Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter von Schulte, Tim, Chaves-Sanjuan, Antonio, Mazzini, Giulia, Speranzini, Valentina, Lavatelli, Francesca, Ferri, Filippo, Palizzotto, Carlo, Mazza, Maria, Milani, Paolo, Nuvolone, Mario, Vogt, Anne-Cathrine, Vogel, Monique, Palladini, Giovanni, Merlini, Giampaolo, Bolognesi, Martino, Ferro, Silvia, Zini, Eric, Ricagno, Stefano

Volltext

Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation von Pilotto, Simona, Speranzini, Valentina, Tortorici, Marcello, Durand, Dominique, Fish, Alexander, Valente, Sergio, Forneris, Federico, Mai, Antonello, Sixma, Titia K., Vachette, Patrice, Mattevi, Andrea

Volltext

Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis von Schulte, Tim, Chaves-Sanjuan, Antonio, Speranzini, Valentina, Sicking, Kevin, Milazzo, Melissa, Mazzini, Giulia, Rognoni, Paola, Caminito, Serena, Milani, Paolo, Marabelli, Chiara, Corbelli, Alessandro, Diomede, Luisa, Fiordaliso, Fabio, Anastasia, Luigi, Pappone, Carlo, Merlini, Giampaolo, Bolognesi, Martino, Nuvolone, Mario, Fernández-Busnadiego, Rubén, Palladini, Giovanni, Ricagno, Stefano

Volltext

Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil von Omoto, Shinya, Speranzini, Valentina, Hashimoto, Takashi, Noshi, Takeshi, Yamaguchi, Hiroto, Kawai, Makoto, Kawaguchi, Keiko, Uehara, Takeki, Shishido, Takao, Naito, Akira, Cusack, Stephen

Volltext

LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors von Pilotto, Simona, Speranzini, Valentina, Marabelli, Chiara, Rusconi, Francesco, Toffolo, Emanuela, Grillo, Barbara, Battaglioli, Elena, Mattevi, Andrea

Volltext

Probing the interaction of the p53 C-terminal domain to the histone demethylase LSD1 von Speranzini, Valentina, Ciossani, Giuseppe, Marabelli, Chiara, Mattevi, Andrea

Volltext

Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation von Broggini, Luca, Barzago, Maria Monica, Speranzini, Valentina, Schulte, Tim, Sonzini, Federica, Giono, Matteo, Romeo, Margherita, Milani, Paolo, Caminito, Serena, Mazzini, Giulia, Rognoni, Paola, Merlini, Giampaolo, Pappone, Carlo, Anastasia, Luigi, Nuvolone, Mario, Palladini, Giovanni, Diomede, Luisa, Ricagno, Stefano

Volltext

Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106 von Kouba, Tomas, Dubankova, Anna, Drncova, Petra, Donati, Elisa, Vidossich, Pietro, Speranzini, Valentina, Pflug, Alex, Huchting, Johanna, Meier, Chris, De Vivo, Marco, Cusack, Stephen

Volltext

An N-glycosylation hotspot in immunoglobulin κ light chains is associated with AL amyloidosis von Nevone, Alice, Girelli, Maria, Mangiacavalli, Silvia, Paiva, Bruno, Milani, Paolo, Cascino, Pasquale, Piscitelli, Maggie, Speranzini, Valentina, Cartia, Claudio Salvatore, Benvenuti, Pietro, Goicoechea, Ibai, Fazio, Francesca, Basset, Marco, Foli, Andrea, Nanci, Martina, Mazzini, Giulia, Caminito, Serena, Sesta, Melania Antonietta, Casarini, Simona, Rognoni, Paola, Lavatelli, Francesca, Petrucci, Maria Teresa, Olimpieri, Pier Paolo, Ricagno, Stefano, Arcaini, Luca, Merlini, Giampaolo, Palladini, Giovanni, Nuvolone, Mario

Volltext

Touch, act and go: landing and operating on nucleosomes von Speranzini, Valentina, Pilotto, Simona, Sixma, Titia K, Mattevi, Andrea

Volltext

Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter von Schulte, Tim, Chaves-Sanjuan, Antonio, Mazzini, Giulia, Speranzini, Valentina, Lavatelli, Francesca, Ferri, Filippo, Palizzotto, Carlo, Mazza, Maria, Milani, Paolo, Nuvolone, Mario, Vogt, Anne-Cathrine, Vogel, Monique, Palladini, Giovanni, Merlini, Giampaolo, Bolognesi, Martino, Ferro, Silvia, Zini, Eric, Ricagno, Stefano

Volltext

Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models von Jasmine, Sumer, Mandl, Adel, Krueger, Timothy E. G., Dalrymple, Susan L., Antony, Lizamma, Dias, Jennifer, Celatka, Cassandra A., Tapper, Amy E., Kleppe, Maria, Kanayama, Mayuko, Jing, Yuezhou, Speranzini, Valentina, Wang, Yuzhuo Z., Luo, Jun, Trock, Bruce J., Denmeade, Samuel R., Carducci, Michael A., Mattevi, Andrea, Rienhoff, Hugh Y., Isaacs, John T., Brennen, W. Nathaniel

Volltext

Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids von Marchetti, Marialaura, Liuzzi, Anastasia, Fermi, Beatrice, Corsini, Romina, Folli, Claudia, Speranzini, Valentina, Gandolfi, Francesco, Bettati, Stefano, Ronda, Luca, Cendron, Laura, Berni, Rodolfo, Zanotti, Giuseppe, Percudani, Riccardo

Volltext

Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features von Speranzini, Valentina, Rotili, Dante, Ciossani, Giuseppe, Pilotto, Simona, Marrocco, Biagina, Forgione, Mariantonietta, Lucidi, Alessia, Forneris, Federico, Mehdipour, Parinaz, Velankar, Sameer, Mai, Antonello, Mattevi, Andrea

Volltext

Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation von Broggini, Luca, Barzago, Maria Monica, Speranzini, Valentina, Schulte, Tim, Sonzini, Federica, Giono, Matteo, Romeo, Margherita, Milani, Paolo, Caminito, Serena, Mazzini, Giulia, Rognoni, Paola, Merlini, Giampaolo, Pappone, Carlo, Anastasia, Luigi, Nuvolone, Mario, Palladini, Giovanni, Diomede, Luisa, Ricagno, Stefano

Volltext bestellen