Cholesterol-lowering therapy evokes time-limited changes in serotonergic transmission von Vevera, Jan, Fišar, Zdenĕk, Kvasnička, Tomáš, Zdeněk, Hanuš, Stárková, Lucie, Češka, Richard, Papežová, Hana

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JE INTEGROVANA DENNI PECE ALTERNATIVOU KE KLASICKE PSYCHIATRICKE HOSPITALIZACI? von Howardová, Andrea, Raboch, Jirí, Cíhal, Libor, Stárková, Lucie

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Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort von Zaliova, Marketa, Stuchly, Jan, Winkowska, Lucie, Musilova, Alena, Fiser, Karel, Slamova, Martina, Starkova, Julia, Vaskova, Martina, Hrusak, Ondrej, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Trka, Jan

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PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase von Hlozkova, Katerina, Hermanova, Ivana, Safrhansova, Lucie, Alquezar-Artieda, Natividad, Kuzilkova, Daniela, Vavrova, Adela, Sperkova, Kristyna, Zaliova, Marketa, Stary, Jan, Trka, Jan, Starkova, Julia

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Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia von Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan

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ERG deletions in childhood acute lymphoblastic leukemia with DUX4 rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screeni... von Zaliova, Marketa, Potuckova, Eliska, Hovorkova, Lenka, Musilova, Alena, Winkowska, Lucie, Fiser, Karel, Stuchly, Jan, Mejstrikova, Ester, Starkova, Julia, Zuna, Jan, Stary, Jan, Trka, Jan

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P334: ULTIMATE CLARIFICATION OF THE RELATIONSHIP BETWEEN ASPARAGINE SYNTHETASE ACTIVITY AND SENSITIVITY OF LEUKEMIA TO L‐ASPARAGINASE von Hlozkova, Katerina, Hermanova, Ivana, Safrhansova, Lucie, Trka, Jan, Tennant, Daniel, Starkova, Julia

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Identification of Fusion Gene Breakpoints is Feasible and Facilitates Accurate Sensitive Minimal Residual Disease Monitoring on Genomic Level in Patients With PML‐RARA, CBFB‐MYH11,... von Lukes, Julius, Winkowska, Lucie, Zwyrtkova, Martina, Starkova, Julia, Sramkova, Lucie, Stary, Jan, Trka, Jan, Zuna, Jan, Zaliova, Marketa

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Frequency and prognostic impact of ZEB2 H1038 and 1072 mutations in childhood B-other acute lymphoblastic leukemia von Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan

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A novel class of ZNF384 aberrations in acute leukemia von Zaliova, Marketa, Winkowska, Lucie, Stuchly, Jan, Fiser, Karel, Triska, Petr, Zwyrtkova, Martina, Hrusak, Ondrej, Starkova, Julia, Sramkova, Lucie, Stary, Jan, Trka, Jan, Zuna, Jan

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Limited Therapeutical Impact of Extensive Genomic Profiling in Relapsed Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia: Population-Based Four-Year Consecutive Cohort von Zaliova, Marketa, Stuchly, Jan, Fiser, Karel, Musilova, Alena, Slamova, Martina, Winkowska, Lucie, Starkova, Julia, Mejstrikova, Ester, Zuna, Jan, Sramkova, Lucie, Stary, Jan, Trka, Jan

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Two novel fusion genes, AIF1L‐ETV6 and ABL1‐AIF1L, result together with ETV6‐ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin von Lukes Jr, Julius, Potuckova, Eliska, Sramkova, Lucie, Stary, Jan, Starkova, Julia, Trka, Jan, Votava, Felix, Zuna, Jan, Zaliova, Marketa

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Dissecting Childhood B-Other Acute Lymphoblastic Leukemia: Lower Frequency of Druggable Gene Fusions in European Population? von Zaliova, Marketa, Stuchly, Jan, Fiser, Karel, Musilova, Alena, Slamova, Martina, Winkowska, Lucie, Starkova, Julia, Vaskova, Martina, Zuna, Jan, Stary, Jan, Trka, Jan

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Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy von Alquezar-Artieda, Natividad, Kuzilkova, Daniela, Roberts, Jennie, Hlozkova, Katerina, Pecinova, Alena, Pecina, Petr, Zwyrtkova, Martina, Potuckova, Eliska, Kavan, Daniel, Hermanova, Ivana, Zaliova, Marketa, Novak, Petr, Mracek, Tomas, Sramkova, Lucie, Tennant, Daniel A., Trka, Jan, Starkova, Julia

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Molecular Background of BCP-ALL Cases with an Early Switch to Monocytic Lineage von Fier, Karel, Slámová, Lucie, Dobiáová, Alena, Starková, Júlia, Froňková, Eva, Aliová, Markéta, Polgárová, Kamila, Figueroa, Maria E, Kalina, Tomá, Zuna, Jan, Trka, Jan, Starý, Jan, Hruák, Ondřej, Mejstříková, Ester

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Epigenetic Status Of CEBPA Promoter and Expression Of CEBPα Correlates With Molecular Genetic Subtype and CD2 Aberrant Expression In B Cell Precursor ALL von Slamova, Lucie, Starkova, Julia, Fiser, Karel, Fronkova, Eva, Reznickova, Leona Rezkova, Zaliova, Marketa Kubricanova, Polgarova, Kamila, Stary, Jan, Trka, Jan, Hrusak, Ondrej, Mejstrikova, Ester

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Epigenetic Changes in CEBPα Gene and Xenotransplantation Model of B Cell Precursor Acute Lymphoblastic Leukemia Switching to Monocytoid Lineage During the Early Phase of the Treatm... von Slamova, Lucie, Starkova, Julia, Bornhauser, Beat C, Fronkova, Eva, Zaliova, Marketa Kubricanova, Reznickova, Leona, Volejnikova, Jana, Vodickova, Elena, Van Delft, Frederik W, Zemanova, Zuzana, Cario, Gunnar, Kalina, Tomas, Fiser, Karel, Figueroa, Maria E., Dworzak, Michael, Zuna, Jan, Trka, Jan, Stary, Jan, Hrusak, Ondrej, Bourquin, Jean-Pierre, Mejstrikova, Ester

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