Central venous catheter insertion by a clinical nurse consultant or anaesthetic medical staff: a single-centre observational study von Yacopetti, Nic, Alexandrou, Evan, Spencer, Tim R, Frost, Steven A, Davidson, Patricia M, O'Sullivan, Greg, Hillman, Ken M

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Clonal dynamics of haematopoiesis across the human lifespan von Mitchell, Emily, Spencer Chapman, Michael, Williams, Nicholas, Dawson, Kevin J., Mende, Nicole, Calderbank, Emily F., Jung, Hyunchul, Mitchell, Thomas, Coorens, Tim H. H., Spencer, David H., Machado, Heather, Lee-Six, Henry, Davies, Megan, Hayler, Daniel, Fabre, Margarete A., Mahbubani, Krishnaa, Abascal, Federico, Cagan, Alex, Vassiliou, George S., Baxter, Joanna, Martincorena, Inigo, Stratton, Michael R., Kent, David G., Chatterjee, Krishna, Parsy, Kourosh Saeb, Green, Anthony R., Nangalia, Jyoti, Laurenti, Elisa, Campbell, Peter J.

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Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia von Paris, Jasmin, Morgan, Marcos, Campos, Joana, Spencer, Gary J., Shmakova, Alena, Ivanova, Ivayla, Mapperley, Christopher, Lawson, Hannah, Wotherspoon, David A., Sepulveda, Catarina, Vukovic, Milica, Allen, Lewis, Sarapuu, Annika, Tavosanis, Andrea, Guitart, Amelie V., Villacreces, Arnaud, Much, Christian, Choe, Junho, Azar, Ali, van de Lagemaat, Louie N., Vernimmen, Douglas, Nehme, Ali, Mazurier, Frederic, Somervaille, Tim C.P., Gregory, Richard I., O’Carroll, Dónal, Kranc, Kamil R.

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Extensive phylogenies of human development inferred from somatic mutations von Coorens, Tim H. H., Moore, Luiza, Robinson, Philip S., Sanghvi, Rashesh, Christopher, Joseph, Hewinson, James, Przybilla, Moritz J., Lawson, Andrew R. J., Spencer Chapman, Michael, Cagan, Alex, Oliver, Thomas R. W., Neville, Matthew D. C., Hooks, Yvette, Noorani, Ayesha, Mitchell, Thomas J., Fitzgerald, Rebecca C., Campbell, Peter J., Martincorena, Iñigo, Rahbari, Raheleh, Stratton, Michael R.

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Somatic mutation landscapes at single-molecule resolution von Abascal, Federico, Harvey, Luke M. R., Mitchell, Emily, Lawson, Andrew R. J., Lensing, Stefanie V., Ellis, Peter, Russell, Andrew J. C., Alcantara, Raul E., Baez-Ortega, Adrian, Wang, Yichen, Kwa, Eugene Jing, Lee-Six, Henry, Cagan, Alex, Coorens, Tim H. H., Chapman, Michael Spencer, Olafsson, Sigurgeir, Leonard, Steven, Jones, David, Machado, Heather E., Davies, Megan, Øbro, Nina F., Mahubani, Krishnaa T., Allinson, Kieren, Gerstung, Moritz, Saeb-Parsy, Kourosh, Kent, David G., Laurenti, Elisa, Stratton, Michael R., Rahbari, Raheleh, Campbell, Peter J., Osborne, Robert J., Martincorena, Iñigo

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The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells von Harris, William J., Huang, Xu, Lynch, James T., Spencer, Gary J., Hitchin, James R., Li, Yaoyong, Ciceri, Filippo, Blaser, Julian G., Greystoke, Brigit F., Jordan, Allan M., Miller, Crispin J., Ogilvie, Donald J., Somervaille, Tim C.P.

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Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia von Maiques-Diaz, Alba, Spencer, Gary J., Lynch, James T., Ciceri, Filippo, Williams, Emma L., Amaral, Fabio M.R., Wiseman, Daniel H., Harris, William J., Li, Yaoyong, Sahoo, Sudhakar, Hitchin, James R., Mould, Daniel P., Fairweather, Emma E., Waszkowycz, Bohdan, Jordan, Allan M., Smith, Duncan L., Somervaille, Tim C.P.

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A marine microbiome antifungal targets urgent-threat drug-resistant fungi von Zhang, Fan, Zhao, Miao, Braun, Doug R, Ericksen, Spencer S, Piotrowski, Jeff S, Nelson, Justin, Peng, Jian, Ananiev, Gene E, Chanana, Shaurya, Barns, Kenneth, Fossen, Jen, Sanchez, Hiram, Chevrette, Marc G, Guzei, Ilia A, Zhao, Changgui, Guo, Le, Tang, Weiping, Currie, Cameron R, Rajski, Scott R, Audhya, Anjon, Andes, David R, Bugni, Tim S

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Dereplication of Natural Product Antifungals via Liquid Chromatography-Tandem Mass Spectrometry and Chemical Genomics von Brittin, Nathaniel J, Aceti, David J, Braun, Doug R, Anderson, Josephine M, Ericksen, Spencer S, Rajski, Scott R, Currie, Cameron R, Andes, David R, Bugni, Tim S

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Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event von Golubchik, Tanya, Brueggemann, Angela B, Street, Teresa, Gertz, Robert E, Spencer, Chris C A, Ho, Thien, Giannoulatou, Eleni, Link-Gelles, Ruth, Harding, Rosalind M, Beall, Bernard, Peto, Tim E A, Moore, Matthew R, Donnelly, Peter, Crook, Derrick W, Bowden, Rory

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A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival von Jude, J G, Spencer, G J, Huang, X, Somerville, T D D, Jones, D R, Divecha, N, Somervaille, T C P

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A source of systematic bias in self-reported physical activity: The cutpoint bias hypothesis von Olds, Tim S., Gomersall, Sjaan R., Olds, Spencer T., Ridley, Kate

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Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells von SOMERVAILLE, Tim C. P, MATHENY, Christina J, SPENCER, Gary J, IWASAKI, Masayuki, RINN, John L, WITTEN, Daniela M, CHANG, Howard Y, SHURTLEFF, Sheila A, DOWNING, James R, CLEARY, Michael L

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Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia von Deb, Gauri, Wingelhofer, Bettina, Amaral, Fabio M. R., Maiques-Diaz, Alba, Chadwick, John A., Spencer, Gary J., Williams, Emma L., Leong, Hui-Sun, Maes, Tamara, Somervaille, Tim C. P.

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Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies von Nicosia, Luciano, Spencer, Gary J, Brooks, Nigel, Amaral, Fabio M R, Basma, Naseer J, Chadwick, John A, Revell, Bradley, Wingelhofer, Bettina, Maiques-Diaz, Alba, Sinclair, Oliver, Camera, Francesco, Ciceri, Filippo, Wiseman, Daniel H, Pegg, Neil, West, Will, Knurowski, Tomasz, Frese, Kris, Clegg, Karen, Campbell, Victoria L, Cavet, James, Copland, Mhairi, Searle, Emma, Somervaille, Tim C P

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Effects of Standard and Modular Psychotherapies in the Treatment of Youth With Severe Irritability von Evans, Spencer C, Weisz, John R, Carvalho, Ana C, Garibaldi, Patricia M, Bearman, Sarah Kate, Chorpita, Bruce F

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Tetrodotoxin‐resistant mechanosensitivity and L‐type calcium channel‐mediated spontaneous calcium activity in enteric neurons von Amedzrovi Agbesi, Richard J., El Merhie, Amira, Spencer, Nick J., Hibberd, Tim, Chevalier, Nicolas R.

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Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia von Simeoni, Fabrizio, Romero-Camarero, Isabel, Camera, Francesco, Amaral, Fabio M.R., Sinclair, Oliver J., Papachristou, Evangelia K., Spencer, Gary J., Lie-A-Ling, Michael, Lacaud, Georges, Wiseman, Daniel H., Carroll, Jason S., Somervaille, Tim C.P.

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HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block von Maiques-Diaz, Alba, Nicosia, Luciano, Basma, Naseer J., Romero-Camarero, Isabel, Camera, Francesco, Spencer, Gary J., Amaral, Fabio M. R., Simeoni, Fabrizio, Wingelhofer, Bettina, Williamson, Andrew J. K., Pierce, Andrew, Whetton, Anthony D., Somervaille, Tim C. P.

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Reconstructing phylogenetic trees from genome-wide somatic mutations in clonal samples von Coorens, Tim H. H., Spencer Chapman, Michael, Williams, Nicholas, Martincorena, Inigo, Stratton, Michael R., Nangalia, Jyoti, Campbell, Peter J.

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