1393 Discovery of PLX-4107, a selective IKZF2 molecular glue degrader, that modulates suppressive regulatory T cells and demonstrates anti-tumor activity von Thompson, Peggy A, Yang, Pengyu, Huang, Yujun, Song, Susan, Yang, Linette, Li, Xiaoming, Dearie, Alejandro, Chien, Stephen, Spalding, Mary E, Choi, Sean, Blanco, Gabrielle, Daniele, Elizabeth, Toth, Julia, Parker, Greg, Bailey, Simon

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Abstract B37: PLX-4107, a selective IKZF2 degrader, reprograms suppressive regulatory T cells and demonstrates anti-tumor activity von Thompson, Peggy A, Yang, Pengyu, Yang, Linette, Song, Susan, Huang, Yujun, Li, Xiaoming, Dearie, Alejandro, Chien, Stephen, Spalding, Mary E, Blanco, Gabrielle, Daniele, Elizabeth, Toth, Julia, Jamborcic, Aleksandar, Parker, Gregory, Bailey, Simon

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Abstract 421: PLX-3618, a potent, selective monovalent BRD4 degrader demonstrates activity in models of prostate cancer von Steadman, Kenneth, Parker, Gregory S., Leriche, Geoffray, Fish, Sarah, Toth, Julia, Spalding, Mary E., Daniele, Elizabeth, Jamborcic, Aleksandar, Li, Xiaoming, Kallel, E Adam, Barmare, Farhana, Chng, Kenneth, Green, Erika, Hocker, Michael, Imler, Elliot, Zhang, Yi, Thompson, Peggy A., Bailey, Simon

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Abstract 1111: Identification of selective IKZF2 degraders that reprogram suppressive regulatory T cells in solid tumors von Thompson, Peggy A., Yang, Pengyu, Li, Xiaoming, Chien, Stephen, Spalding, Mary E., Dearie, Alejandro, Daniele, Elizabeth, Yang, Linette, Kallel, E Adam, Jamborcic, Aleksandar, Toth, Julia, Parker, Gregory, Bailey, Simon

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Nebraska's groundwater legacy: Nitrate contamination beneath irrigated cropland von Exner, Mary E., Hirsh, Aaron J., Spalding, Roy F.

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Human Immunodeficiency Virus Type 1 Mutations Selected in Patients Failing Efavirenz Combination Therapy von BACHELER, L. T, ANTON, E. D, BECKER, M. F, LASUT, A. L, GEORGE, H. J, SPALDING, D. R, HOLLIS, G, ABREMSKI, K, KUDISH, P, BAKER, D, BUNVILLE, J, KRAKOWSKI, K, BOLLING, L, AUJAY, M, WANG, X. V, ELLIS, D

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Single low-dose targeted bevacizumab infusion in adult patients with steroid-refractory radiation necrosis of the brain: a phase II open-label prospective clinical trial von Dashti, Shervin R, Kadner, Robert J, Folley, Bradley S, Sheehan, Jason P, Han, Dong Y, Kryscio, Richard J, Carter, Mary B, Shields, Lisa B E, Plato, Brian M, La Rocca, Renato V, Spalding, Aaron C, Yao, Tom L, Fraser, Justin F

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Safer storage of firearms at home and risk of suicide: a study of protective factors in a nationally representative sample von Shenassa, Edmond D, Rogers, Michelle L, Spalding, Kirsten L, Roberts, Mary B

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Integrated Deep Soil N and Groundwater Isotope Investigation of N Sources Captured by Municipal Wells von Spalding, Roy F., Hirsh, Aaron J., Exner, Mary E., Stange, Marty, Aravena, Ramon

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Dialysis Water Supply Faucet as Reservoir for Carbapenemase-Producing Pseudomonas aeruginosa von Prestel, Christopher, Moulton-Meissner, Heather, Gable, Paige, Stanton, Richard A., Glowicz, Janet, Franco, Lauren, McConnell, Mary, Torres, Tiffany, John, Dijo, Blackwell, Gillian, Yates, Renae, Brown, Chavela, Reyes, Kristina, McAllister, Gillian A., Kunz, Jasen, Conners, Erin E., Benedict, Katharine M., Kirby, Amy, Mattioli, Mia, Xu, Kerui, Gualandi, Nicole, Booth, Stephanie, Novosad, Shannon, Arduino, Matthew, Halpin, Alison Laufer, Wells, Katherine, Walters, Maroya Spalding

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The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences von Drysdale, Rachel, Cook, Charles E, Petryszak, Robert, Baillie-Gerritsen, Vivienne, Barlow, Mary, Gasteiger, Elisabeth, Gruhl, Franziska, Haas, Jürgen, Lanfear, Jerry, Lopez, Rodrigo, Redaschi, Nicole, Stockinger, Heinz, Teixeira, Daniel, Venkatesan, Aravind, Blomberg, Niklas, Durinx, Christine, McEntyre, Johanna

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Gain-of-function signal transducer and activator of transcription 1 ( STAT1 ) mutation–related primary immunodeficiency is associated with disseminated mucormycosis von Kumar, Nilay, MD, Hanks, Mary E., BSc, Chandrasekaran, Prabha, PhD, Davis, Brian C., MD, Hsu, Amy P., BA, Van Wagoner, Nicholas J., MD, Merlin, Jessica S., MD, Spalding, Christine, BSc, La Hoz, Ricardo M., MD, Holland, Steven M., MD, Zerbe, Christa S., MD, Sampaio, Elizabeth P., MD, PhD

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Long-term response of groundwater nitrate concentrations to management regulations in Nebraska's central Platte valley von Exner, Mary E, Perea-Estrada, Hugo, Spalding, Roy F

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Controlling Nitrate Leaching in Irrigated Agriculture von Spalding, Roy F., Watts, Darrell G., Schepers, James S., Burbach, Mark E., Exner, Mary E., Poreda, Robert J., Martin, Glen E.

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Dialysis Water Supply Faucet as Reservoir for Carbapenemase-Producing Pseudomonas aeruginosa von Prestel, Christopher, Moulton-Meissner, Heather, Gable, Paige, Stanton, Richard A, Glowicz, Janet, Franco, Lauren, McConnell, Mary, Torres, Tiffany, John, Dijo, Blackwell, Gillian, Yates, Renae, Brown, Chavela, Reyes, Kristina, McAllister, Gillian A, Kunz, Jasen, Conners, Erin E, Benedict, Katharine M, Kirby, Amy, Mattioli, Mia, Xu, Kerui, Gualandi, Nicole, Booth, Stephanie, Novosad, Shannon, Arduino, Matthew, Halpin, Alison Laufer, Wells, Katherine, Walters, Maroya Spalding

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Race, Income, and Disease Outcomes in Juvenile Dermatomyositis von Phillippi, Kathryn, DO, Hoeltzel, Mark, MD, Byun Robinson, Angela, MD, MPH, Kim, Susan, MD, MMSc

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A-82 Neurocognitive Improvement after Intra-Arterial Bevacizumab for Steroid-Refractory Radiation Necrosis of the Brain von Folley, Bradley S, Kadner, Robert J, Sheehan, Jason P, Han, Dong Y, Kryscio, Richard J, Carter, Mary B, Shields, Lisa B E, Plato, Brian M, La Rocca, Renato V, Spalding, Aaron C, Yao, Tom L, Fraser, Justin F, Dashti, Shervin R

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Herbicides in Ground Water beneath Nebraska's Management Systems Evaluation Area von Spalding, Roy F, Exner, Mary E, Snow, Daniel D, Cassada, David A, Burbach, Mark E, Monson, Stephen J

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Breaking down barriers: The identification of actions to promote gender equality in interdisciplinary marine research institutions von Shellock, Rebecca J., Cvitanovic, Christopher, Mackay, Mary, McKinnon, Merryn C., Blythe, Jessica, Kelly, Rachel, van Putten, Ingrid E., Tuohy, Paris, Bailey, Megan, Begossi, Alpina, Crona, Beatrice, Fakoya, Kafayat A., Ferreira, Beatrice P., Ferrer, Alice J.G., Frangoudes, Katia, Gobin, Judith, Goh, Hong Ching, Haapasaari, Paivi, Hardesty, Britta Denise, Häussermann, Vreni, Hoareau, Kelly, Hornidge, Anna-Katharina, Isaacs, Moenieba, Kraan, Marloes, Li, Yinji, Liu, Min, Lopes, Priscila F.M., Mlakar, Marina, Morrison, Tiffany H., Oxenford, Hazel A., Pecl, Gretta T., Penca, Jerneja, Robinson, Carol, Selim, Samiya, Skern-Mauritzen, Mette, Soejima, Kumi, Soto, Doris, Spalding, Ana K., Vadrot, Alice, Vaidianu, Natașa, Webber, Mona, Wisz, Mary S.

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Inhibition of Protein Kinase Cβ by Enzastaurin Enhances Radiation Cytotoxicity in Pancreatic Cancer von SPALDING, Aaron C, WATSON, Richard, DAVIS, Mary E, KIM, Alex C, LAWRENCE, Theodore S, BEN-JOSEF, Edgar

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