A combined radio-immunotherapy regimen eradicates late-stage tumors in mice von Rakhmilevich, Alexander L, Tsarovsky, Noah W, Felder, Mildred, Zaborek, Jen, Moram, Sritha, Erbe, Amy K, Pieper, Alexander A, Spiegelman, Dan V, Cheng, Emily M, Witt, Cole M, Overwijk, Willem W, Morris, Zachary S, Sondel, Paul M

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Factors impacting the efficacy of the in-situ vaccine with CpG and OX40 agonist von Pieper, Alexander A., Spiegelman, Dan V., Felder, Mildred A. R., Feils, Arika S., Tsarovsky, Noah W., Zaborek, Jen, Morris, Zachary S., Erbe, Amy K., Rakhmilevich, Alexander L., Sondel, Paul M.

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Generation of Novel Immunocompetent Mouse Cell Lines to Model Experimental Metastasis of High-Risk Neuroblastoma von Dhamdhere, Mayura R, Spiegelman, Dan V, Schneper, Lisa, Erbe, Amy K, Sondel, Paul M, Spiegelman, Vladimir S

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Abstract 2389: In vivo multiphoton autofluorescence imaging is sensitive to CD8 T cell and tumor cell metabolic changes during immunotherapy in a murine melanoma model von Heaton, Alexa R., Hoefges, Anna, Rehani, Peter R., Burkard, Nathaniel J., Feils, Arika S., Spiegelman, Dan V., Tsarovsky, Noah W., Hampton, Alina A., Gurel, Amy K. Erbe, Rakhmilevich, Alexander L., Sondel, Paul M., Skala, Melissa C.

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De novo mutations in moderate or severe intellectual disability von Hamdan, Fadi F, Srour, Myriam, Capo-Chichi, Jose-Mario, Daoud, Hussein, Nassif, Christina, Patry, Lysanne, Massicotte, Christine, Ambalavanan, Amirthagowri, Spiegelman, Dan, Diallo, Ousmane, Henrion, Edouard, Dionne-Laporte, Alexandre, Fougerat, Anne, Pshezhetsky, Alexey V, Venkateswaran, Sunita, Rouleau, Guy A, Michaud, Jacques L

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Errα and Gabpa/b Specify PGC-1α-Dependent Oxidative Phosphorylation Gene Expression That Is Altered in Diabetic Muscle von Mootha, Vamsi K., Handschin, Christoph, Arlow, Dan, Xie, Xiaohui, St. Pierre, Julie, Sihag, Smita, Yang, Wenli, Altshuler, David, Puigserver, Pere, Patterson, Nick, Willy, Patricia J., Schulman, Ira G., Heyman, Richard A., Lander, Eric S., Spiegelman, Bruce M.

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Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia von Gan-Or, Ziv, Bouslam, Naima, Birouk, Nazha, Lissouba, Alexandra, Chambers, Daniel B., Vérièpe, Julie, Androschuk, Alaura, Laurent, Sandra B., Rochefort, Daniel, Spiegelman, Dan, Dionne-Laporte, Alexandre, Szuto, Anna, Liao, Meijiang, Figlewicz, Denise A., Bouhouche, Ahmed, Benomar, Ali, Yahyaoui, Mohamed, Ouazzani, Reda, Yoon, Grace, Dupré, Nicolas, Suchowersky, Oksana, Bolduc, Francois V., Parker, J. Alex, Dion, Patrick A., Drapeau, Pierre, Rouleau, Guy A., Ouled Amar Bencheikh, Bouchra

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De novo variants in sporadic cases of childhood onset schizophrenia von Ambalavanan, Amirthagowri, Girard, Simon L, Ahn, Kwangmi, Zhou, Sirui, Dionne-Laporte, Alexandre, Spiegelman, Dan, Bourassa, Cynthia V, Gauthier, Julie, Hamdan, Fadi F, Xiong, Lan, Dion, Patrick A, Joober, Ridha, Rapoport, Judith, Rouleau, Guy A

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High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies von Myers, Candace T., Cossette, Patrick, Lemay, Philippe, Spiegelman, Dan, Laporte, Alexandre Dionne, Nassif, Christina, Diallo, Ousmane, Monlong, Jean, Cadieux-Dion, Maxime, Dobrzeniecka, Sylvia, Meloche, Caroline, Retterer, Kyle, Cho, Megan T., Rosenfeld, Jill A., Bi, Weimin, Massicotte, Christine, Miguet, Marguerite, Brunga, Ledia, Regan, Brigid M., Mo, Kelly, Tam, Cory, Hollingsworth, Georgie, FitzPatrick, David R., Canham, Natalie, Blair, Edward, Kerr, Bronwyn, Fry, Andrew E., Thomas, Rhys H., Shelagh, Joss, Hurst, Jane A., Brittain, Helen, Blyth, Moira, Lebel, Robert Roger, Gerkes, Erica H., Davis-Keppen, Laura, Stein, Quinn, Dorison, Sara J., Benke, Paul J., Fassi, Emily, Corsten-Janssen, Nicole, Kamsteeg, Erik-Jan, Mau-Them, Frederic T., Bruel, Ange-Line, Verloes, Alain, Õunap, Katrin, Wojcik, Monica H., Albert, Dara V.F., Venkateswaran, Sunita, Ware, Tyson, Liu, Yu-Chi, Mohammad, Shekeeb S., Bizargity, Peyman, Bacino, Carlos A., Leuzzi, Vincenzo, Martinelli, Simone, Dallapiccola, Bruno, Tartaglia, Marco, Blumkin, Lubov, Wierenga, Klaas J., Purcarin, Gabriela, O’Byrne, James J., Stockler, Sylvia, Lehman, Anna, Keren, Boris, Nougues, Marie-Christine, Mignot, Cyril, Auvin, Stéphane, Nava, Caroline, Hiatt, Susan M., Bebin, Martina, Shao, Yunru, Scaglia, Fernando, Frye, Richard E., Jarjour, Imad T., Jacques, Stéphanie, Boucher, Renee-Myriam, Riou, Emilie, Srour, Myriam, Carmant, Lionel, Lortie, Anne, Major, Philippe, Diadori, Paola, Dubeau, François, D’Anjou, Guy, Bourque, Guillaume, Berkovic, Samuel F., Sadleir, Lynette G., Campeau, Philippe M., Kibar, Zoha, Lafrenière, Ronald G., Girard, Simon L., Mercimek-Mahmutoglu, Saadet, Boelman, Cyrus, Rouleau, Guy A., Scheffer, Ingrid E., Mefford, Heather C., Andrade, Danielle M., Rossignol, Elsa, Minassian, Berge A., Michaud, Jacques L.

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Exome Sequencing Identifies FUS Mutations as a Cause of Essential Tremor von Merner, Nancy D., Girard, Simon L., Catoire, Hélène, Bourassa, Cynthia V., Belzil, Véronique V., Rivière, Jean-Baptiste, Hince, Pascale, Levert, Annie, Dionne-Laporte, Alexandre, Spiegelman, Dan, Noreau, Anne, Diab, Sabrina, Szuto, Anna, Fournier, Hélène, Raelson, John, Belouchi, Majid, Panisset, Michel, Cossette, Patrick, Dupré, Nicolas, Bernard, Geneviève, Chouinard, Sylvain, Dion, Patrick A., Rouleau, Guy A.

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Evolution of a Human-Specific Tandem Repeat Associated with ALS von Course, Meredith M., Gudsnuk, Kathryn, Smukowski, Samuel N., Winston, Kosuke, Desai, Nitin, Ross, Jay P., Sulovari, Arvis, Bourassa, Cynthia V., Spiegelman, Dan, Couthouis, Julien, Yu, Chang-En, Tsuang, Debby W., Jayadev, Suman, Kay, Mark A., Gitler, Aaron D., Dupre, Nicolas, Eichler, Evan E., Dion, Patrick A., Rouleau, Guy A., Valdmanis, Paul N.

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Genetic architecture and adaptations of Nunavik Inuit von Zhou, Sirui, Xie (谢萍星), Pingxing, Quoibion, Amélie, Ambalavanan, Amirthagowri, Dionne-Laporte, Alexandre, Spiegelman, Dan, Bourassa, Cynthia V., Xiong, Lan, Dion, Patrick A., Rouleau, Guy A.

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RNF213 Is Associated with Intracranial Aneurysms in the French-Canadian Population von Zhou, Sirui, Ambalavanan, Amirthagowri, Rochefort, Daniel, Xie, Pingxing, Bourassa, Cynthia V., Hince, Pascale, Dionne-Laporte, Alexandre, Spiegelman, Dan, Gan-Or, Ziv, Mirarchi, Cathy, Zaharieva, Vessela, Dupré, Nicolas, Kobayashi, Hatasu, Hitomi, Toshiaki, Harada, Kouji, Koizumi, Akio, Xiong, Lan, Dion, Patrick A., Rouleau, Guy A.

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Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population von Zhou, Sirui, Xiong, Lan, Xie, Pingxing, Ambalavanan, Amirthagowri, Bourassa, Cynthia V, Dionne-Laporte, Alexandre, Spiegelman, Dan, Turcotte Gauthier, Maude, Henrion, Edouard, Diallo, Ousmane, Dion, Patrick A, Rouleau, Guy A

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Exome sequencing of sporadic childhood‐onset schizophrenia suggests the contribution of X‐linked genes in males von Ambalavanan, Amirthagowri, Chaumette, Boris, Zhou, Sirui, Xie, Pingxing, He, Qin, Spiegelman, Dan, Dionne‐Laporte, Alexandre, Bourassa, Cynthia V., Therrien, Martine, Rochefort, Daniel, Xiong, Lan, Dion, Patrick A., Joober, Ridha, Rapoport, Judith L., Girard, Simon L., Rouleau, Guy A.

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Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder von Li, Jiao, Ruskey, Jennifer A., Arnulf, Isabelle, Dauvilliers, Yves, Hu, Michele T.M., Högl, Birgit, Leblond, Claire S., Zhou, Sirui, Ambalavanan, Amirthagowri, Ross, Jay P., Bourassa, Cynthia V., Spiegelman, Dan, Laurent, Sandra B, Stefani, Ambra, Charley Monaca, Christelle, Cochen De Cock, Valérie, Boivin, Michel, Ferini‐Strambi, Luigi, Plazzi, Giuseppe, Antelmi, Elena, Young, Peter, Heidbreder, Anna, Labbe, Catherine, Ferman, Tanis J., Dion, Patrick A., Fan, Dongsheng, Desautels, Alex, Gagnon, Jean‐François, Dupré, Nicolas, Fon, Edward A., Montplaisir, Jacques Y., Boeve, Bradley F., Postuma, Ronald B., Rouleau, Guy A., Ross, Owen A., Gan‐Or, Ziv

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Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population von Zhou, Sirui, Gan-Or, Ziv, Ambalavanan, Amirthagowri, Lai, Dongbing, Xie, Pingxing, Bourassa, Cynthia V., Strong, Stephanie, Ross, Jay P., Dionne-Laporte, Alexandre, Spiegelman, Dan, Dupré, Nicolas, Foroud, Tatiana M, Xiong, Lan, Dion, Patrick A., Rouleau, Guy A.

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Absence of Mutation Enrichment for Genes Phylogenetically Conserved in the Olivocerebellar Motor Circuitry in a Cohort of Canadian Essential Tremor Cases von Schmouth, Jean-François, Houle, Gabrielle, Ambalavanan, Amirthagowri, Leblond, Claire S., Spiegelman, Dan, Laurent, Sandra B., Bourassa, Cynthia V., Panisset, Michel, Chouinard, Sylvain, Dupré, Nicolas, Vilariño-Güell, Carles, Rajput, Alex, Dion, Patrick A., Rouleau, Guy A.

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Teneurin transmembrane protein 4 is not a cause for essential tremor in a Canadian population von Houle, Gabrielle, Schmouth, Jean‐François, Leblond, Claire S., Ambalavanan, Amirthagowri, Spiegelman, Dan, Laurent, Sandra B., Bourassa, Cynthia V., Panisset, Michel, Chouinard, Sylvain, Dupré, Nicolas, Vilariño‐Güell, Carles, Rajput, Alex, Dion, Patrick A., Rouleau, Guy A.

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Teneurin transmembrane protein 4 is not a cause for essential tremor in a Canadian population: TENM4 and Essential Tremor von Houle, Gabrielle, Schmouth, Jean-François, Leblond, Claire S., Ambalavanan, Amirthagowri, Spiegelman, Dan, Laurent, Sandra B., Bourassa, Cynthia V., Panisset, Michel, Chouinard, Sylvain, Dupré, Nicolas, Vilariño-Güell, Carles, Rajput, Alex, Dion, Patrick A., Rouleau, Guy A.

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