Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors von Spagnuolo, Lauren A, Eltschkner, Sandra, Yu, Weixuan, Daryaee, Fereidoon, Davoodi, Shabnam, Knudson, Susan E, Allen, Eleanor K. H, Merino, Jonathan, Pschibul, Annica, Moree, Ben, Thivalapill, Neil, Truglio, James J, Salafsky, Joshua, Slayden, Richard A, Kisker, Caroline, Tonge, Peter J

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Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity von Cifone, Matthew T., He, YongLe, Basu, Rajeswari, Wang, Nan, Davoodi, Shabnam, Spagnuolo, Lauren A., Si, Yuanyuan, Daryaee, Taraneh, Stivala, Craig E., Walker, Stephen G., Tonge, Peter J.

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An Ordered Water Channel in Staphylococcus aureus FabI: Unraveling the Mechanism of Substrate Recognition and Reduction von Schiebel, Johannes, Chang, Andrew, Merget, Benjamin, Bommineni, Gopal R, Yu, Weixuan, Spagnuolo, Lauren A, Baxter, Michael V, Tareilus, Mona, Tonge, Peter J, Kisker, Caroline, Sotriffer, Christoph A

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Convergent Synthesis of Dendrimers via the Passerini Three-Component Reaction von Jee, Jo-Ann, Spagnuolo, Lauren A, Rudick, Jonathan G

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Alternative Substrate Metabolism in Yarrowia lipolytica von Spagnuolo, Michael, Shabbir Hussain, Murtaza, Gambill, Lauren, Blenner, Mark

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Virologic and immunologic outcomes of treatment with integrase inhibitors in a real-world setting: The RESPOND cohort consortium von Neesgaard, Bastian, Mocroft, Amanda, Zangerle, Robert, Wit, Ferdinand, Lampe, Fiona, Gunthard, Huldrych F., Necsoi, Coca, Law, Matthew, Mussini, Cristina, Castagna, Antonella, Monforte, Antonella d'Arminio, Pradier, Christian, Chkhartisvilli, Nikoloz, Reyes-Uruena, Juliana, Vehreschild, Joerg Janne, Wasmuth, Jan-Christian, Sonnerborg, Anders, Stephan, Christoph, Greenberg, Lauren, Llibre, Josep M., Volny-Anne, Alain, Peters, Lars, Pelchen-Matthews, Annegret, Vannappagari, Vani, Gallant, Joel, Rieger, Armin, Youle, Mike, Braun, Dominique, De Wit, Stephane, Petoumenos, Kathy, Borghi, Vanni, Spagnuolo, Vincenzo, Tsertsvadze, Tengiz, Lundgren, Jens, Ryom, Lene

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Trends in mortality in people with HIV from 1999 to 2020: a multi-cohort collaboration von Tusch, Erich, Ryom, Lene, Pelchen-Matthews, Annegret, Mocroft, Amanda, Elbirt, Daniel, Oprea, Cristiana, Gunthard, Huldrych F, Staehelin, Cornelia, Zangerle, Robert, Suarez, Isabelle, Vehreschild, Jorg Janne, Wit, Ferdinand, Menozzi, Marianna, d'Arminio Monforte, Antonella, Spagnuolo, Vincenzo, Pradier, Christian, Carlander, Christina, Suanzes, Paula, Wasmuth, Jan-Christian, Carr, Andrew, Petoumenos, Kathy, Borgans, Frauke, Bonnet, Fabrice, de Wit, Stephane, El-Sadr, Wafaa, Neesgaard, Bastian, Jaschinski, Nadine, Greenberg, Lauren, Hosein, Sean R, Gallant, Joel, Vannappagari, Vani, Young, Lital, Sabin, Caroline, Lundgren, Jens, Peters, Lars, Reekie, Joanne, Study, D. A. D. Cohort, Study, Respond Cohort

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Clinical Outcomes of 2-Drug Regimens vs 3-Drug Regimens in Antiretroviral Treatment-Experienced People Living With Human Immunodeficiency Virus von Greenberg, Lauren, Ryom, Lene, Neesgaard, Bastian, Wandeler, Gilles, Staub, Therese, Gisinger, Martin, Skoll, Michael, Gunthard, Huldrych F., Scherrer, Alexandra, Mussini, Cristina, Smith, Colette, Johnson, Margaret, De Wit, Stephane, Necsoi, Coca, Pradier, Christian, Wit, Ferdinand, Lehmann, Clara, Monforte, Antonella D'Arminio, Miro, Jose M., Castagna, Antonella, Spagnuolo, Vincenzo, Sonnerborg, Anders, Law, Matthew, Hutchinson, Jolie, Chkhartishvili, Nikoloz, Bolokadze, Natalia, Wasmuth, Jan-Christian, Stephan, Christoph, Vannappagari, Vani, Rogatto, Felipe, Llibre, Josep M., Duvivier, Claudine, Hoy, Jennifer, Bloch, Mark, Bucher, Heiner C., Calmy, Alexandra, Anne, Alain Volny, Pelchen-Matthews, Annegret, Lundgren, Jens D., Peters, Lars, Bansi-Matharu, Loveleen, Mocroft, Amanda

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Trends in mortality in people with HIV from 1999 to 2020: a multi-cohort collaboration von Tusch, Erich, Ryom, Lene, Pelchen-Matthews, Annegret, Mocroft, Amanda, Elbirt, Daniel, Oprea, Cristiana, Günthard, Huldrych F, Staehelin, Cornelia, Zangerle, Robert, Suarez, Isabelle, Vehreschild, Jörg Janne, Wit, Ferdinand, Menozzi, Marianna, d'Arminio Monforte, Antonella, Spagnuolo, Vincenzo, Pradier, Christian, Carlander, Christina, Suanzes, Paula, Wasmuth, Jan-Christian, Carr, Andrew, Petoumenos, Kathy, Borgans, Frauke, Bonnet, Fabrice, De Wit, Stephane, El-Sadr, Wafaa, Neesgaard, Bastian, Jaschinski, Nadine, Greenberg, Lauren, Hosein, Sean R, Gallant, Joel

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Trends in Mortality in People With Human Immunodeficiency Virus From 1999 through 2020: A Multicohort Collaboration von Tusch, E, Ryom, L, Pelchen-Matthews, A, Mocroft, A, Elbirt, D, Oprea, C, Gunthard, HF, Staehelin, C, Zangerle, R, Suarez, I

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Clinical Outcomes of 2-Drug Regimens vs 3-Drug Regimens in Antiretroviral Treatment-Experienced People Living With Human Immunodeficiency Virus von Greenberg, Lauren, Ryom, Lene, Neesgaard, Bastian, Wandeler, Gilles, Staub, Therese, Gisinger, Martin, Skoll, Michael, Gunthard, Huldrych F., Scherrer, Alexandra, Mussini, Cristina, Smith, Colette, Johnson, Margaret, De Wit, Stephane, Necsoi, Coca, Pradier, Christian, Wit, Ferdinand, Lehmann, Clara, Monforte, Antonella D'Arminio, Miro, Jose M., Castagna, Antonella, Spagnuolo, Vincenzo, Sonnerborg, Anders, Law, Matthew, Hutchinson, Jolie, Chkhartishvili, Nikoloz, Bolokadze, Natalia, Wasmuth, Jan-Christian, Stephan, Christoph, Vannappagari, Vani, Rogatto, Felipe, Llibre, Josep M., Duvivier, Claudine, Hoy, Jennifer, Bloch, Mark, Bucher, Heiner C., Calmy, Alexandra, Anne, Alain Volny, Pelchen-Matthews, Annegret, Lundgren, Jens D., Peters, Lars, Bansi-Matharu, Loveleen, Mocroft, Amanda

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Uptake and Discontinuation of Integrase Inhibitors (INSTIs) in a Large Cohort Setting von Greenberg, Lauren, Ryom, Lene, Wandeler, Gilles, Grabmeier-Pfistershammer, Katharina, Öllinger, Angela, Neesgaard, Bastian, Stephan, Christoph, Calmy, Alexandra, Rauch, Andri, Castagna, Antonella, Spagnuolo, Vincenzo, Johnson, Margaret, Stingone, Christof, Mussini, Cristina, De Wit, Stéphane, Necsoi, Coca, Campins, Antoni A., Pradier, Christian, Stecher, Melanie, Wasmuth, Jan-Christian, Monforte, Antonella d'Arminio, Law, Matthew, Puhr, Rainer, Chkhartishvilli, Nikoloz, Tsertsvadze, Tengiz, Garges, Harmony, Thorpe, David, Lundgren, Jens D., Peters, Lars, Bansi-Matharu, Loveleen, Mocroft, Amanda

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Incidence of hypertension in people with HIV who are treated with integrase inhibitors versus other antiretroviral regimens in the RESPOND cohort consortium von Byonanebye, Dathan M., Polizzotto, Mark N., Neesgaard, Bastian, Sarcletti, Mario, Matulionyte, Raimonda, Braun, Dominique L., Castagna, Antonella, Wit, Stéphane, Wit, Ferdinand, Fontas, Eric, Vehreschild, Jörg Janne, Vesterbacka, Jan, Greenberg, Lauren, Hatleberg, Camilla, Garges, Harmony, Gallant, Joel, Volny Anne, Alain, Öllinger, Angela, Mozer‐Lisewska, Iwona, Surial, Bernard, Spagnuolo, Vincenzo, Necsoi, Coca, Valk, Marc, Mocroft, Amanda, Law, Matthew, Ryom, Lene, Petoumenos, Kathy, Hillebregt, M, Rose, N, Hutchinson, J, Zangerle, R, Appoyer, H, Delforge, M, Stephan, C, Bucht, M, Chkhartishvili, N, Chokoshvili, O, Mussini, C, Borghi, V, Pradier, C, Dollet, K, Caissotti, C, Casabona, J, Miro, JM, Smith, C, Lampe, F, Johnson, M, Burns, F, Chaloner, C, Lazzarin, A, Poli, A, Sönnerborg, A, Falconer, K, Svedhem, V, Günthard, H, Ledergerber, B, Bucher, H, Scherrer, A, Wasmuth, JC, Rockstroh, J, Fätkenheuer, G, Stecher, M, Schulze, N, Franke, B, Ryom, Lene, Rooney, J, McNicholl, I, Vannappagari, V, Wandeler, G, Lundgren, J, Kowalska, J, Raben, D, Mocroft, A, Peters, L, Williams, ED, Necsoi, C, D’Arminio Monforte, A, Bruguera, A, Dedes, Nikos, Mendao, Luis, Larsen, JF, Jaschinski, N, Jakobsen, ML, Bruun, T, Bojesen, A, Hansen, EV, Traytel, AK, Elsing, TW, Kristensen, D, Weide, T, Bansi‐Matharu, L, Pelchen‐Matthews, A

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Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration von Tusch, Erich, Ryom, Lene, Pelchen-Matthews, Annegret, Mocroft, Amanda, Elbirt, Daniel, Oprea, Cristiana, Günthard, Huldrych F, Staehelin, Cornelia, Zangerle, Robert, Suarez, Isabelle, Vehreschild, Jörg Janne, Wit, Ferdinand, Menozzi, Marianna, d'Arminio Monforte, Antonella, Spagnuolo, Vincenzo, Pradier, Christian, Carlander, Christina, Suanzes, Paula, Wasmuth, Jan-Christian, Carr, Andrew, Petoumenos, Kathy, Borgans, Frauke, Bonnet, Fabrice, De Wit, Stephane, El-Sadr, Wafaa, Neesgaard, Bastian, Jaschinski, Nadine, Greenberg, Lauren, Hosein, Sean R, Gallant, Joel, Vannappagari, Vani, Young, Lital, Sabin, Caroline, Lundgren, Jens, Peters, Lars, Reekie, Joanne

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Recent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica von Shabbir Hussain, Murtaza, M Rodriguez, Gabriel, Gao, Difeng, Spagnuolo, Michael, Gambill, Lauren, Blenner, Mark

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Clinical Outcomes of 2-Drug Regimens vs 3-Drug Regimens in Antiretroviral Treatment-Experienced People Living With Human Immunodeficiency Virus von Greenberg, Lauren, Ryom, Lene, Neesgaard, Bastian, Wandeler, Gilles, Staub, Therese, Gisinger, Martin, Skoll, Michael, Gunthard, Huldrych F., Scherrer, Alexandra, Mussini, Cristina, Smith, Colette, Johnson, Margaret, De Wit, Stephane, Necsoi, Coca, Pradier, Christian, Wit, Ferdinand, Lehmann, Clara, Monforte, Antonella D'Arminio, Miro, Jose M., Castagna, Antonella, Spagnuolo, Vincenzo, Sonnerborg, Anders, Law, Matthew, Hutchinson, Jolie, Chkhartishvili, Nikoloz, Bolokadze, Natalia, Wasmuth, Jan-Christian, Stephan, Christoph, Vannappagari, Vani, Rogatto, Felipe, Llibre, Josep M., Duvivier, Claudine, Hoy, Jennifer, Bloch, Mark, Bucher, Heiner C., Calmy, Alexandra, Anne, Alain Volny, Pelchen-Matthews, Annegret, Lundgren, Jens D., Peters, Lars, Bansi-Matharu, Loveleen, Mocroft, Amanda

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A [32P]NAD+-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors von Yu, Weixuan, Neckles, Carla, Chang, Andrew, Bommineni, Gopal Reddy, Spagnuolo, Lauren, Zhang, Zhuo, Liu, Nina, Lai, Christina, Truglio, James, Tonge, Peter J.

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Rational Optimization of Diphenyl Ether Binding Kinetics to the Enoyl-ACP Reductase FabI1 from Burkholderia pseudomallei von Neckles, Carla, Eltschkner, Sandra, Cummings, Jason E., Hirschbeck, Maria, Daryaee, Fereidoon, Bommineni, Gopal R., Zhang, Zhuo, Spagnuolo, Lauren, Yu, Weixuan, Davoodi, Shabnam, Slayden, Richard A., Kisker, Caroline, Tonge, Peter J.

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Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase von Neckles, Carla, Eltschkner, Sandra, Cummings, Jason E, Hirschbeck, Maria, Daryaee, Fereidoon, Bommineni, Gopal R, Zhang, Zhuo, Spagnuolo, Lauren, Yu, Weixuan, Davoodi, Shabnam, Slayden, Richard A, Kisker, Caroline, Tonge, Peter J

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A [32P]-NAD+-based method to identify and quantitate long residence time enoyl-ACP reductase inhibitors von Yu, Weixuan, Neckles, Carla, Chang, Andrew, Bommineni, Gopal Reddy, Spagnuolo, Lauren, Zhang, Zhuo, Liu, Nina, Lai, Christina, Truglio, James, Tonge, Peter J.

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