Microsatellite instability status determined by next‐generation sequencing and compared with PD‐L1 and tumor mutational burden in 11,348 patients von Vanderwalde, Ari, Spetzler, David, Xiao, Nianqing, Gatalica, Zoran, Marshall, John

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Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy von Hodges, Tiffany R, Ott, Martina, Xiu, Joanne, Gatalica, Zoran, Swensen, Jeff, Zhou, Shouhao, Huse, Jason T, de Groot, John, Li, Shulin, Overwijk, Willem W, Spetzler, David, Heimberger, Amy B

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Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer von Abraham, Jim P., Magee, Daniel, Cremolini, Chiara, Antoniotti, Carlotta, Halbert, David D., Xiu, Joanne, Stafford, Phillip, Berry, Donald A., Oberley, Matthew J., Shields, Anthony F., Marshall, John L., Salem, Mohamed E., Falcone, Alfredo, Grothey, Axel, Hall, Michael J., Venook, Alan P., Lenz, Heinz-Josef, Helmstetter, Anthony, Korn, W. Michael, Spetzler, David B.

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Immune evasion in HPV⁻ head and neck precancer–cancer transition is driven by an aneuploid switch involving chromosome 9p loss von William, William N., Zhao, Xin, Bianchi, Joy J., Lin, Heather Y., Cheng, Pan, Lee, J. Jack, Carter, Hannah, Alexandrov, Ludmil B., Abraham, Jim P., Spetzler, David B., Dubinett, Steven M., Cleveland, Don W., Cavenee, Webster, Davoli, Teresa, Lippman, Scott M.

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Elastic coupling power stroke mechanism of the F₁-ATPase molecular motor von Martin, James L., Ishmukhametov, Robert, Spetzler, David, Hornung, Tassilo, Frasch, Wayne D.

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Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications von Moretto, Roberto, Elliott, Andrew, Zhang, Jian, Arai, Hiroyuki, Germani, Marco Maria, Conca, Veronica, Xiu, Joanne, Stafford, Phillip, Oberley, Matthew, Abraham, Jim, Spetzler, David, Rossini, Daniele, Antoniotti, Carlotta, Marshall, John, Shields, Anthony, Lopes, Gilberto, Lonardi, Sara, Pietrantonio, Filippo, Tomasello, Gianluca, Passardi, Alessandro, Tamburini, Emiliano, Santini, Daniele, Aprile, Giuseppe, Masi, Gianluca, Falcone, Alfredo, Lenz, Heinz-Josef, Korn, Michael, Cremolini, Chiara

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Somatic 9p24.1 alterations in HPV - head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity von Zhao, Xin, Cohen, Ezra E W, William, Jr, William N, Bianchi, Joy J, Abraham, Jim P, Magee, Daniel, Spetzler, David B, Gutkind, J Silvio, Alexandrov, Ludmil B, Cavenee, Webster K, Lippman, Scott M, Davoli, Teresa

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Molecular Profiling of the Metaplastic Spindle Cell Carcinoma of the Breast Reveals Potentially Targetable Biomarkers von Vranic, Semir, Stafford, Phillip, Palazzo, Juan, Skenderi, Faruk, Swensen, Jeffrey, Xiu, Joanne, Spetzler, David, Gatalica, Zoran

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Direct observation of stepped proteolipid ring rotation in E. coli FoF1-ATP synthase von Ishmukhametov, Robert, Hornung, Tassilo, Spetzler, David, Frasch, Wayne D

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Pan-tumor survey of ROS1 fusions detected by next-generation RNA and whole transcriptome sequencing von Nagasaka, Misako, Zhang, Shannon S, Baca, Yasmine, Xiu, Joanne, Nieva, Jorge, Vanderwalde, Ari, Swensen, Jeffrey J, Spetzler, David, Korn, Wolfgang Michael, Raez, Luis E, Liu, Stephen V, Ou, Sai-Hong Ignatius

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Profiling plasma extracellular vesicle by pluronic block-copolymer based enrichment method unveils features associated with breast cancer aggression, metastasis and invasion von Zhong, Zhenyu, Rosenow, Matthew, Xiao, Nick, Spetzler, David

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Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict tumor type von Abraham, Jim, Heimberger, Amy B., Marshall, John, Heath, Elisabeth, Drabick, Joseph, Helmstetter, Anthony, Xiu, Joanne, Magee, Daniel, Stafford, Phillip, Nabhan, Chadi, Antani, Sourabh, Johnston, Curtis, Oberley, Matthew, Korn, Wolfgang Michael, Spetzler, David

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Response to “The need for validation of MI GPSai in patients with CUP: Comment on: “Machine learning analysis using 77,044 genomic and transcriptomic profiles to accurately predict... von Abraham, Jim, Nabhan, Chadi, Oberley, Matthew, Korn, Wolfgang Michael, Spetzler, David

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Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes von Domenyuk, Valeriy, Gatalica, Zoran, Santhanam, Radhika, Wei, Xixi, Stark, Adam, Kennedy, Patrick, Toussaint, Brandon, Levenberg, Symon, Wang, Jie, Xiao, Nianqing, Greil, Richard, Rinnerthaler, Gabriel, Gampenrieder, Simon P., Heimberger, Amy B., Berry, Donald A., Barker, Anna, Quackenbush, John, Marshall, John L., Poste, George, Vacirca, Jeffrey L., Vidal, Gregory A., Schwartzberg, Lee S., Halbert, David D., Voss, Andreas, Magee, Daniel, Miglarese, Mark R., Famulok, Michael, Mayer, Günter, Spetzler, David

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Pan-tumor survey of RET fusions as detected by next-generation RNA sequencing identified RET fusion positive colorectal carcinoma as a unique molecular subset von Nagasaka, Misako, Brazel, Danielle, Baca, Yasmine, Xiu, Joanne, Al-Hallak, Mohammed Najeeb, Kim, Chul, Nieva, Jorge, Swensen, Jeffrey J., Spetzler, David, Korn, Wolfgang Michael, Socinski, Mark A., Raez, Luis E., Halmos, Balazs, Ou, Sai-Hong Ignatius

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BRCA1/2 Reversion Mutations in Patients Treated with Poly ADP-Ribose Polymerase (PARP) Inhibitors or Platinum Agents von Darabi, Sourat, Braxton, David R, Xiu, Joanne, Carneiro, Benedito A, Swensen, Jeff, Antonarakis, Emmanuel S, Liu, Stephen V, McKay, Rana R, Spetzler, David, El-Deiry, Wafik S, Demeure, Michael J

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Microsecond Time Scale Rotation Measurements of Single F1-ATPase Molecules von Spetzler, David, York, Justin, Daniel, Douglas, Fromme, Raimund, Lowry, David, Frasch, Wayne

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Pan-cancer analysis of RNA expression of ANGIOTENSIN-I-CONVERTING ENZYME 2 reveals high variability and possible impact on COVID-19 clinical outcomes von Elliott, Andrew, Saul, Michelle, Zeng, Jia, Marshall, John L., Kim, Edward S., Nagasaka, Misako, Lenz, Heinz-Josef, Schwartzberg, Lee, Spetzler, David, Abraham, Jim, Xiu, Joanne, Stafford, Phillip, Michael Korn, W.

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Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies von Garber, Sarah T., Hashimoto, Yuuri, Weathers, Shiao-Pei, Xiu, Joanne, Gatalica, Zoran, Verhaak, Roel G. W., Zhou, Shouhao, Fuller, Gregory N., Khasraw, Mustafa, de Groot, John, Reddy, Sandeep K., Spetzler, David, Heimberger, Amy B.

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Multi-platform molecular profiling of a large cohort of glioblastomas reveals potential therapeutic strategies von Xiu, Joanne, Piccioni, David, Juarez, Tiffany, Pingle, Sandeep C, Hu, Jethro, Rudnick, Jeremy, Fink, Karen, Spetzler, David B, Maney, Todd, Ghazalpour, Anatole, Bender, Ryan, Gatalica, Zoran, Reddy, Sandeep, Sanai, Nader, Idbaih, Ahmed, Glantz, Michael, Kesari, Santosh

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