TREM2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant von Thornton, Peter, Sevalle, Jean, Deery, Michael J, Fraser, Graham, Zhou, Ye, Ståhl, Sara, Franssen, Elske H, Dodd, Roger B, Qamar, Seema, Gomez Perez‐Nievas, Beatriz, Nicol, Louise SC, Eketjäll, Susanna, Revell, Jefferson, Jones, Clare, Billinton, Andrew, St George‐Hyslop, Peter H, Chessell, Iain, Crowther, Damian C

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Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis von Zhao, Yingjun, Tseng, I-Chu, Heyser, Charles J., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Zheng, Qiuyang, Huang, Timothy, Wang, Xin, Arslan, Pharhad E., Chakrabarty, Paramita, Wu, Chengbiao, Bu, Guojun, Mobley, William C., Zhang, Yun-wu, St. George-Hyslop, Peter, Masliah, Eliezer, Fraser, Paul, Xu, Huaxi

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Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2 von Volkmar, Norbert, Gawden‐Bone, Christian M, Williamson, James C, Nixon‐Abell, Jonathon, West, James A, St George‐Hyslop, Peter H, Kaser, Arthur, Lehner, Paul J

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Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related mice von Audrain, Mickael, Haure‐Mirande, Jean‐Vianney, Mleczko, Justyna, Wang, Minghui, Griffin, Jennifer K., St George‐Hyslop, Peter H., Fraser, Paul, Zhang, Bin, Gandy, Sam, Ehrlich, Michelle E.

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MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease von Li, Siwen, Poon, Chi Him, Zhang, Zhigang, Yue, Ming, Chen, Ruijun, Zhang, Yalun, Hossain, Md. Farhad, Pan, Yining, Zhao, Jun, Rong, Lei, Chu, Leung Wing, Shea, Yat Fung, Rogaeva, Ekaterina, Tu, Jie, St George‐Hyslop, Peter, Lim, Lee Wei, Song, You‐Qiang

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SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk von Reitz, Christiane, Tokuhiro, Shinya, Clark, Lorraine N., Conrad, Christopher, Vonsattel, Jean-Paul, Hazrati, Lili-Naz, Palotás, András, Lantigua, Raphael, Medrano, Martin, Z. Jiménez -Velázquez, Ivonne, Vardarajan, Badri, Simkin, Irene, Haines, Jonathan L., Pericak -Vance, Margaret A., Farrer, Lindsay A., Lee, Joseph H., Rogaeva, Ekaterina, George- Hyslop, Peter St, Mayeux, Richard

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Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions von Krainer, Georg, Welsh, Timothy J., Joseph, Jerelle A., Espinosa, Jorge R., Wittmann, Sina, de Csilléry, Ella, Sridhar, Akshay, Toprakcioglu, Zenon, Gudiškytė, Giedre, Czekalska, Magdalena A., Arter, William E., Guillén-Boixet, Jordina, Franzmann, Titus M., Qamar, Seema, George-Hyslop, Peter St, Hyman, Anthony A., Collepardo-Guevara, Rosana, Alberti, Simon, Knowles, Tuomas P. J.

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Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome von Masellis, Mario, Momeni, Parastoo, Meschino, Wendy, Heffner, Reid, Elder, Joshua, Sato, Christine, Liang, Yan, George-Hyslop, Peter St, Hardy, John, Bilbao, Juan, Black, Sandra, Rogaeva, Ekaterina

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The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease von Harwood, Dylan G., Kalechstein, Ari, Barker, Warren W., Strauman, Silvia, St. George-Hyslop, Peter, Iglesias, Casandra, Loewenstein, David, Duara, Ranjan

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TREM2 Variants in Alzheimer's Disease von Guerreiro, Rita, Wojtas, Aleksandra, Bras, Jose, Carrasquillo, Minerva, Rogaeva, Ekaterina, Majounie, Elisa, Cruchaga, Carlos, Sassi, Celeste, Kauwe, John S.K, Younkin, Steven, Hazrati, Lilinaz, Collinge, John, Pocock, Jennifer, Lashley, Tammaryn, Williams, Julie, Lambert, Jean-Charles, Amouyel, Philippe, Goate, Alison, Rademakers, Rosa, Morgan, Kevin, Powell, John, St. George-Hyslop, Peter, Singleton, Andrew, Hardy, John

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Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets von Ramos, Jairo, Caywood, Laura J., Prough, Michael B., Clouse, Jason E., Herington, Sharlene D., Slifer, Susan H., Fuzzell, M. Denise, Fuzzell, Sarada L., Hochstetler, Sherri D., Miskimen, Kristy L., Main, Leighanne R., Osterman, Michael D., Zaman, Andrew F., Whitehead, Patrice L., Adams, Larry D., Laux, Renee A., Song, Yeunjoo E., Foroud, Tatiana M., Mayeux, Richard P., St. George‐Hyslop, Peter, Ogrocki, Paula K., Lerner, Alan J., Vance, Jeffery M., Cuccaro, Michael L., Haines, Jonathan L., Pericak‐Vance, Margaret A., Scott, William K.

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The in Vivo Brain Interactome of the Amyloid Precursor Protein von Bai, Yu, Markham, Kelly, Chen, Fusheng, Weerasekera, Rasanjala, Watts, Joel, Horne, Patrick, Wakutani, Yosuke, Bagshaw, Rick, Mathews, Paul M., Fraser, Paul E., Westaway, David, St. George-Hyslop, Peter, Schmitt-Ulms, Gerold

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Immunotherapy for Alzheimer's Disease von Gelinas, David S., DaSilva, Kevin, Fenili, Daniela, St. George-Hyslop, Peter, McLaurin, JoAnne

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Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation von Hague, Stephen, Rogaeva, Ekaterina, Hernandez, Dena, Gulick, Cindy, Singleton, Amanda, Hanson, Melissa, Johnson, Janel, Weiser, Roberto, Gallardo, Marisol, Ravina, Bernard, Gwinn-Hardy, Katrina, Crawley, Anthony, St. George-Hyslop, Peter H., Lang, Anthony E., Heutink, Peter, Bonifati, Vincenzo, Hardy, John, Singleton, Andrew

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Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining von Zhang, Ming, Schmitt-Ulms, Gerold, Sato, Christine, Xi, Zhengrui, Zhang, Yalun, Zhou, Ye, St George-Hyslop, Peter, Rogaeva, Ekaterina

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Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis von Yang, Dun-Sheng, Stavrides, Philip, Mohan, Panaiyur S., Kaushik, Susmita, Kumar, Asok, Ohno, Masuo, Schmidt, Stephen D., Wesson, Daniel W., Bandyopadhyay, Urmi, Jiang, Ying, Pawlik, Monika, Peterhoff, Corrinne M., Yang, Austin J., Wilson, Donald A., St. George-Hyslop, Peter, Westaway, David, Mathews, Paul M., Levy, Efrat, Cuervo, Ana Maria, Nixon, Ralph A.

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Coding mutations in SORL1 and Alzheimer disease von Vardarajan, Badri N., Zhang, Yalun, Lee, Joseph H., Cheng, Rong, Bohm, Christopher, Ghani, Mahdi, Reitz, Christiane, Reyes-Dumeyer, Dolly, Shen, Yufeng, Rogaeva, Ekaterina, St George-Hyslop, Peter, Mayeux, Richard

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Molecular biology and genetics of Alzheimer's disease von St George-Hyslop, Peter H., Petit, Agnès

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Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein Pathology von Michel, Claire H., Kumar, Satish, Pinotsi, Dorothea, Tunnacliffe, Alan, St. George-Hyslop, Peter, Mandelkow, Eckhard, Mandelkow, Eva-Maria, Kaminski, Clemens F., Kaminski Schierle, Gabriele S.

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SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis von RUBINO, Elisa, RAINERO, Innocenzo, CECILIA BRUNI, Amalia, GEORGE-HYSLOP, Peter Henry St, SCARPINI, Elio, GALLONE, Salvatore, PINESSI, Lorenzo, CHIO, Adriano, ROGAEVA, Ekaterina, GALIMBERTI, Daniela, FENOGLIO, Pierpaola, GRINBERG, Yakov, ISAIA, Giancarlo, CALVO, Andrea, GENTILE, Salvatore

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