Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals von Levine, Michelle S., Bakker, Bjorn, Boeckx, Bram, Moyett, Julia, Lu, James, Vitre, Benjamin, Spierings, Diana C., Lansdorp, Peter M., Cleveland, Don W., Lambrechts, Diether, Foijer, Floris, Holland, Andrew J.

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Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses von Shaikh, Nadeem, Mazzagatti, Alice, De Angelis, Simone, Johnson, Sarah C, Bakker, Bjorn, Spierings, Diana C J, Wardenaar, René, Maniati, Eleni, Wang, Jun, Boemo, Michael A, Foijer, Floris, McClelland, Sarah E

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A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity von Nelson, Louisa, Tighe, Anthony, Golder, Anya, Littler, Samantha, Bakker, Bjorn, Moralli, Daniela, Murtuza Baker, Syed, Donaldson, Ian J., Spierings, Diana C. J., Wardenaar, René, Neale, Bethanie, Burghel, George J., Winter-Roach, Brett, Edmondson, Richard, Clamp, Andrew R., Jayson, Gordon C., Desai, Sudha, Green, Catherine M., Hayes, Andy, Foijer, Floris, Morgan, Robert D., Taylor, Stephen S.

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Single-cell template strand sequencing by Strand-seq enables the characterization of individual homologs von Sanders, Ashley D, Falconer, Ester, Hills, Mark, Spierings, Diana C J, Lansdorp, Peter M

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Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing von Montizaan, Daphne, Bartucci, Roberta, Reker-Smit, Catharina, de Weerd, Sander, Åberg, Christoffer, Guryev, Victor, Spierings, Diana C. J., Salvati, Anna

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Author Correction: Genome-wide forward genetic screening to identify receptors and proteins mediating nanoparticle uptake and intracellular processing von Montizaan, Daphne, Bartucci, Roberta, Reker-Smit, Catharina, de Weerd, Sander, Åberg, Christoffer, Guryev, Victor, Spierings, Diana C. J., Salvati, Anna

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Short-term molecular consequences of chromosome mis-segregation for genome stability von Garribba, Lorenza, De Feudis, Giuseppina, Martis, Valentino, Galli, Martina, Dumont, Marie, Eliezer, Yonatan, Wardenaar, René, Ippolito, Marica Rosaria, Iyer, Divya Ramalingam, Tijhuis, Andréa E., Spierings, Diana C. J., Schubert, Michael, Taglietti, Silvia, Soriani, Chiara, Gemble, Simon, Basto, Renata, Rhind, Nick, Foijer, Floris, Ben-David, Uri, Fachinetti, Daniele, Doksani, Ylli, Santaguida, Stefano

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Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies von Bakker, Bjorn, Taudt, Aaron, Belderbos, Mirjam E, Porubsky, David, Spierings, Diana C J, de Jong, Tristan V, Halsema, Nancy, Kazemier, Hinke G, Hoekstra-Wakker, Karina, Bradley, Allan, de Bont, Eveline S J M, van den Berg, Anke, Guryev, Victor, Lansdorp, Peter M, Colomé-Tatché, Maria, Foijer, Floris

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A non-genetic switch triggers alternative telomere lengthening and cellular immortalization in ATRX deficient cells von Turkalo, Timothy K., Maffia, Antonio, Schabort, Johannes J., Regalado, Samuel G., Bhakta, Mital, Blanchette, Marco, Spierings, Diana C. J., Lansdorp, Peter M., Hockemeyer, Dirk

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Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer c... von Schoonen, Pepijn M., Kok, Yannick P., Wierenga, Elles, Bakker, Bjorn, Foijer, Floris, Spierings, Diana C. J., Vugt, Marcel A. T. M.

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The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability von Hintzen, Dorine C, Soto, Mar, Schubert, Michael, Bakker, Bjorn, Spierings, Diana C. J, Szuhai, Karoly, Lansdorp, Peter M, Kluin, Roel J. C, Foijer, Floris, Medema, René H, Raaijmakers, Jonne A

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Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51 von Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni Maria, de Kanter, Jurrian K., Kok, Yannick P., Everts, Marieke, de Boer, H. Rudolf, Audrey, Anastasia, Bakker, Femke J., Wierenga, Elles, Tijsterman, Marcel, Guryev, Victor, Spierings, Diana C. J., Knipscheer, Puck, van Boxtel, Ruben, Ray Chaudhuri, Arnab, Lansdorp, Peter M., van Vugt, Marcel A. T. M.

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Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia von Woodward, Eleanor L., Yang, Minjun, Moura-Castro, Larissa H., van den Bos, Hilda, Gunnarsson, Rebeqa, Olsson-Arvidsson, Linda, Spierings, Diana C. J., Castor, Anders, Duployez, Nicolas, Zaliova, Marketa, Zuna, Jan, Johansson, Bertil, Foijer, Floris, Paulsson, Kajsa

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TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells von van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.

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Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids von Bolhaqueiro, Ana C. F., Ponsioen, Bas, Bakker, Bjorn, Klaasen, Sjoerd J., Kucukkose, Emre, van Jaarsveld, Richard H., Vivié, Judith, Verlaan-Klink, Ingrid, Hami, Nizar, Spierings, Diana C. J., Sasaki, Nobuo, Dutta, Devanjali, Boj, Sylvia F., Vries, Robert G. J., Lansdorp, Peter M., van de Wetering, Marc, van Oudenaarden, Alexander, Clevers, Hans, Kranenburg, Onno, Foijer, Floris, Snippert, Hugo J. G., Kops, Geert J. P. L.

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Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons von van den Bos, Hilda, Spierings, Diana C J, Taudt, Aaron S, Bakker, Bjorn, Porubský, David, Falconer, Ester, Novoa, Carolina, Halsema, Nancy, Kazemier, Hinke G, Hoekstra-Wakker, Karina, Guryev, Victor, den Dunnen, Wilfred F A, Foijer, Floris, Tatché, Maria Colomé, Boddeke, Hendrikus W G M, Lansdorp, Peter M

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InvertypeR: Bayesian inversion genotyping with Strand-seq data von Hanlon, Vincent C. T., Mattsson, Carl-Adam, Spierings, Diana C. J., Guryev, Victor, Lansdorp, Peter M.

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BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes von van Wietmarschen, Niek, Merzouk, Sarra, Halsema, Nancy, Spierings, Diana C. J., Guryev, Victor, Lansdorp, Peter M.

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Improved assembly and variant detection of a haploid human genome using single‐molecule, high‐fidelity long reads von Vollger, Mitchell R., Logsdon, Glennis A., Audano, Peter A., Sulovari, Arvis, Porubsky, David, Peluso, Paul, Wenger, Aaron M., Concepcion, Gregory T., Kronenberg, Zev N., Munson, Katherine M., Baker, Carl, Sanders, Ashley D., Spierings, Diana C.J., Lansdorp, Peter M., Surti, Urvashi, Hunkapiller, Michael W., Eichler, Evan E.

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Replication catastrophe is responsible for intrinsic PAR glycohydrolase inhibitor-sensitivity in patient-derived ovarian cancer models von Coulson-Gilmer, Camilla, Morgan, Robert D., Nelson, Louisa, Barnes, Bethany M., Tighe, Anthony, Wardenaar, Rene, Spierings, Diana C. J., Schlecht, Helene, Burghel, George J., Foijer, Floris, Desai, Sudha, McGrail, Joanne C., Taylor, Stephen S.

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