ISOWN: accurate somatic mutation identification in the absence of normal tissue controls von Kalatskaya, Irina, Trinh, Quang M, Spears, Melanie, McPherson, John D, Bartlett, John M S, Stein, Lincoln

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Deregulation of the spindle assembly checkpoint is associated with paclitaxel resistance in ovarian cancer von Chong, Taryne, Sarac, Amila, Yao, Cindy Q, Liao, Linda, Lyttle, Nicola, Boutros, Paul C, Bartlett, John M S, Spears, Melanie

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In situ detection of HER2:HER2 and HER2:HER3 protein–protein interactions demonstrates prognostic significance in early breast cancer von Spears, Melanie, Taylor, Karen J., Munro, Alison F., Cunningham, Carrie A., Mallon, Elizabeth A., Twelves, Chris J., Cameron, David A., Thomas, Jeremy, Bartlett, John M. S.

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Proximity ligation assays for isoform-specific Akt activation in breast cancer identify activated Akt1 as a driver of progression von Spears, Melanie, Cunningham, Carrie A, Taylor, Karen J, Mallon, Elizabeth A, Thomas, Jeremy St J, Kerr, Gillian R, Jack, Wilma JL, Kunkler, Ian H, Cameron, David A, Chetty, Udi, Bartlett, John MS

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Abstract A03: Evaluation of the Oncomine Pan-Cancer Cell-Free Assay for liquid biopsy profiling von Bayani, Jane, Hopkins, Megan, Spears, Melanie, Bartlett, John M. S.

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BIOM-25. MOLECULAR PROFILING PREDICTS EARLY AND LATE PROGRESSION IN GLIOBLASTOMA von Nikolopoulos, Marina, Wu, Megan, Bahcheli, Alexander, Kellett, Sorcha, Myrehaug, Sten, Sahgal, Arjun, Spears, Melanie, Pai, Shraddha, Bayani, Jane, Das, Sunit

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Abstract 2701: Molecular profiling to assess the immune response to neoadjuvant SABR in early breast cancer von Spears, Melanie, Talebian, Vida, Liao, Linda, Hopkins, Megan, Lynn, Kalan, Lock, Michael, Kornecki, Anat, Bartlett, John M., Brackstone, Muriel

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Abstract PD2-10: Predicting sensitivity to CDK4/6 inhibition in ER+/HER2- breast cancer cell lines von Bathurst, Lauren, Liao, Linda, Crozier, Cheryl, Bayani, Jane, Bartlett, John, Spears, Melanie

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Abstract 3571: Precise somatic mutation prediction in the absence of matching normal DNA von Kalatskaya, Irina, Trinh, Quang, Spears, Melanie, Bartlett, John, Stein, Lincoln

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Benchmarking to the Gold Standard: Hyaluronan‐Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture von Baker, Alexander E. G., Bahlmann, Laura C., Tam, Roger Y., Liu, Jeffrey C., Ganesh, Ahil N., Mitrousis, Nikolaos, Marcellus, Richard, Spears, Melanie, Bartlett, John M. S., Cescon, David W., Bader, Gary D., Shoichet, Molly S.

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Intratumoral (IT) INT230-6 can cause tumor necrosis in vivo: Preliminary results of a phase II randomized presurgical window-of-opportunity study in early breast cancers (the INVIN... von Arnaout, Angel, Spears, Melanie, Awan, Arif Ali, Robertson, Susan, Keyhanian, Kianoosh, Pond, Gregory Russell, Bartlett, John, Lopez-Ozuna, Vanessa, Mahmood, Syed, Bender, Lewis H., Walters, Ian B.

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Abstract PO-075: Performance comparison of five extraction kits for SARS-CoV-2 RNA extraction von Lungu, Ilinca M., De Luca, Angela, Li, Jason, Bayani, Jane, Spears, Melanie, Pugh, Trevor J., Bartlett, John M.S.

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Phase II randomized window of opportunity trial evaluating cytotoxic and immunomodulatory effects of intratumoral INT230-6 in early stage breast cancer: The INVINCIBLE trial von Spears, Melanie, Hopkins, Megan, Keyhanian, Kianoosh, Robertson, Susan, Liao, Linda, Talebian, Vida, Awan, Arif Ali, Pond, Gregory Russell, Bartlett, John, Bender, Lewis H., Walters, Ian B., Lopez-Ozuna, Vanessa, Arnaout, Angel

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Abstract 2726: Characterization of immune microenvironment and heterogeneity in breast cancer subtypes von Jain, Drashti, Liao, Linda, Hopkins, Megan, Quintayo, Mary Anne, Talebian, Vida, Bayani, Jane, Cheung, Alison, Yaffe, Martin, Bartlett, John, Spears, Melanie

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Abstract 2698: Spatial gene expression profiling in breast cancer von Spears, Melanie, Talebian, Vida, Liao, Linda, Hopkins, Megan, Jain, Drashti, Quintayo, Mary Anne, Bayani, Jane, Cheung, Alison, Yaffe, Martin, Bartlett, John M.

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Abstract P1-10-08: Assessing immune biomarkers of response to anthracyclines in breast cancer von Spears, Melanie, Denkert, Carsten, Villagas, Sonia L, Lyttle, Nicola, Liao, Linda, Quintayo, Mary Anne, Twelves, Christopher J

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Abstract P6-03-21: Identification of mechanisms driving acquired chemoresistance in preclinical breast cancer models of taxane resistance von Taylor, Karen J, Lyttle, Nicola, Lao, Linda, Gourley, Charlie, Cameron, David A, Bartlett, John MS, Spears, Melanie

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Assessment of risk of overall and late distant recurrence by Breast Cancer Index in postmenopausal women with early-stage, HR+ breast cancer in the TEAM trial von Bartlett, John MS, Xu, Keying, Wong, Jenna, Pond, Gregory Russell, Zhang, Yi, Spears, Melanie, Salunga, Ranelle C., Mallon, Elizabeth, Taylor, Karen J, Hasenburg, Annette, Markopoulos, Christos, Dirix, Luc Yves, Seynaeve, Caroline M., Van De Velde, Cornelis J.H., Rea, Daniel William, Schnabel, Catherine A, Treuner, Kai, Bayani, Jane

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Does RSClin provide additional information over classic clinico-pathologic scores (PREDICT 2.1, Influence, CTS-5)? A TEAM Pathology substudy von Beltran-Bless, Ana-Alicia, Pond, Gregory Russell, Bayani, Jane, Barker, Sarah, Spears, Melanie, Mallon, Elizabeth, Taylor, Karen J, Hasenburg, Annette, Markopoulos, Christos, Dirix, Luc Yves, Seynaeve, Caroline M., Van De Velde, Cornelis J.H., Rea, Daniel William, Vandermeer, Lisa, Hilton, John Frederick, Bartlett, John, Clemons, Mark J.

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Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study von Acs, Balazs, Leung, Samuel C.Y., Augulis, Renaldas, Bai, Yalai, Bane, Anita L., Bartlett, John M.S., Bayani, Jane, Bigras, Gilbert, Buikema, Henk, Chang, Martin C., Fineberg, Susan, Focke, Cornelia M., Gao, Dongxia, Gown, Allen M., Gutierrez, Carolina, Kos, Zuzana, Lænkholm, Anne-Vibeke, Laurinavicius, Arvydas, Levenson, Richard M., Mahboubi-Ardakani, Rustin, Mastropasqua, Mauro G., Osborne, C. Kent, Penault-Llorca, Frédérique M., Piper, Tammy, Quintayo, Mary Anne, Rau, Tilman T., Reinhard, Stefan, Robertson, Stephanie, Salgado, Roberto, Sugie, Tomoharu, van der Vegt, Bert, Viale, Giuseppe, Zabaglo, Lila A., Hayes, Daniel F., Rimm, David L., Dowsett, Mitch, Hayes, Daniel F., McShane, Lisa M., Nielsen, Torsten, Leung, Samuel, Acs, Balazs, Arun, Indu, Augulis, Renaldas, Badve, Sunil S., Bai, Yalai, Bane, Anita L., Bartlett, John M.S., Bayani, Jane, Bigras, Gilbert, Blank, Annika, Buikema, Henk, Chan, Angela, Chang, Martin C., Dodson, Andrew, Ehinger, Anna, Ellis, Matthew, Flowers, Margaret, Focke, Cornelia M., Galderisi, Chad, Gholap, Abhi, Gown, Allen M., Gutierrez, Carolina, Hartman, Douglas J., Hartman, Johan, Hugh, Judith C., Jadhav, Anagha, Kornaga, Elizabeth N., Kreipe, Hans, Lænkholm, Anne-Vibeke, Laurinavicius, Arvydas, Levenson, Richard, Mastropasqua, Mauro, Moriya, Takuya, Nofech-Mozes, Sharon, Osborne, C. Kent, Pan, Hongchao, Pantanowitz, Liron, Penault-Llorca, Frédérique M., Polley, Mei-Yin, Piper, Tammy, Quintayo, Mary Anne, Rau, Tilman T., Rimm, David L., Reinhard, Stefan, Robertson, Stephanie, Ruan, Jason, Salgado, Roberto, Shepherd, Lois, Smith, Ian, Sparano, Joseph, Spears, Melanie, Sugie, Tomoharu, Todd, Austin, van der Vegt, Bert, Viale, Giuseppe, Virk, Shakeel, Wang, Yihong, Yang, Hua, Zhang, Zhiwei, Zlobec, Inti

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