Engineered dual selection for directed evolution of SpCas9 PAM specificity von Goldberg, Gregory W., Spencer, Jeffrey M., Giganti, David O., Camellato, Brendan R., Agmon, Neta, Ichikawa, David M., Boeke, Jef D., Noyes, Marcus B.

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Deep mutational scanning of S. pyogenes Cas9 reveals important functional domains von Spencer, Jeffrey M., Zhang, Xiaoliu

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A universal deep-learning model for zinc finger design enables transcription factor reprogramming von Ichikawa, David M., Abdin, Osama, Alerasool, Nader, Kogenaru, Manjunatha, Mueller, April L., Wen, Han, Giganti, David O., Goldberg, Gregory W., Adams, Samantha, Spencer, Jeffrey M., Razavi, Rozita, Nim, Satra, Zheng, Hong, Gionco, Courtney, Clark, Finnegan T., Strokach, Alexey, Hughes, Timothy R., Lionnet, Timothee, Taipale, Mikko, Kim, Philip M., Noyes, Marcus B.

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GLUT12 promotes prostate cancer cell growth and is regulated by androgens and CaMKK2 signaling von White, Mark A, Tsouko, Efrosini, Lin, Chenchu, Rajapakshe, Kimal, Spencer, Jeffrey M, Wilkenfeld, Sandi R, Vakili, Sheiva S, Pulliam, Thomas L, Awad, Dominik, Nikolos, Fotis, Katreddy, Rajasekhara Reddy, Kaipparettu, Benny Abraham, Sreekumar, Arun, Zhang, Xiaoliu, Cheung, Edwin, Coarfa, Cristian, Frigo, Daniel E

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The geometric influence on the Cys2His2 zinc finger domain and functional plasticity von Mueller, April L, Corbi-Verge, Carles, Giganti, David O, Ichikawa, David M, Spencer, Jeffrey M, MacRae, Mark, Garton, Michael, Kim, Philip M, Noyes, Marcus B

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141. A Screening Platform for Generating Cas9 Mutants with Improved Function von Spencer, Jeffrey M., Zhang, Xiaoliu

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340. Development of a Nuclease Screen to Improve Cas9 Targeting Specificity von Spencer, Jeffrey M., Zhang, Xiaoliu

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575. Complete Removal of E-Cadherin from 4T-1 Murine Breast Cancer Cells Has No Effect on Metastasis von Spencer, Jeffrey M., Rivera, Armando, Zhang, Xiaoliu

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The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis von Scofield, M D, Heinsbroek, J A, Gipson, C D, Kupchik, Y M, Spencer, S, Smith, A C W, Roberts-Wolfe, D, Kalivas, P W

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Agriculture production as a major driver of the Earth system exceeding planetary boundaries von Campbell, Bruce M., Beare, Douglas J., Bennett, Elena M., Hall-Spencer, Jason M., Ingram, John S. I., Jaramillo, Fernando, Ortiz, Rodomiro, Ramankutty, Navin, Sayer, Jeffrey A., Shindell, Drew

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Mere Belonging: The Power of Social Connections von Walton, Gregory M., Cohen, Geoffrey L., Cwir, David, Spencer, Steven J.

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Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysi... von McQuade, Jennifer L, Daniel, Carrie R, Hess, Kenneth R, Mak, Carmen, Wang, Daniel Y, Rai, Rajat R, Park, John J, Haydu, Lauren E, Spencer, Christine, Wongchenko, Matthew, Lane, Stephen, Lee, Dung-Yang, Kaper, Mathilde, McKean, Meredith, Beckermann, Kathryn E, Rubinstein, Samuel M, Rooney, Isabelle, Musib, Luna, Budha, Nageshwar, Hsu, Jessie, Nowicki, Theodore S, Avila, Alexandre, Haas, Tomas, Puligandla, Maneka, Lee, Sandra, Fang, Shenying, Wargo, Jennifer A, Gershenwald, Jeffrey E, Lee, Jeffrey E, Hwu, Patrick, Chapman, Paul B, Sosman, Jeffrey A, Schadendorf, Dirk, Grob, Jean-Jacques, Flaherty, Keith T, Walker, Dana, Yan, Yibing, McKenna, Edward, Legos, Jeffrey J, Carlino, Matteo S, Ribas, Antoni, Kirkwood, John M, Long, Georgina V, Johnson, Douglas B, Menzies, Alexander M, Davies, Michael A

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COVID-SCORE: A global survey to assess public perceptions of government responses to COVID-19 (COVID-SCORE-10) von Lazarus, Jeffrey V, Ratzan, Scott, Palayew, Adam, Billari, Francesco C, Binagwaho, Agnes, Kimball, Spencer, Larson, Heidi J, Melegaro, Alessia, Rabin, Kenneth, White, Trenton M, El-Mohandes, Ayman

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COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide von El-Mohandes, Ayman, White, Trenton M., Wyka, Katarzyna, Rauh, Lauren, Rabin, Kenneth, Kimball, Spencer H., Ratzan, Scott C., Lazarus, Jeffrey V.

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Quantifying the inhibitory impact of soluble phenolics on anaerobic carbon mineralization in a thawing permafrost peatland von Cory, Alexandra B, Chanton, Jeffrey P, Spencer, Robert G M, Ogles, Olivia C, Rich, Virginia I, McCalley, Carmody K, Wilson, Rachel M

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Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy von Brantly, Mark L, Chulay, Jeffrey D, Wang, Lili, Mueller, Christian, Humphries, Margaret, Spencer, L. Terry, Rouhani, Farshid, Conlon, Thomas J, Calcedo, Roberto, Betts, Michael R, Spencer, Carolyn, Byrne, Barry J, Wilson, James M, Flotte, Terence R

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The future of Blue Carbon science von Macreadie, Peter I., Anton, Andrea, Raven, John A., Beaumont, Nicola, Connolly, Rod M., Friess, Daniel A., Kelleway, Jeffrey J., Kennedy, Hilary, Kuwae, Tomohiro, Lavery, Paul S., Lovelock, Catherine E., Smale, Dan A., Apostolaki, Eugenia T., Atwood, Trisha B., Baldock, Jeff, Bianchi, Thomas S., Chmura, Gail L., Eyre, Bradley D., Fourqurean, James W., Hall-Spencer, Jason M., Huxham, Mark, Hendriks, Iris E., Krause-Jensen, Dorte, Laffoley, Dan, Luisetti, Tiziana, Marbà, Núria, Masque, Pere, McGlathery, Karen J., Megonigal, J. Patrick, Murdiyarso, Daniel, Russell, Bayden D., Santos, Rui, Serrano, Oscar, Silliman, Brian R., Watanabe, Kenta, Duarte, Carlos M.

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An organization‐ and category‐level comparison of diagnostic requirements for mental disorders in ICD‐11 and DSM‐5 von First, Michael B., Gaebel, Wolfgang, Maj, Mario, Stein, Dan J., Kogan, Cary S., Saunders, John B., Poznyak, Vladimir B., Gureje, Oye, Lewis‐Fernández, Roberto, Maercker, Andreas, Brewin, Chris R., Cloitre, Marylene, Claudino, Angelica, Pike, Kathleen M., Baird, Gillian, Skuse, David, Krueger, Richard B., Briken, Peer, Burke, Jeffrey D., Lochman, John E., Evans, Spencer C., Woods, Douglas W., Reed, Geoffrey M.

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Microbiological and Nutritional Analysis of Lettuce Crops Grown on the International Space Station von Khodadad, Christina L M, Hummerick, Mary E, Spencer, LaShelle E, Dixit, Anirudha R, Richards, Jeffrey T, Romeyn, Matthew W, Smith, Trent M, Wheeler, Raymond M, Massa, Gioia D

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Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, pha... von Amaria, Rodabe N, Prieto, Peter A, Tetzlaff, Michael T, Reuben, Alexandre, Andrews, Miles C, Ross, Merrick I, Glitza, Isabella C, Cormier, Janice, Hwu, Wen-Jen, Tawbi, Hussein A, Patel, Sapna P, Lee, Jeffrey E, Gershenwald, Jeffrey E, Spencer, Christine N, Gopalakrishnan, Vancheswaran, Bassett, Roland, Simpson, Lauren, Mouton, Rosalind, Hudgens, Courtney W, Zhao, Li, Zhu, Haifeng, Cooper, Zachary A, Wani, Khalida, Lazar, Alexander, Hwu, Patrick, Diab, Adi, Wong, Michael K, McQuade, Jennifer L, Royal, Richard, Lucci, Anthony, Burton, Elizabeth M, Reddy, Sangeetha, Sharma, Padmanee, Allison, James, Futreal, Phillip A, Woodman, Scott E, Davies, Michael A, Wargo, Jennifer A

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