Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase‑1 (IDO1) von White, Catherine, McGowan, Meredeth A, Zhou, Hua, Sciammetta, Nunzio, Fradera, Xavier, Lim, Jongwon, Joshi, Elizabeth M, Andrews, Christine, Nickbarg, Elliott B, Cowley, Phillip, Trewick, Sarah, Augustin, Martin, von Köenig, Konstanze, Lesburg, Charles A, Otte, Karin, Knemeyer, Ian, Woo, Hyun, Yu, Wensheng, Cheng, Mangeng, Spacciapoli, Peter, Geda, Prasanthi, Song, Xuelei, Smotrov, Nadya, Curran, Patrick, Heo, Mee Ra, Abeywickrema, Pravien, Miller, J. Richard, Bennett, David Jonathan, Han, Yongxin

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Anticandida Activity Is Retained in P-113, a 12-Amino-Acid Fragment of Histatin 5 von ROTHSTEIN, David M, SPACCIAPOLI, Peter, TRAN, Linh T, TAO XU, ROBERTS, F. Donald, DALLA SERRA, Mauro, BUXTON, Deborah K, OPPENHEIM, Frank G, FRIDEN, Phillip

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A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit von Kopinja, Johnny, Sevilla, Raquel S., Levitan, Diane, Dai, David, Vanko, Amy, Spooner, Edward, Ware, Chris, Forget, Robert, Hu, Kun, Kral, Astrid, Spacciapoli, Peter, Kennan, Richard, Jayaraman, Lata, Pucci, Vincenzo, Perera, Samanthi, Zhang, Weisheng, Fischer, Christian, Lam, Michael H.

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Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology von Lu, Min, Zhang, Hongjun, Li, Derun, Childers, Matthew, Pu, Qinglin, Palte, Rachel L, Gathiaka, Symon, Lyons, Thomas W, Palani, Anandan, Fan, Peter W, Spacciapoli, Peter, Miller, J. Richard, Cho, Hyelim, Cheng, Mangeng, Chakravarthy, Kalyan, O’Neil, Jennifer, Eangoor, Padmanabhan, Beard, Adam, Kim, Hai-Young, Saurí, Josep, Gunaydin, Hakan, Sloman, David L, Siliphaivanh, Phieng, Cumming, Jared, Fischer, Christian

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Discovery of 1‑(1H‑Pyrazolo[4,3‑c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers von Lim, Jongwon, Kelley, Elizabeth H, Methot, Joey L, Zhou, Hua, Petrocchi, Alessia, Chen, Hongmin, Hill, Susan E, Hinton, Marlene C, Hruza, Alan, Jung, Joon O, Maclean, John K. F, Mansueto, My, Naumov, George N, Philippar, Ulrike, Raut, Shruti, Spacciapoli, Peter, Sun, Dongyu, Siliphaivanh, Phieng

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Biochemical Characterization of Heterodimeric Isocitrate Dehydrogenase I Using a Novel High‐throughput Mass Spectrometry‐based Assay von Piesvaux, Jennifer, Miller, Richard, McCoy, Mark, Hou, Yan, Spacciapoli, Peter, Fischer, Christian, Machacek, Michelle, Fradera, Xavier

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Carbamate and N‑Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors von Li, Derun, Deng, Yongqi, Achab, Abdelghani, Bharathan, Indu, Hopkins, Brett Andrew, Yu, Wensheng, Zhang, Hongjun, Sanyal, Sulagna, Pu, Qinglin, Zhou, Hua, Liu, Kun, Lim, Jongwon, Fradera, Xavier, Lesburg, Charles A, Lammens, Alfred, Martinot, Theodore A, Cohen, Ryan D, Doty, Amy C, Ferguson, Heidi, Nickbarg, Elliott B, Cheng, Mangeng, Spacciapoli, Peter, Geda, Prasanthi, Song, Xuelei, Smotrov, Nadya, Abeywickrema, Pravien, Andrews, Christine, Chamberlin, Chad, Mabrouk, Omar, Curran, Patrick, Richards, Matthew, Saradjian, Peter, Miller, J. Richard, Knemeyer, Ian, Otte, Karin M, Vincent, Stella, Sciammetta, Nunzio, Pasternak, Alexander, Bennett, David Jonathan, Han, Yongxin

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Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors von Li, Derun, Zhang, Hongjun, Lyons, Thomas W, Lu, Min, Achab, Abdelghani, Pu, Qinglin, Childers, Matthew, Mitcheltree, Matthew J, Wang, Jialiang, Martinot, Theodore A, McMinn, Spencer E, Sloman, David L, Palani, Anandan, Beard, Adam, Nogle, Lisa, Gathiaka, Symon, Saurí, Josep, Kim, Hai-Young, Adpressa, Donovon, Spacciapoli, Peter, Miller, J. Richard, Palte, Rachel L, Lesburg, Charles A, Cumming, Jared, Fischer, Christian

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Conformation constraint of anilides enabling the discovery of tricyclic lactams as potent MK2 non-ATP competitive inhibitors von Xiao, Dong, Palani, Anandan, Huang, Xianhai, Sofolarides, Michael, Zhou, Wei, Chen, Xiao, Aslanian, Robert, Guo, Zhuyan, Fossetta, James, Tian, Fang, Trivedi, Prashant, Spacciapoli, Peter, Whitehurst, Charles E., Lundell, Daniel

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Antimicrobial activity of silver nitrate against periodontal pathogens von Spacciapoli, Peter, Buxton, Debra, Rothstein, David, Friden, Phillip

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Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors von Huang, Xiaohua, Shipps, Gerald W., Cheng, Cliff C., Spacciapoli, Peter, Zhang, Xingmin, McCoy, Mark A., Wyss, Daniel F., Yang, Xianshu, Achab, Abdelghani, Soucy, Kyle, Montavon, Donna K., Murphy, Denise M., Whitehurst, Charles E.

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DNA polymerase III of Mycoplasma pulmonis: isolation and characterization of the enzyme and its structural gene, polC von Barnes, Marjorie H., Tarantino, Paul M., Spacciapoli, Peter, Brown, Neal C., Yu, Huilan, Dybvig, Kevin

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Discovery and Characterization of Orthosteric and Allosteric Muscarinic M2 Acetylcholine Receptor Ligands by Affinity Selection–Mass Spectrometry von Whitehurst, Charles E., Nazef, Naim, Annis, D. Allen, Hou, Yongmin, Murphy, Denise M., Spacciapoli, Peter, Yao, Zhiping, Ziebell, Michael R., Cheng, Cliff C., Shipps, Jr, Gerald W., Felsch, Jason S., Lau, David, Nash, Huw M.

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Sustained release of silver from periodontal wafers for treatment of periodontitis von Bromberg, Lev E, Braman, Virginia M, Rothstein, David M, Spacciapoli, Peter, O’Connor, Sandra M, Nelson, Eric J, Buxton, Debra K, Tonetti, Maurizio S, Friden, Phillip M

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Histatin-derived peptides: potential agents to treat localised infections von Rothstein, David M, Friden, Phillip, Spacciapoli, Peter, Oppenheim, Frank G, Helmerhorst, Eva J

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The 3′–5′ exonuclease site of DNA polymerase III from Gram-positive bacteria: definition of a novel motif structure von Barnes, Marjorie H., Spacciapoli, Peter, Li, Dong Hui, Brown, Neal C.

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Structural and catalytic properties of copper in lysyl oxidase von Gacheru, S.N., Trackman, P.C., Shah, M.A., O'Gara, C.Y., Spacciapoli, P, Greenaway, F.T., Kagan, H.M.

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[43] Purification of bacteriophage T4 DNA replication proteins von Nossal, Nancy G., Hinton, Deborah M., Hobbs, Lisa J., Spacciapoli, Peter

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Purines in tRNAs required for recognition by ATP/CTP:tRNA nucleotidyltransferase from rabbit liver von Spacciapoli, Peter, Thurlow, David L.

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ANTIFUNGALE UND ANTIBAKTERIELLE PEPTIDE von ROBERTS, DONALD, SPACCIAPOLI, PETER, OPPENHEIM, G, FRIDEN, M, XU, TAO

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