alpha.-Melanotropin: the minimal active sequence in the frog skin bioassay von Hruby, Victor J, Wilkes, Brian C, Hadley, Mac E, Al-Obeidi, Fahad, Sawyer, Tomi K, Staples, Douglas J, DeVaux, Ann E, Dym, Orin, Castrucci, Ana Maria de L

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Synthesis of a Series of Stromelysin-Selective Thiadiazole Urea Matrix Metalloproteinase Inhibitors von Jacobsen, E. Jon, Mitchell, Mark A, Hendges, Susan K, Belonga, Kenneth L, Skaletzky, Louis L, Stelzer, Lindsay S, Lindberg, Thomas. J, Fritzen, Edward L, Schostarez, Heinrich J, O'Sullivan, Theresa J, Maggiora, Linda L, Stuchly, Christopher W, Laborde, Alice L, Kubicek, Marc F, Poorman, Roger A, Beck, Joan M, Miller, Henry R, Petzold, Gary L, Scott, Pam S, Truesdell, Scott E, Wallace, Tanya L, Wilks, John W, Fisher, Christopher, Goodman, Linda V, Kaytes, Paul S, Ledbetter, Stephen R, Powers, Elaine A, Vogeli, Gabriel, Mott, John E, Trepod, Catherine M, Staples, Douglas J, Baldwin, Eric T, Finzel, Barry C

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Substrate analog inhibition and active site titration of purified recombinant HIV-1 protease von Tomasselli, Alfredo G, Olsen, Mary K, Hui, John O, Staples, Douglas J, Sawyer, Tomi K, Heinrikson, Robert L, Tomich, Che Shen C

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Truncation studies of α-melanotropin peptides identify tripeptide analogues exhibiting prolonged agonist bioactivity von Haskell-Luevano, Carrie, Sawyer, Tomi K., Hendrata, Siska, North, Cheryl, Panahinia, Laila, Stum, Martha, Staples, Douglas J., De Lauro Castrucci, Anna M., Hadley, Mac E., Hruby, Victor J.

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Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe... von Sawyer, Tomi K, Pals, Donald T, Mao, Boryeu, Staples, Douglas J, DeVaux, Anne E, Maggiora, Linda L, Affholter, Joseph A, Kati, Warren, Duchamp, David

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Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2 von Tomasselli, A G, Hui, J O, Sawyer, T K, Staples, D J, Bannow, C, Reardon, I M, Howe, W J, DeCamp, D L, Craik, C S, Heinrikson, R L

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Identification of a C-terminal cdc25 sequence required for promotion of germinal vesicle breakdown von POWERS, Elaine A., THOMPSON, David P., GARNER-HAMRICK, Peggy A., HE, Wanxia, YEM, Anthony W., BANNOW, Carol A., STAPLES, Douglas J., WASZAK, Gregory A., SMITH, Clark W., DEIBEL, Martin R., FISHER, Chris

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Identification of a C-terminal cdc25 sequence required for promotion of germinal vesicle breakdown von Powers, E A, Thompson, D P, Garner-Hamrick, P A, He, W, Yem, A W, Bannow, C A, Staples, D J, Waszak, G A, Smith, C W, Deibel, Jr, M R, Fisher, C

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Comparative Biological Activities of α-MSH Antagonists in Vertebrate Pigment Cells von Castrucci, Ana Maria de L., Almeida, Ana Luisa K., Al-Obeidi, Fahad A., Hadley, Mac E., Hruby, Victor J., Staples, Douglas J., Sawyer, Tomi K.

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Structure-activity relationships of [Nle4, D-Phe7]alpha-MSH. Discovery of a tripeptidyl agonist exhibiting sustained bioactivity von Sawyer, T K, Castrucci, A M, Staples, D J, Affholter, J A, De Vaux, A, Hruby, V J, Hadley, M E

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Interdomain hydrolysis of a truncated Pseudomonas exotoxin by the human immunodeficiency virus-1 protease von TOMASSELLI, A. G, HUI, J. O, SAWYER, T. K, STAPLES, D. J, FITZGERALD, D. J, CHAUDHARY, V. K, PASTAN, I, HEINRIKSON, R. L

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α-Melanocyte stimulating hormone message and inhibitory sequences: Comparative structure-activity studies on melanocytes von Sawyer, Tomi K., Staples, Douglas J., Castrucci, Ana M.L., Hadley, Mac E., Al-Obeidi, Fahad A., Cody, Wayne L., Hruby, Victor J.

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Structure-Activity Relationships of [Nle4, D-Phe7]α-MSH von SAWYER, TOMI K., CASTRUCCI, ANA M., STAPLES, DOUGLAS J., AFFHOLTER, JOSEPH A., DE VAUX, ANNE E., HRUBY, VICTOR J., HADLEY, MAC E.

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Discovery of an α-melanotropin antagonist effective in vivo von Castrucci, Ana Maria de L., Sherbrooke, Wade C., Sawyer, Tomi K., Staples, Douglas J., Tuma, Maria Carolina B., Hadley, Mac E.

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Proteases from human immunodeficiency virus and avian myeloblastosis virus show distinct specificities in hydrolysis of multidomain protein substrates von TOMASSELLI, A. G, HUI, J. O, HEINRIKSON, R. L, SAWYER, T. K, STAPLES, D. J, BANNOW, C. A, REARDON, I. M, CHAUDHARY, V. K, FRYLING, C. M, PASTAN, I, FITZGERALD, D. J

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Structure-conformation-activity relationships of renin inhibitory peptides having P1-P1' Xaaψ[CH2NH]Yaa substitutions: molecular modeling and crystallography studies1 von Sawyer, Tomi K., Pals, Donald T., Mao, Boryeu, Maggiora, Linda L., Staples, Douglas J., deVaux, Anne E., Schostarez, Heinrich J., Kinner, John H., Smith, Clark W.

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Structure-conformation-activity relationships of renin inhibitory peptides having P 1-P 1' Xaaψ[CH 2NH]Yaa substitutions: molecular modeling and crystallography studies 1 von Sawyer, Tomi K., Pals, Donald T., Mao, Boryeu, Maggiora, Linda L., Staples, Douglas J., deVaux, Anne E., Schostarez, Heinrich J., Kinner, John H., Smith, Clark W.

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Effect on protein phosphatase activity of peptide backbone modification and truncation of the autoinhibitory domain peptide of calcineurin von BANNOW, CAROL A., STAPLES, DOUGLAS J., SMITH, CLARK W., CHAPMAN, DARRYL L., LEACH, KAREN L.

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α-Melanocyte-stimulating hormone structure-activity studies: Comparative analysis of melanotropic and CNS bioactivities von Sawyer, Tomi K., Hadley, Mac E., Hruby, Victor J., de Lauro Castrucci, Ana Maria, Staples, Douglas J., Farah, John, L. O'donohue, Thomas

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HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs von SAWYER, TOMI K., STAPLES, DOUGLAS J., LIU, LI, TOMASSELLI, ALFREDO G., HUI, JOHN O., O'CONNELL, KATHY, SCHOSTAREZ, HEINRICH, HESTER, JACKSON B., MOON, JOSEPH, HOWE, W. JEFFREY, SMITH, CLARCK W., DECAMP, DIANNE L., CRAIK, CHARLES S., DUNN, BEN M., LOWTHER, W. TODD, HARRIS, JESSICA, POORMAN, ROGER A., WLODAWER, ALEXANDER, JASKOLSKI, MARIUSZ, HEINRIKSON, ROBERT L.

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