GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes von Sparsø, T, Andersen, G, Nielsen, T, Burgdorf, K. S, Gjesing, A. P, Nielsen, A. L, Albrechtsen, A, Rasmussen, S. S, Jørgensen, T, Borch-Johnsen, K, Sandbæk, A, Lauritzen, T, Madsbad, S, Hansen, T, Pedersen, O

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Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes von Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T., Li, Q., Nie, C., Wu, R., Morris, A. P., Ladenvall, C., Cauchi, S., Stančáková, A., Andersen, G., Astrup, A., Banasik, K., Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, J. M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liao, Q., Liu, X., Ma, T., Ma, X., Marre, M., Mokrosiński, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, T. W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., van’t Riet, E., van Leeuwen, N., Varga, T. V., Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., ‘t Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, T., Wang, J., Nielsen, R., Pedersen, O.

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Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release von Nielsen, T., Sparsø, T., Grarup, N., Jørgensen, T., Pisinger, C., Witte, D. R., Hansen, T., Pedersen, O.

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diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals von Grarup, N, Overvad, M, Sparsø, T, Witte, D. R, Pisinger, C, Jørgensen, T, Yamauchi, T, Hara, K, Maeda, S, Kadowaki, T, Hansen, T, Pedersen, O

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Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome von Starnawska, A, Hansen, C S, Sparsø, T, Mazin, W, Olsen, L, Bertalan, M, Buil, A, Bybjerg-Grauholm, J, Bækvad-Hansen, M, Hougaard, D M, Mortensen, P B, Pedersen, C B, Nyegaard, M, Werge, T, Weinsheimer, S

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Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction von Sparsø, T, Grarup, N, Andreasen, C, Albrechtsen, A, Holmkvist, J, Andersen, G, Jørgensen, T, Borch-Johnsen, K, Sandbæk, A, Lauritzen, T, Madsbad, S, Hansen, T, Pedersen, O

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Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation von Sparsø, T, Andersen, G, Albrechtsen, A, Jørgensen, T, Borch-Johnsen, K, Sandbæk, A, Lauritzen, T, Wasson, J, Permutt, M. A, Glaser, B, Madsbad, S, Pedersen, O, Hansen, T

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Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes von Snogdal, L. S., Wod, M., Grarup, N., Vestmar, M., Sparsø, T., Jørgensen, T., Lauritzen, T., Beck-Nielsen, H., Henriksen, J. E., Pedersen, O., Hansen, T., Højlund, K.

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Erratum to: Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release von Nielsen, T., Sparsø, T., Grarup, N., Jørgensen, T., Pisinger, C., Witte, D. R., Hansen, T., Pedersen, O.

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Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes von Larsen, L.H, Rose, C.S, Sparso, T, Overgaard, J, Torekov, S.S, Grarup, N, Jensen, D.P, Albrechtsen, A, Andersen, G, Ek, J

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A −243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subj... von Boesgaard, T. W., Castella, S. I., Andersen, G., Albrechtsen, A., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, O.

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Large-scale study of the −232C > G polymorphism of PCK1 in Type 2 diabetes von Wegner, L., Andersen, G., Albrechtsen, A., Sparsø, T., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, O.

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The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes von Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. P., Nielsen, A. L., Albrechtsen, A., Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O.

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The effect of GWAS identified BMI loci on changes in body weight among middle‐aged danes during a five‐year period von Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel‐Madsen, R., Sparso, T., Justesen, J. M., Harder, M. N., Jørgensen, T., Hansen, T., Pedersen, O.

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The Lin28/let-7 Axis Regulates Glucose Metabolism von Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.

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Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians von Cho, Yoon Shin, Chen, Chien-Hsiun, Hu, Cheng, Long, Jirong, Hee Ong, Rick Twee, Sim, Xueling, Takeuchi, Fumihiko, Wu, Ying, Go, Min Jin, Yamauchi, Toshimasa, Chang, Yi-Cheng, Kwak, Soo Heon, Ma, Ronald C W, Yamamoto, Ken, Adair, Linda S, Aung, Tin, Cai, Qiuyin, Chang, Li-Ching, Chen, Yuan-Tsong, Gao, Yutang, Hu, Frank B, Kim, Hyung-Lae, Kim, Sangsoo, Kim, Young Jin, Lee, Jeannette Jen-Mai, Lee, Nanette R, Li, Yun, Liu, Jian Jun, Lu, Wei, Nakamura, Jiro, Nakashima, Eitaro, Ng, Daniel Peng-Keat, Tay, Wan Ting, Tsai, Fuu-Jen, Wong, Tien Yin, Yokota, Mitsuhiro, Zheng, Wei, Zhang, Rong, Wang, Congrong, So, Wing Yee, Ohnaka, Keizo, Ikegami, Hiroshi, Hara, Kazuo, Cho, Young Min, Cho, Nam H, Chang, Tien-Jyun, Bao, Yuqian, Hedman, Åsa K, Morris, Andrew P, McCarthy, Mark I, Takayanagi, Ryoichi, Park, Kyong Soo, Jia, Weiping, Chuang, Lee-Ming, Chan, Juliana C N, Maeda, Shiro, Kadowaki, Takashi, Lee, Jong-Young, Wu, Jer-Yuarn, Teo, Yik Ying, Tai, E Shyong, Shu, Xiao Ou, Mohlke, Karen L, Kato, Norihiro, Han, Bok-Ghee, Seielstad, Mark

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Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma von Chambers, John C, Zhang, Weihua, Li, Xinzhong, Wass, Mark N, Holm, Hilma, Sanna, Serena, Kavousi, Maryam, Coin, Lachlan J, Deng, Guohong, Gieger, Christian, Kühnel, Brigitte, Kumar, Vinod, Lagou, Vasiliki, Luan, Jian'an, Vidal, Pedro Marques, Peden, John F, Rahmioglu, Nilufer, Soininen, Pasi, Speliotes, Elizabeth K, Yuan, Xin, Alizadeh, Behrooz Z, Atwood, Larry D, Borecki, Ingrid B, Brown, Morris J, Charoen, Pimphen, Cucca, Francesco, Das, Debashish, de Geus, Eco J C, Dixon, Anna L, Döring, Angela, Ehret, Georg, Eyjolfsson, Gudmundur I, Farrall, Martin, Forouhi, Nita G, Goessling, Wolfram, Harris, Tamara B, Heath, Simon, Hirschfield, Gideon M, Hofman, Albert, Homuth, Georg, Hyppönen, Elina, Janssen, Harry L A, Johnson, Toby, Kangas, Antti J, Kema, Ido P, Kühn, Jens P, Lai, Sandra, Lathrop, Mark, Lerch, Markus M, Li, Yun, Liang, T Jake, Lin, Jing-Ping, Loos, Ruth J F, Martin, Nicholas G, Moffatt, Miriam F, Musunuru, Kiran, Nakamura, Yusuke, O'Donnell, Christopher J, Pouta, Anneli, Prins, Bram P, Prokopenko, Inga, Puls, Ralf, Schlessinger, David, Schouten, Jeoffrey N L, Seedorf, Udo, Sen-Chowdhry, Srijita, Siminovitch, Katherine A, Spector, Timothy D, Teslovich, Tanya M, Tukiainen, Taru, Van der Klauw, Melanie M, Vasan, Ramachandran S, Wallaschofski, Henri, Wichmann, H-Erich, Willemsen, Gonneke, Würtz, Peter, Xu, Chun, Yerges-Armstrong, Laura M, Abecasis, Goncalo R, Ahmadi, Kourosh R, Caulfield, Mark, Cookson, William O, McCarthy, Mark I, Sternberg, Michael J E, Stolk, Ronald P, Thomas, Howard C, Uda, Manuela, Waeber, Gérard, Waterworth, Dawn M, Watkins, Hugh, Whitfield, John B, Witteman, Jacqueline C M, Wolffenbuttel, Bruce H R, Fox, Caroline S, Vollenweider, Peter, Völzke, Henry, Schadt, Eric E, Järvelin, Marjo-Riitta, Elliott, Paul, Kooner, Jaspal S

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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis von Stahl, Eli A, Wegmann, Daniel, Trynka, Gosia, Gutierrez-Achury, Javier, Do, Ron, Voight, Benjamin F, Kraft, Peter, Chen, Robert, Kallberg, Henrik J, Kurreeman, Fina A S, Kathiresan, Sekar, Wijmenga, Cisca, Gregersen, Peter K, Alfredsson, Lars, Siminovitch, Katherine A, Worthington, Jane, de Bakker, Paul I W, Raychaudhuri, Soumya, Plenge, Robert M

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Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes von STRAWBRIDGE, Rona J, DUPUIS, Josée, NICA, Alexandra, WHEELER, Eleanor, HAN CHEN, VOIGHT, Benjamin F, TANEERA, Jalal, KANONI, Stavroula, PEDEN, John F, TURRINI, Fabiola, GUSTAFSSON, Stefan, ZABENA, Carina, PROKOPENKO, Inga, ALMGREN, Peter, BARKER, David J. P, BARNES, Daniel, DENNISON, Elaine M, ERIKSSON, Johan G, ERIKSSON, Per, EURY, Elodie, FOLKERSEN, Lasse, FOX, Caroline S, FRAYLING, Timothy M, BARKER, Adam, GOEL, Anuj, GU, Harvest F, HORIKOSHI, Momoko, ISOMAA, Bo, JACKSON, Anne U, JAMESON, Karen A, KAJANTIE, Eero, KERR-CONTE, Julie, KUULASMAA, Teemu, KUUSISTO, Johanna, AHLQVIST, Emma, LOOS, Ruth J. F, JIAN'AN LUAN, MAKRILAKIS, Konstantinos, MANNING, Alisa K, MARTINEZ-LARRAD, Maria Teresa, NARISU, Narisu, MANNILA, Maria Nastase, OHRVIK, John, OSMOND, Clive, PASCOE, Laura, RYBIN, Denis, PAYNE, Felicity, SAYER, Avan A, SENNBLAD, Bengt, SILVEIRA, Angela, STANCAKOVA, Alena, STIRRUPS, Kathy, SWIFT, Amy J, SYVÄNEN, Ann-Christine, PETRIE, John R, TRAVERS, Mary E, BOUATIA-NAJI, Nabila, DIMAS, Antigone S

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Parental origin of sequence variants associated with complex diseases von Kong, Augustine, Steinthorsdottir, Valgerdur, Masson, Gisli, Thorleifsson, Gudmar, Sulem, Patrick, Besenbacher, Soren, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Kristinsson, Kari Th, Jonasdottir, Adalbjorg, Frigge, Michael L., Gylfason, Arnaldur, Olason, Pall I., Gudjonsson, Sigurjon A., Sverrisson, Sverrir, Stacey, Simon N., Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R., Sigurdsson, Helgi, Jonsson, Thorvaldur, Benediktsson, Rafn, Olafsson, Jon H., Johannsson, Oskar Th, Hreidarsson, Astradur B., Sigurdsson, Gunnar, Ferguson-Smith, Anne C., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Stefansson, Kari

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