A New Venue of TNF Targeting von Steeland, Sophie, Libert, Claude, Vandenbroucke, Roosmarijn E

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Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease von Steeland, Sophie, Gorlé, Nina, Vandendriessche, Charysse, Balusu, Sriram, Brkic, Marjana, Van Cauwenberghe, Caroline, Van Imschoot, Griet, Van Wonterghem, Elien, De Rycke, Riet, Kremer, Anneke, Lippens, Saskia, Stopa, Edward, Johanson, Conrad E, Libert, Claude, Vandenbroucke, Roosmarijn E

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TNFR1 inhibition with a Nanobody protects against EAE development in mice von Steeland, Sophie, Van Ryckeghem, Sara, Van Imschoot, Griet, De Rycke, Riet, Toussaint, Wendy, Vanhoutte, Leen, Vanhove, Christian, De Vos, Filip, Vandenbroucke, Roosmarijn E., Libert, Claude

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A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice von Vandewalle, Jolien, Steeland, Sophie, Van Ryckeghem, Sara, Eggermont, Melanie, Van Wonterghem, Elien, Vandenbroucke, Roosmarijn E, Libert, Claude

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Long-term safety, tolerability, and efficacy of efgartigimod (ADAPT+): interim results from a phase 3 open-label extension study in participants with generalized myasthenia gravis von Howard, Jr, James F, Bril, Vera, Vu, Tuan, Karam, Chafic, Peric, Stojan, De Bleecker, Jan L, Murai, Hiroyuki, Meisel, Andreas, Beydoun, Said R, Pasnoor, Mamatha, Guglietta, Antonio, Van Hoorick, Benjamin, Steeland, Sophie, T'joen, Caroline, Utsugisawa, Kimiaki, Verschuuren, Jan, Mantegazza, Renato

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Nanobodies as therapeutics: big opportunities for small antibodies von Steeland, Sophie, Vandenbroucke, Roosmarijn E., Libert, Claude

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Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer's disease puzzle von Steeland, Sophie, Vandenbroucke, Roosmarijn

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Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1 von Puimège, Leen, Van Hauwermeiren, Filip, Steeland, Sophie, Van Ryckeghem, Sara, Vandewalle, Jolien, Lodens, Sofie, Dejager, Lien, Vandevyver, Sofie, Staelens, Jan, Timmermans, Steven, Vandenbroucke, Roosmarijn E, Libert, Claude

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Choroid plexus tumor necrosis factor receptor 1 : a new neuroinflammatory piece of the complex Alzheimer's disease puzzle von Steeland, Sophie, Vandenbroucke, Roosmarijn

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Long-term Safety, Tolerability, and Efficacy of Subcutaneous Efgartigimod PH20 in Participants with Generalized Myasthenia Gravis: Interim Results of the ADAPT-SC+ Study (P10-11.00... von Howard, James, Li, Yuebing, Vu, Tuan, Korobko, Denis, Steeland, Sophie, Van Hoorick, Benjamin, Podhorna, Jana, Hodari, Moana, Utsugisawa, Kimiaki, Sacca, Francesco, Wiendl, Heinz, De Bleecker, Jan, Mantegazza, Renato

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A new venue of TNF targeting von Steeland, Sophie, Libert, Claude, Vandenbroucke, Roosmarijn

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Generation and Characterization of Small Single Domain Antibodies Inhibiting Human Tumor Necrosis Factor Receptor 1 von Steeland, Sophie, Puimège, Leen, Vandenbroucke, Roosmarijn E., Van Hauwermeiren, Filip, Haustraete, Jurgen, Devoogdt, Nick, Hulpiau, Paco, Leroux-Roels, Geert, Laukens, Debby, Meuleman, Philip, De Vos, Martine, Libert, Claude

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Long-Term Safety, Tolerability, and Efficacy of Subcutaneous Efgartigimod PH20 in Patients with Generalized Myasthenia Gravis: Interim Results of the ADAPT-SC+ Study (P1-5.014) von Howard, James, Li, George, Vu, Tuan, Korobko, Denis, Smilowski, Marek, Liu, Li, Steeland, Sophie, Noukens, Jan, Van Hoorick, Benjamin, Podhorna, Jana, Li, Yuebing, Utsugisawa, Kimiaki, Sacca, Francesco, Wiendl, Heinz, De Bleecker, Jan, Mantegazza, Renato

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Dose Selection and Clinical Development of Efgartigimod PH20 Subcutaneous in Patients with Generalized Myasthenia Gravis (P1-5.017) von Li, George, Li, Yuebing, Vu, Tuan, Korobko, Denis, Smilowski, Marek, Liu, Li, Steeland, Sophie, Van Hoorick, Benjamin, Podhorna, Jana, Casey, Jenna, Noukens, Jan, Van Bragt, Tonke, Utsugisawa, Kimiaki, Wiendl, Heinz, De Bleecker, Jan, Mantegazza, Renato, Howard, James

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Efgartigimod demonstrates consistent improvements in patients with generalized myasthenia gravis regardless of prior treatment failures von Siddiqi, Zaeem, Rozsa, Csilla, Saccá, Francesco, De Bleecker, Jan L., Verschuuren, Jan, Hoffmann, Sarah, Vu, Tuan, Bril, Vera, Murai, Hiroyuki, Brauer, Edward, Kerstens, René, Steeland, Sophie, Ulrichts, Peter, Goyal, Neelam, Vissing, John, Mantegazza, Renato, Howard, James F.

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Subcutaneous efgartigimod PH20 in generalized myasthenia gravis: A phase 3 randomized noninferiority study (ADAPT-SC) and interim analyses of a long-term open-label extension study... von Howard, James F., Vu, Tuan, Li, George, Korobko, Denis, Smilowski, Marek, Liu, Li, Gistelinck, Fien, Steeland, Sophie, Noukens, Jan, Van Hoorick, Benjamin, Podhorna, Jana, Borgions, Filip, Li, Yuebing, Utsugisawa, Kimiaki, Wiendl, Heinz, De Bleecker, Jan L., Mantegazza, Renato

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Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis von Steeland, Sophie, Van Ryckeghem, Sara, Vandewalle, Jolien, Ballegeer, Marlies, Van Wonterghem, Elien, Eggermont, Melanie, Decruyenaere, Johan, De Bus, Liesbet, Libert, Claude, Vandenbroucke, Roosmarijn E.

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Topical imiquimod yields systemic effects due to unintended oral uptake von Grine, Lynda, Steeland, Sophie, Van Ryckeghem, Sara, Ballegeer, Marlies, Lienenklaus, Stefan, Weiss, Siegfried, Sanders, Niek N., Vandenbroucke, Roosmarijn E., Libert, Claude

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A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice von Vandewalle, Jolien, Steeland, Sophie, Van Ryckeghem, Sara, Eggermont, Melanie, Van Wonterghem, Elien, Vandenbroucke, Roosmarijn, Libert, Claude

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Development and Validation of a Small Single-domain Antibody That Effectively Inhibits Matrix Metalloproteinase 8 von Demeestere, Delphine, Dejonckheere, Eline, Steeland, Sophie, Hulpiau, Paco, Haustraete, Jurgen, Devoogdt, Nick, Wichert, Rielana, Becker-Pauly, Christoph, Van Wonterghem, Elien, Dewaele, Sylviane, Van Imschoot, Griet, Aerts, Jeroen, Arckens, Lutgarde, Saeys, Yvan, Libert, Claude, Vandenbroucke, Roosmarijn E

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