Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release von Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali

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1361 Neoadjuvant CD40 agonism remodels the tumor immune microenvironment in locally advanced esophageal/gastroesophageal junction cancer von Keenan, Bridget P, Soto, Maira, Filbert, Erin L, Yang, Hai, Starzinski, Stephanie, Starzinski, Alec, Gin, Marissa, Chen, Brandon, Le, Phi, Li, Tony, Bol, Brandon, Cheung, Alexander, Zhang, Li, Hsu, Frank J, Ko, Andrew H, Fong, Lawrence

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548 Evolution of myeloid-mediated mechanisms of immunotherapy resistance at single-cell resolution with human prostate cancer progression von Lyu, Aram, Fan, Zenghua, Luong, Diamond, Setayesh, Ali, Starzinski, Alec, Allen, Eliezer Van, Fong, Lawrence

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862 TLR9 agonism promotes cytotoxic T cell persistence and myeloid remodeling when combined with radiation therapy and PD-1 blockade in oligometastatic prostate cancer patients von Fan, Zenghua, Oh, David Y, Wong, Anthony, Shinohara, Katsuto, Nguyen, Hao, Hwang, Caleb, Chang, Hewitt, Starzinski, Alec, Li, Tony, Leon, Christopher De, Gin, Marissa, Allen, Eliezer Van, Zhang, Li, Aggarwal, Rahul R, Friedlander, Terence W, Small, Eric J, Feng, Felix Y, Fong, Lawrence

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Use of high-dimensional and spatial immune profiling to explore sotigalimab (CD40 agonist) activation of antigen presenting cells and T cells in the tumor microenvironment in patie... von Soto, Maira, Filbert, Erin L, Yang, Hai, Zhang, Li, Starzinski, Stephanie, Starzinski, Alec, Cheung, Alexander, Li, Tony, Hsu, Frank J., Ko, Andrew H., Fong, Lawrence, Keenan, Bridget P

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Effect of modulation of CD3 binding in a PSMAxCD3 T-cell engaging bispecific antibody on maintenance of efficient tumor cell kill and cytokine release von Buelow, Ben, Dang, Kevin, Dalvi, Pranjali, Li, Yuping, Cheung, Alexander, Rancan, Chiara, Sankaran, Preethi, Pham, Duy, Harris, Katherine, Davison, Laura, Balasubramani, Aarti, Clarke, Starlynn, Starzinski, Alec, Fong, Lawrence, Iyer, Suhasini

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Neoadjuvant CD40 Agonism Remodels the Tumor Immune Microenvironment in Locally Advanced Esophageal/Gastroesophageal Junction Cancer von Soto, Maira, Filbert, Erin L, Yang, Hai, Starzinski, Stephanie, Starzinski, Alec, Gin, Marissa, Chen, Brandon, Le, Phi, Li, Tony, Bol, Brandon, Cheung, Alexander, Zhang, Li, Hsu, Frank J, Ko, Andrew, Fong, Lawrence, Keenan, Bridget P

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CD4+ CAR T-cell exhaustion associated with early relapse of multiple myeloma after BCMA CAR T-cell therapy von Ledergor, Guy, Fan, Zenghua, Wu, Kai, McCarthy, Elizabeth, Hyrenius-Wittsten, Axel, Starzinski, Alec, Chang, Hewitt, Bridge, Mark, Kwek, Serena, Cheung, Alexander, Bylsma, Sophia, Hansen, Erik, Wolf, Jeffrey, Wong, Sandy, Shah, Nina, Roybal, Kole T., Martin, Thomas, Ye, Chun J., Fong, Lawrence

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