, Guangheng, Ni, Heyu, Robson, Matthew J, Blakely, Randy D, Mead, Adam J, Nerlov, Claus, Ghevaert, Cedric, Jacobsen, Sten Eirik W

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