Targeting Resistance in Egfr-Mutant Non-Small Cell Lung Cancer (Nsclc): Preclinical Evidence Supporting the Combination of Egfr Tyrosine Kinase Inhibitors (Tkis) Azd9291 and Gefiti... von Cross, D., D'Cruz, C., Eberlein, C., Spitzler, P., Ichihara, E., Meador, C., Ashton, S., Mellor, M., Stewart, R., Smith, P., Schuller, A., Frigault, M., Pao, W., Jewsbury, P.J.

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466PTARGETING RESISTANCE IN EGFR-MUTANT NON-SMALL CELL LUNG CANCER (NSCLC): PRECLINICAL EVIDENCE SUPPORTING THE COMBINATION OF EGFR TYROSINE KINASE INHIBITORS (TKIS) AZD9291 AND GE... von Cross, D., D'Cruz, C., Eberlein, C., Spitzler, P., Ichihara, E., Meador, C., Ashton, S., Mellor, M., Stewart, R., Smith, P., Schuller, A., Frigault, M., Pao, W., Jewsbury, P.J.

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Pre-Clinical and Clinical Evaluation of Azd9291, a Mutation-Specific Inhibitor, in Treatment-Naïve Egfr Mutated Nsclc von Ramalingam, S.S., Ohe, Y., Nogami, N., Yang, J.C., Eberlein, C., Ashton, S., Mellor, M., Spitzler, P., Meador, C., Ichihara, E., Cross, D., Pao, W., Ballard, P., Hughes, G., Cantarini, M., Frewer, P., Ghiorghiu, S., Janne, P.A.

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454PPRE-CLINICAL AND CLINICAL EVALUATION OF AZD9291, A MUTATION-SPECIFIC INHIBITOR, IN TREATMENT-NAïVE EGFR MUTATED NSCLC von Ramalingam, S.S., Ohe, Y., Nogami, N., Yang, J.C., Eberlein, C., Ashton, S., Mellor, M., Spitzler, P., Meador, C., Ichihara, E., Cross, D., Pao, W., Ballard, P., Hughes, G., Cantarini, M., Frewer, P., Ghiorghiu, S., Janne, P.A.

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AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer von Cross, Darren A E, Ashton, Susan E, Ghiorghiu, Serban, Eberlein, Cath, Nebhan, Caroline A, Spitzler, Paula J, Orme, Jonathon P, Finlay, M Raymond V, Ward, Richard A, Mellor, Martine J, Hughes, Gareth, Rahi, Amar, Jacobs, Vivien N, Red Brewer, Monica, Ichihara, Eiki, Sun, Jing, Jin, Hailing, Ballard, Peter, Al-Kadhimi, Katherine, Rowlinson, Rachel, Klinowska, Teresa, Richmond, Graham H P, Cantarini, Mireille, Kim, Dong-Wan, Ranson, Malcolm R, Pao, William

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