The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion von Li, Ang, Dawson, John C., Forero-Vargas, Manuel, Spence, Heather J., Yu, Xinzi, König, Ireen, Anderson, Kurt, Machesky, Laura M.

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The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migration von Zech, Tobias, Calaminus, Simon D J, Caswell, Patrick, Spence, Heather J, Carnell, Michael, Insall, Robert H, Norman, Jim, Machesky, Laura M

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Loss of Scar/WAVE Complex Promotes N-WASP- and FAK-Dependent Invasion von Tang, Haoran, Li, Ang, Bi, Jing, Veltman, Douwe M., Zech, Tobias, Spence, Heather J., Yu, Xinzi, Timpson, Paul, Insall, Robert H., Frame, Margaret C., Machesky, Laura M.

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CYRI-B mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake von Nikolaou, Savvas, Juin, Amelie, Whitelaw, Jamie A, Paul, Nikki R, Fort, Loic, Nixon, Colin, Spence, Heather J, Bryson, Sheila, Machesky, Laura M

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Mtss1 promotes cell-cell junction assembly and stability through the small GTPase Rac1 von Dawson, John C, Bruche, Susann, Spence, Heather J, Braga, Vania M M, Machesky, Laura M

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Dichotomous role of the serine/threonine kinase MAP4K4 in pancreatic ductal adenocarcinoma onset and metastasis through control of AKT and ERK pathways von Juin, Amelie, Spence, Heather J, Machesky, Laura M

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Functional analysis of Dictyostelium IBARa reveals a conserved role of the I-BAR domain in endocytosis von Veltman, Douwe M, Auciello, Giulio, Spence, Heather J, Machesky, Laura M, Rappoport, Joshua Z, Insall, Robert H

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Dystroglycan, a scaffold for the ERK-MAP kinase cascade von Spence, Heather J, Dhillon, Amardeep S, James, Marian, Winder, Steven J

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Scar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions von Spence, Heather J, Timpson, Paul, Tang, Hao Ran, Insall, Robert H, Machesky, Laura M

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Collagen VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche von Papalazarou, Vasileios, Drew, James, Juin, Amelie, Spence, Heather J, Whitelaw, Jamie, Nixon, Colin, Salmeron-Sanchez, Manuel, Machesky, Laura M

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N-WASP Control of LPAR1 Trafficking Establishes Response to Self-Generated LPA Gradients to Promote Pancreatic Cancer Cell Metastasis von Juin, Amelie, Spence, Heather J., Martin, Kirsty J., McGhee, Ewan, Neilson, Matthew, Cutiongco, Marie F.A., Gadegaard, Nikolaj, Mackay, Gillian, Fort, Loic, Lilla, Sergio, Kalna, Gabriela, Thomason, Peter, Koh, Yvette W.H., Norman, Jim C., Insall, Robert H., Machesky, Laura M.

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Fam49/CYRI interacts with Rac1 and locally suppresses protrusions von Fort, Loic, Batista, José Miguel, Thomason, Peter A., Spence, Heather J., Whitelaw, Jamie A., Tweedy, Luke, Greaves, Jennifer, Martin, Kirsty J., Anderson, Kurt I., Brown, Peter, Lilla, Sergio, Neilson, Matthew P., Tafelmeyer, Petra, Zanivan, Sara, Ismail, Shehab, Bryant, David M., Tomkinson, Nicholas C. O., Chamberlain, Luke H., Mastick, Grant S., Insall, Robert H., Machesky, Laura M.

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BTB-Kelch protein Krp1 regulates proliferation and differentiation of myoblasts von Paxton, Camille W, Cosgrove, Ruth A, Drozd, Anja C, Wiggins, Emma L, Woodhouse, Sam, Watson, Rachel A, Spence, Heather J, Ozanne, Brad W, Pell, Jennifer M

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Rab25 Associates with α5β1 Integrin to Promote Invasive Migration in 3D Microenvironments von Caswell, Patrick T., Spence, Heather J., Parsons, Maddy, White, Dominic P., Clark, Katherine, Cheng, Kwai Wa, Mills, Gordon B., Humphries, Martin J., Messent, Anthea J., Anderson, Kurt I., McCaffrey, Mary W., Ozanne, Bradford W., Norman, Jim C.

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Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin von Woodham, Emma F., Paul, Nikki R., Tyrrell, Benjamin, Spence, Heather J., Swaminathan, Karthic, Scribner, Michelle R., Giampazolias, Evangelos, Hedley, Ann, Clark, William, Kage, Frieda, Marston, Daniel J., Hahn, Klaus M., Tait, Stephen W.G., Larue, Lionel, Brakebusch, Cord H., Insall, Robert H., Machesky, Laura M.

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Loss of N‐WASP drives early progression in an Apc model of intestinal tumourigenesis von Morris, Hayley T, Fort, Loic, Spence, Heather J, Patel, Rachana, Vincent, David F, Park, James H, Snapper, Scott B, Carey, Francis A, Sansom, Owen J, Machesky, Laura M

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AP-1 Differentially Expressed Proteins Krp1 and Fibronectin Cooperatively Enhance Rho-ROCK-Independent Mesenchymal Invasion by Altering the Function, Localization, and Activity of... von Spence, Heather J., McGarry, Lynn, Chew, Catherine S., Carragher, Neil O., Scott-Carragher, Linda A., Yuan, Zhengqiang, Croft, Daniel R., Olson, Michael F., Frame, Margaret, Ozanne, Bradford W.

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Muscular dystrophies, the cytoskeleton and cell adhesion von Spence, Heather J., Chen, Yun-Ju, Winder, Steven J.

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Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour von Tyrrell, Benjamin J., Woodham, Emma F., Spence, Heather J., Strathdee, Douglas, Insall, Robert H., Machesky, Laura M.

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Novel β-Propeller of the BTB-Kelch Protein Krp1 Provides a Binding Site for Lasp-1 That Is Necessary for Pseudopodial Extension von Gray, Christopher H., McGarry, Lynn C., Spence, Heather J., Riboldi-Tunnicliffe, Alan, Ozanne, Bradford W.

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