Actin: a novel interaction partner of WT1 influencing its cell dynamic properties von Dudnakova, T, Spraggon, L, Slight, J, Hastie, N

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hnRNP-U directly interacts with WT1 and modulates WT1 transcriptional activation von SPRAGGON, L, DUDNAKOVA, T, SLIGHT, J, LUSTIG-YARIV, O, COTTERELL, J, HASTIE, N, MILES, C

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Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation von Davies, Jamie A., Ladomery, Michael, Hohenstein, Peter, Michael, Lydia, Shafe, Anna, Spraggon, Lee, Hastie, Nick

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The DNA sequence and analysis of human chromosome 6 von Mungall, A. J, Beck, S, Palmer, S. A, Edwards, C. A, Jones, M. C, Horton, R, Scott, C. E, Clamp, M. E, Milne, S, Almeida, J. P, Babbage, A. K, Bagguley, C. L, Bailey, J, Banerjee, R, Barker, D. J, Barlow, K. F, Beasley, H, Beasley, O, Bird, C. P, Blakey, S, Bray-Allen, S, Brown, A. J, Brown, J. Y, Burton, J, Chapman, J. C, Clark, S. Y, Clark, G, Clee, C. M, Clegg, S, Collier, R. E, Collins, J. E, Corby, N. R, Coville, G. J, Earthrowl, M. E, Ellington, A. E, Evans, K. A, Francis, M. D, Garner, P, Garnett, J, Gillson, C. J, Grafham, D. V, Grant, M, Gribble, S, Griffiths, C, Hall, R, Halls, K. S, Heathcott, R, Howden, P. J, Howell, G. R, Huckle, E, Humphray, S. J, Humphries, M. D, Hunt, A. R, Johnson, C. M, Joy, A. A, Kay, M, Kimberley, A. M, Laird, G. K, Lawlor, S, Leongamornlert, D. A, Lloyd, C. R, Lovell, J, Mashreghi-Mohammadi, M, Maslen, G. L, McCann, O. T, McLaren, S. J, McLay, K, McMurray, A, Novik, K. L, Overton-Larty, E. K, Parker, A, Patel, R, Phillimore, B, Phillips, S, Plumb, R. W, Ranby, S. A, Rice, C. M, Sheridan, E, Skuce, C. D, Smith, S, Spraggon, L, Squares, S. L, Tamlyn-Hall, G, Tester, J, Thorpe, A, Tromans, A, Wallis, J. M, West, A. P, White, S. S, Whitehead, S. L, Whittaker, H, Wild, A, Wilmer, T. E, Wood, J. M, Wray, P. W, Younger, R. M, Coulson, A, Hubbard, T, Sulston, J. E, Rogers, J

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Murine Denys–Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis von Patek, Charles E., Fleming, Stewart, Miles, Colin G., Bellamy, Christopher O., Ladomery, Michael, Spraggon, Lee, Mullins, John, Hastie, Nicholas D., Hooper, Martin L.

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hnRNP-U directly interacts with WT1 and modulates WT1 transcriptional activation von Spraggon, L, Dudnakova, T, Slight, J, Lustig-Yariv, O, Cotterell, J, Hastie, N, Miles, C

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Mice Lacking the 68-Amino-Acid, Mammal-Specific N-Terminal Extension of WT1 Develop Normally and Are Fertile von Miles, Colin G., Slight, Joan, Spraggon, Lee, O'Sullivan, Maureen, Patek, Charles, Hastie, Nicholas D.

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Genetic interactions between the Wilms' Tumor 1 gene and the p53 gene von MENKE, Aswin L, CLARKE, Alan R, LEITCH, Andrea, IJPENBERG, Annemieke, WILLIAMSON, Kathy A, SPRAGGON, Lee, HARRISON, David J, HASTIE, Nicholas D

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Motivating non-ratepaying households with feedback and social nudges: A cautionary tale von Crago, Christine L., Spraggon, John M., Hunter, Elizabeth

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Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain von Lee, Christian C, Jia, Yong, Li, Nanxin, Sun, Xiuying, Ng, Kenneth, Ambing, Eileen, Gao, Mu-Yun, Hua, Su, Chen, Connie, Kim, Sungjoon, Michellys, Pierre-Yves, Lesley, Scott A, Harris, Jennifer L, Spraggon, Glen

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A Wt1-Controlled Chromatin Switching Mechanism Underpins Tissue-Specific Wnt4 Activation and Repression von Essafi, Abdelkader, Webb, Anna, Berry, Rachel L., Slight, Joan, Burn, Sally F., Spraggon, Lee, Velecela, Victor, Martinez-Estrada, Ofelia M., Wiltshire, John H., Roberts, Stefan G.E., Brownstein, David, Davies, Jamie A., Hastie, Nicholas D., Hohenstein, Peter

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Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness von Khare, Shilpi, Nagle, Advait S., Biggart, Agnes, Lai, Yin H., Liang, Fang, Davis, Lauren C., Barnes, S. Whitney, Mathison, Casey J. N., Myburgh, Elmarie, Gao, Mu-Yun, Gillespie, J. Robert, Liu, Xianzhong, Tan, Jocelyn L., Stinson, Monique, Rivera, Ianne C., Ballard, Jaime, Yeh, Vince, Groessl, Todd, Federe, Glenn, Koh, Hazel X. Y., Venable, John D., Bursulaya, Badry, Shapiro, Michael, Mishra, Pranab K., Spraggon, Glen, Brock, Ansgar, Mottram, Jeremy C., Buckner, Frederick S., Rao, Srinivasa P. S., Wen, Ben G., Walker, John R., Tuntland, Tove, Molteni, Valentina, Glynne, Richard J., Supek, Frantisek

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self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain von Hampton, Eric N, Knuth, Mark W, Li, Jun, Harris, Jennifer L, Lesley, Scott A, Spraggon, Glen

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Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity von Li, Jun, Tumanut, Christine, Gavigan, Julie-Ann, Huang, Waan-Jeng, Hampton, Eric N, Tumanut, Rachelle, Suen, Ka Fai, Trauger, John W, Spraggon, Glen, Lesley, Scott A, Liau, Gene, Yowe, David, Harris, Jennifer L

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FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections von Nesta, Barbara, Spraggon, Glen, Alteri, Christopher, Moriel, Danilo Gomes, Rosini, Roberto, Veggi, Daniele, Smith, Sara, Bertoldi, Isabella, Pastorello, Ilaria, Ferlenghi, Ilaria, Fontana, Maria Rita, Frankel, Gad, Mobley, Harry L T, Rappuoli, Rino, Pizza, Mariagrazia, Serino, Laura, Soriani, Marco

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Structural Genomics of the Thermotoga maritima Proteome Implemented in a High-Throughput Structure Determination Pipeline von Lesley, Scott A., Kuhn, Peter, Godzik, Adam, Deacon, Ashley M., Mathews, Irimpan, Kreusch, Andreas, Spraggon, Glen, Klock, Heath E., McMullan, Daniel, Shin, Tanya, Vincent, Juli, Robb, Alyssa, Brinen, Linda S., Miller, Mitchell D., McPhillips, Timothy M., Miller, Mark A., Scheibe, Daniel, Canaves, Jaume M., Guda, Chittibabu, Jaroszewski, Lukasz, Selby, Thomas L., Elsliger, Marc-Andre, Wooley, John, Taylor, Susan S., Hodgson, Keith O., Wilson, Ian A., Schultz, Peter G., Stevens, Raymond C.

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The site-specific incorporation of p -iodo- L -phenylalanine into proteins for structure determination von Spraggon, Glen, Schultz, Peter G, Xie, Jianming, Wang, Lei, Wu, Ning, Brock, Ansgar

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Thin and lumpy: An experimental investigation of water quality trading von Suter, Jordan F., Spraggon, John M., Poe, Gregory L.

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Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations von Spraggon, Glen, Hornsby, Michael, Shipway, Aaron, Tully, David C., Bursulaya, Badry, Danahay, Henry, Harris, Jennifer L., Lesley, Scott A.

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An approach to rapid protein crystallization using nanodroplets von Santarsiero, B. D., Yegian, D. T., Lee, C. C., Spraggon, G., Gu, J., Scheibe, D., Uber, D. C., Cornell, E. W., Nordmeyer, R. A., Kolbe, W. F., Jin, J., Jones, A. L., Jaklevic, J. M., Schultz, P. G., Stevens, R. C.

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