RAS, wanted dead or alive: Advances in targeting RAS mutant cancers von Stalnecker, Clint A., Der, Channing J.

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KRAS regulation of miRNA: Stepping on the brake to go faster von Stalnecker, Clint A., Der, Channing J.

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SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis von Greene, Kai Su, Lukey, Michael J., Wang, Xueying, Blank, Bryant, Druso, Joseph E., Lin, Miao-chong J., Stalnecker, Clint A., Zhang, Chengliang, Abril, Yashira Negrón, Erickson, Jon W., Wilson, Kristin F., Lin, Hening, Weiss, Robert S., Cerione, Richard A.

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Susceptibility to autophagy inhibition is enhanced by dual IGF1R and MAPK/ERK inhibition in pancreatic cancer von Stalnecker, Clint A., Coleman, Michael F., Bryant, Kirsten L.

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Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in transformed cells von Stalnecker, Clint A., Ulrich, Scott M., Li, Yunxing, Ramachandran, Sekar, McBrayer, Mary Kate, DeBerardinis, Ralph J., Cerione, Richard A., Erickson, Jon W.

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Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer von Goodwin, Craig M, Waters, Andrew M, Klomp, Jennifer E, Javaid, Sehrish, Bryant, Kirsten L, Stalnecker, Clint A, Drizyte-Miller, Kristina, Papke, Bjoern, Yang, Runying, Amparo, Amber M, Ozkan-Dagliyan, Irem, Baldelli, Elisa, Calvert, Valerie, Pierobon, Mariaelena, Sorrentino, Jessica A, Beelen, Andrew P, Bublitz, Natalie, Lüthen, Mareen, Wood, Kris C, Petricoin, Emanuel F, Sers, Christine, McRee, Autumn J, Cox, Adrienne D, Der, Channing J

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Concurrent Inhibition of IGF1R and ERK Increases Pancreatic Cancer Sensitivity to Autophagy Inhibitors von Stalnecker, Clint A, Grover, Kajal R, Edwards, A Cole, Coleman, Michael F, Yang, Runying, DeLiberty, Jonathan M, Papke, Björn, Goodwin, Craig M, Pierobon, Mariaelena, Petricoin, Emanuel F, Gautam, Prson, Wennerberg, Krister, Cox, Adrienne D, Der, Channing J, Hursting, Stephen D, Bryant, Kirsten L

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Conformational changes in the activation loop of mitochondrial glutaminase C: A direct fluorescence readout that distinguishes the binding of allosteric inhibitors from activators von Stalnecker, Clint A., Erickson, Jon W., Cerione, Richard A.

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Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer von Klomp, Jennifer E, Diehl, J Nathaniel, Klomp, Jeffrey A, Edwards, A Cole, Yang, Runying, Morales, Alexis J, Taylor, Khalilah E, Drizyte-Miller, Kristina, Bryant, Kirsten L, Schaefer, Antje, Johnson, Jared L, Huntsman, Emily M, Yaron, Tomer M, Pierobon, Mariaelena, Baldelli, Elisa, Prevatte, Alex W, Barker, Natalie K, Herring, Laura E, Petricoin, 3rd, Emanuel F, Graves, Lee M, Cantley, Lewis C, Cox, Adrienne D, Der, Channing J, Stalnecker, Clint A

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The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled von Li, Yunxing, Ramachandran, Sekar, Nguyen, Thuy-Tien T., Stalnecker, Clint A., Cerione, Richard A., Erickson, Jon W.

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Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers von Klomp, Jeffrey A, Klomp, Jennifer E, Stalnecker, Clint A, Bryant, Kirsten L, Edwards, A Cole, Drizyte-Miller, Kristina, Hibshman, Priya S, Diehl, J Nathaniel, Lee, Ye S, Morales, Alexis J, Taylor, Khalilah E, Peng, Sen, Tran, Nhan L, Herring, Laura E, Prevatte, Alex W, Barker, Natalie K, Hover, Laura D, Hallin, Jill, Chowdhury, Saikat, Coker, Oluwadara, Lee, Hey Min, Goodwin, Craig M, Gautam, Prson, Olson, Peter, Christensen, James G, Shen, John P, Kopetz, Scott, Graves, Lee M, Lim, Kian-Huat, Wang-Gillam, Andrea, Wennerberg, Krister, Cox, Adrienne D, Der, Channing J

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Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS von Li, Yunxing, Erickson, Jon W, Stalnecker, Clint A, Katt, William P, Huang, Qingqiu, Cerione, Richard A, Ramachandran, Sekar

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The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled von Li, Yunxing, Ramachandran, Sekar, Nguyen, Thuy-Tien T., Stalnecker, Clint A., Cerione, Richard A., Erickson, Jon W.

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CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment von Klomp, Jennifer E., Lee, Ye S., Goodwin, Craig M., Papke, Bjorn, Klomp, Jeff A., Waters, Andrew M., Stalnecker, Clint A., DeLiberty, Jonathan M., Drizyte-Miller, Kristina, Yang, Runying, Diehl, J. Nathaniel, Yin, Hongwei H., Pierobon, Mariaelena, Baldelli, Elisa, Ryan, Meagan B., Li, Siqi, Peterson, Jackson, Smith, Amber R., Neal, James T., McCormick, Aaron K., Kuo, Calvin J., Counter, Christopher M., Petricoin, Emanuel F., Cox, Adrienne D., Bryant, Kirsten L., Der, Channing J.

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VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS -mutant pancreatic cancer von Lee, Ye S, Klomp, Jennifer E, Stalnecker, Clint A, Goodwin, Craig M, Gao, Yanzhe, Droby, Gaith N, Vaziri, Cyrus, Bryant, Kirsten L, Der, Channing J, Cox, Adrienne D

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Detection of phenotype‐specific therapeutic vulnerabilities in breast cells using a CRISPR loss‐of‐function screen von Barkovskaya, Anna, Goodwin, Craig M., Seip, Kotryna, Hilmarsdottir, Bylgja, Pettersen, Solveig, Stalnecker, Clint, Engebraaten, Olav, Briem, Eirikur, Der, Channing J., Moestue, Siver A., Gudjonsson, Thorarinn, Mælandsmo, Gunhild M., Prasmickaite, Lina

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Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer von Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.

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Balancing redox stress: anchorage-independent growth requires reductive carboxylation von Stalnecker, Clint A., Cluntun, Ahmad A., Cerione, Richard A.

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Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer von Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.

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Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism von Huang, Qingqiu, Stalnecker, Clint, Zhang, Chengliang, McDermott, Lee A., Iyer, Prema, O’Neill, Jason, Reimer, Shawn, Cerione, Richard A., Katt, William P.

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