HSPA5 is an essential host factor for Ebola virus infection von Patrick Reid, St, Shurtleff, Amy C., Costantino, Julie A., Tritsch, Sarah R., Retterer, Cary, Spurgers, Kevin B., Bavari, Sina

Volltext

Transcriptional Regulation of bcl-2 Mediated by the Sonic Hedgehog Signaling Pathway through gli-1 von Bigelow, Rebecca L.H., Chari, Nikhil S., Undén, Anne Birgitte, Spurgers, Kevin B., Lee, Sangjun, Roop, Dennis R., Toftgård, Rune, McDonnell, Timothy J.

Volltext

Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression von Spurgers, Kevin B., Gold, David L., Coombes, Kevin R., Bohnenstiehl, Nicole L., Mullins, Brian, Meyn, Raymond E., Logothetis, Christopher J., McDonnell, Timothy J.

Volltext

Oligonucleotide antiviral therapeutics: Antisense and RNA interference for highly pathogenic RNA viruses von Spurgers, Kevin B., Sharkey, C. Matthew, Warfield, Kelly L., Bavari, Sina

Volltext

Identification of Essential Filovirion-associated Host Factors by Serial Proteomic Analysis and RNAi Screen von Spurgers, Kevin B., Alefantis, Tim, Peyser, Brian D., Ruthel, Gordon T., Bergeron, Alison A., Costantino, Julie A., Enterlein, Sven, Kota, Krishna P., Boltz, R. C. Dutch, Aman, M. Javad, DelVecchio, Vito G., Bavari, Sina

Volltext

Second generation inactivated eastern equine encephalitis virus vaccine candidates protect mice against a lethal aerosol challenge von Honnold, Shelley P, Bakken, Russell R, Fisher, Diana, Lind, Cathleen M, Cohen, Jeffrey W, Eccleston, Lori T, Spurgers, Kevin B, Maheshwari, Radha K, Glass, Pamela J

Volltext

Burkholderia mallei tssM Encodes a Putative Deubiquitinase That Is Secreted and Expressed inside Infected RAW 264.7 Murine Macrophages von Shanks, John, Burtnick, Mary N, Brett, Paul J, Waag, David M, Spurgers, Kevin B, Ribot, Wilson J, Schell, Mark A, Panchal, Rekha G, Gherardini, Frank C, Wilkinson, Keith D, DeShazer, David

Volltext

Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B von Warfield, Kelly L., Schaaf, Kaitlyn R., DeWald, Lisa Evans, Spurgers, Kevin B., Wang, Wei, Stavale, Eric, Mendenhall, Michelle, Shilts, Meghan H., Stockwell, Timothy B., Barnard, Dale L., Ramstedt, Urban, Das, Suman R.

Volltext

1,5-Iodonaphthyl azide-inactivated V3526 protects against aerosol challenge with virulent venezuelan equine encephalitis virus von Gupta, Paridhi, Sharma, Anuj, Spurgers, Kevin B, Bakken, Russell R, Eccleston, Lori T, Cohen, Jeffrey W, Honnold, Shelley P, Glass, Pamela J, Maheshwari, Radha K

Volltext

Eastern equine encephalitis virus in mice II: pathogenesis is dependent on route of exposure von Honnold, Shelley P, Mossel, Eric C, Bakken, Russell R, Lind, Cathleen M, Cohen, Jeffrey W, Eccleston, Lori T, Spurgers, Kevin B, Erwin-Cohen, Rebecca, Glass, Pamela J, Maheshwari, Radha K

Volltext

Eastern equine encephalitis virus in mice I: clinical course and outcome are dependent on route of exposure von Honnold, Shelley P, Mossel, Eric C, Bakken, Russell R, Fisher, Diana, Lind, Cathleen M, Cohen, Jeffrey W, Eccleston, Lori T, Spurgers, Kevin B, Erwin-Cohen, Rebecca, Bradfute, Steven B, Maheshwari, Radha K, Glass, Pamela J

Volltext

Validation of a cell-based ELISA as a screening tool identifying anti-alphavirus small-molecule inhibitors von Spurgers, Kevin B., Hurt, Clarence R., Cohen, Jeffrey W., Eccelston, Lori T., Lind, Cathleen M., Lingappa, Vishwanath R., Glass, Pamela J.

Volltext

Development of High-Content Imaging Assays for Lethal Viral Pathogens von Panchal, Rekha G., Kota, Krishna P., Spurgers, Kevin B., Ruthel, Gordon, Tran, Julie P., Boltz, Robert C. “Dutch”, Bavari, Sina

Volltext

PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells von Kadowaki, Yoshihiko, Chari, Nikhil S., Teo, Albert E. K., Hashi, Akihiko, Spurgers, Kevin B., McDonnell, Timothy J.

Volltext

GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells von Honda, Tsuyoshi, Coppola, Simona, Ghibelli, Lina, Cho, Song H, Kagawa, Shunsuke, Spurgers, Kevin B, Brisbay, Shawn M, Roth, Jack A, Meyn, Raymond E, Fang, Bingliang, McDonnell, Timothy J

Volltext

Toward RNA interference-based therapy for filovirus infections von Spurgers, Kevin B., Silvestri, Lynn S., Warfield, Kelly L., Bavari, Sina

Volltext

A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells von Spurgers, Kevin B, Coombes, Kevin R, Meyn, Raymond E, Gold, David L, Logothetis, Christopher J, Johnson, Terry J, McDonnell, Timothy J

Volltext

A Recombinant Adenovirus Expressing Wild-Type Bax Induces Apoptosis in Prostate Cancer Cells Independently of Their Bcl-2 Status and Androgen Sensitivity von Honda, Tsuyoshi, Kagawa, Shunsuke, Spurgers, Kevin B., Gjertsen, Bjorn T., Roth, Jack A., Fang, Bingliang, Lowe, Stephanie L., Norris, James S., Meyn, Raymond E., McDonnell, Timothy J.

Volltext

NF- Kappa B1 (p50) Homodimers Contribute to Transcription of the bcl-2 Oncogene von Kurland, J F, Kodym, R, Story, MD, Spurgers, K B, McDonnell, T J, Meyn, R E

Volltext

Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of bcl-2 von GOMEZ-MANZANO, Candelaria, MITLIANGA, Paraskevi, YUNG, W. K, FUEYO, Juan, LEE, Ho-Young, HU, Min, SPURGERS, Kevin B, GLASS, Tricia L, KOUL, Dimpy, LIU, Ta-Jen, MCDONNELL, Timothy J

Volltext