A phase I/II feasibility study of cetuximab with 5FU and mitomycin C or cisplatin with concurrent radiotherapy in muscle invasive bladder cancer von James, Nicholas D., Pirrie, Sarah, Liu, Wenyu, Ford, Daniel, Zarkar, Anjali, Southgate, Elizabeth, Desai, Amisha, Hussain, Syed A.

Volltext

SMALL: Open surgery versus minimally invasive vacuum-assisted excision for small screen-detected breast cancer—A UK phase III randomised multi-centre trial von McIntosh, Stuart, Coles, Charlotte E., Dodwell, David John, Elder, Kenneth, Foster, Jessica, Gaunt, Claire, Kirkham, Amanda, Lyburn, Iain, Morgan, Jenna, Paramasivan, Sangeetha, Pinder, Sarah E., Pirrie, Sarah, Potter, Shelley, Roberts, Tracy, Sharma, Nisha, Stobart, Hilary, Southgate, Elizabeth, Taylor-Phillips, Sian, Wallis, Matthew, Rea, Daniel William

Volltext

TUXEDO: a phase I/II trial of cetuximab with chemoradiotherapy in muscle‐invasive bladder cancer von James, Nicholas D., Liu, Wenyu, Pirrie, Sarah, Kaur, Baljit, Hendron, Carey, Ford, Daniel, Zarkar, Anjali, Viney, Richard, Southgate, Elizabeth, Desai, Amisha, Hussain, Syed A., Barber, Jim, Syndikus, Isabel, Malik, Zafar, Eswar, Chinnamani, Mangar, Stephen, Money‐Kyrle, Julian, Lydon, Anna, Van Der Voet, Johannes, James, Nicholas, Zarkar, Anjali, Ford, Dan

Volltext

SMALL: Open surgery versus minimally invasive vacuum-assisted excision for small screen-detected breast cancers von McIntosh, Stuart, Coles, Charlotte E., Conefrey, Carmel, Dodwell, David John, Foster, Jessica, Gaunt, Claire, Kirkham, Amanda, Lyburn, Iain, Morgan, Jenna, Paramasivan, Sangeetha, Pinder, Sarah E., Pirrie, Sarah, Potter, Shelley, Roberts, Tracy, Sharma, Nisha, Stobart, Hilary, Southgate, Elizabeth, Taylor-Phillips, Sian, Wallis, Matthew, Rea, Dan

Volltext

Abstract OT1-06-02: SMALL - Open surgery versus minimally invasive vacuum-assisted excision for small screen detected breast cancer: A phase 3 randomised trial von McIntosh, Stuart A, Coles, Charlotte E, Conefrey, Carmel, Dodwell, David, Elder, Kenneth, Foster, Jessica, Gaunt, Claire, Kirkham, Amanda, Lyburn, Iain, Morgan, Jenna, Paramasivan, Sangeetha, Pinder, Sarah, Pirrie, Sarah, Potter, Shelley, Roberts, Tracy, Sharma, Nisha, Stobart, Hilary, Southgate, Elizabeth, Taylor-Phillips, Sian, Wallis, Matthew, Rea, Daniel

Volltext

Phase I/II trial of cetuximab with 5-fluorouracil and mitomycin C concurrent with radiotherapy in patients with muscle invasive bladder cancer von Hussain, Syed A., Buckley, Laura, Kaur, Baljit, Hendron, Carey, Zarkar, Anjali, Ford, Daniel, Viney, Richard, Syndikus, Isabel, Malik, Zafar, Eswar, Chinnamani, Desai, Amisha, Southgate, Elizabeth, Mangar, Stephen, Van Der Voet, Johannes, Lydon, Anna, James, Nicholas D.

Volltext

Abstract OT3-20-02: SMALL: Open Surgery versus Minimally invasive vacuum-Assisted excision for smaLL screen-detected breast cancer – a UK phase III randomised multi-centre trial von McIntosh, Stuart A., Coles, Charlotte E., Dodwell, David, Elder, Kenneth, Foster, Jessica, Gaunt, Claire, Kirkham, Amanda, Lyburn, Iain, Morgan, Jenna, Paramasivan, Sangeetha, Pinder, Sarah E., Pirrie, Sarah, Potter, Shelley, Roberts, Tracy, Sharma, Nisha, Stobart, Hilary, Southgate, Elizabeth, Taylor-Phillips, Sian, Wallis, Matthew, Rea, Daniel

Volltext

Abstract P6-05-17: Recruitment challenges in a UK surgical de-escalation study: preliminary qualitative research findings from the SMALL trial von McIntosh, Stuart A., Coles, Charlotte E., Dodwell, David, Elder, Kenneth, Foster, Jessica, Gaunt, Claire, Kirkham, Amanda, Lyburn, Iain, Morgan, Jenna, Pinder, Sarah E., Pirrie, Sarah, Potter, Shelley, Roberts, Tracy, Sharma, Nisha, Stobart, Hilary, Southgate, Elizabeth, Taylor-Phillips, Sian, Wallis, Matthew, Rea, Daniel, Paramasivan, Sangeetha

Volltext

Radiotherapy skin care: A survey of practice in the UK von Harris, Rachel, Probst, Heidi, Beardmore, Charlotte, James, Sarah, Dumbleton, Claire, Bolderston, Amanda, Faithfull, Sara, Wells, Mary, Southgate, Elizabeth

Volltext

Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease von Stephens, Jonathan, Dewhurst, Eleanor, Malka, Samantha, Plagnol, Vincent, Rizzo, Roberta, Scott, Richard H., Henderson, Robert H.H., MacLaren, Robert E., Paterson, Joan, Aitman, Timothy, Ali, Sonia, Ambegaonkar, Gautum, Arno, Gavin, Astle, William, Attwood, Antony, Bennett, David, Bitner-Glindzicz, Maria, Bleda, Marta, Boggard, Harm, Carss, Keren, Clements-Brod, Naomi, DaCosta, Rosa, De Vries, Minka, Dewhurst, Eleanor, Drewe, Elizabeth, Egner, William, Erber, Wendy N., Everington, Tamara, Fletcher, Debra, Freson, Kathleen, Gale, Daniel, Ghali, Neeti, Ghurye, Rohit, Gräf, Stefan, Greene, Daniel, Grigoriadou, Sofia, Grozeva, Detelina, Hackett, Scott, Hadinnapola, Charaka, Hague, Rosie, Hammerton, Tracey, Heemskerk, Johan W.M., Holder, Muriel, Holder, Susan, Huissoon, Aarnoud, Hurst, Jane, Jolles, Stephen, Keeling, David, Kennedy, Fiona, Kiely, David, Lawrie, Allan, Lear, Sara, Lees, Melissa, Lentaigne, Claire, Lorenzo, Lorena, Mangles, Sarah, Mapeta, Rutendo, Masati, Larahmie, Mathias, Mary, Michaelides, Michel, Millar, Carolyn M., Moledina, Shahin, Moore, Anthony, Murng, Sai, Oksenhendler, Eric, Park, Soo-Mi, Patch, Chris, Paterson, Joan, Penkett, Christopher J., Pepke-Zaba, Joanna, Pollock, Val, Qasim, Waseem, Quinti, Isabella, Reid, Evan, Rondina, Matthew, Rosser, Elisabeth, Santra, Saikat, Sargur, Ravishankar, Savic, Sinisa, Scully, Marie, Sewell, Carrock, Smith, Kenneth, Southgate, Laura, Stauss, Hans, Stein, Penelope, Talks, Kate, Thomas, Ellen, Thrasher, Adrian, Tischkowitz, Marc, Titterton, Catherine, Turro, Ernest, von Ziegenweldt, Julie, Vonk Noordegraaf, Anton, Wakeling, Emma, Wanjiku, Ivy, Welch, Steve, Westbury, Sarah, Woods, Geoffrey, Yong, Patrick, Webster, Andrew R.

Volltext

SARS-CoV-2 evolution during treatment of chronic infection von Kemp, Steven A., Collier, Dami A., Datir, Rawlings P., Ferreira, Isabella A. T. M., Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J., Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E., Briggs, John A. G., van Gils, Marit J., Smith, Kenneth G. C., Bradley, John R., Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D., Goldstein, Richard A., Smielewska, Anna, Skittrall, Jordan P., Gouliouris, Theodore, Goodfellow, Ian G., Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J. R., McCoy, Laura E., Gupta, Ravindra K.

Volltext

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity von Shepherd, James, Koshy, Cherian, Wise, Emma, Curran, Tanya, Adams, Helen, Moore, Catrin, Khokhar, Fahad A., Reynolds, Nicola, Afifi, Safiah, Price, Anna, Kitchen, Christine, Merrick, Ian, Connor, Thomas R., Bresner, Catherine, Robson, Samuel C., Menegazzo, Mirko, Clark, Gemma, Fleming, Vicki M., Howson-Wells, Hannah C., Bird, Paul, Helmer, Thomas, Fallon, Karlie, du Plessis, Louis, Attwood, Stephen, Vasylyeva, Tetyana, Chaudhry, Yasmin, Moses, Samuel, Ryan, Felicity, Brown, Julianne Rose, Lee, Jack C.D., Alcolea-Medina, Adela, Moore, Nathan, Cortes, Nicholas, Williams, Rebecca, Smith, Darren L., Holmes, Alison, Price, James, Rowan, Aileen, Taylor, Graham P., Watts, Joanne, Ludden, Catherine, George, Ryan P., Li, Kathy K., Carmichael, Stephen N., Johnson, Natasha, Orton, Richard J., Hale, Antony D., Harper, Katherine L., Eltringham, Gary, Coupland, Lindsay J., Barton, Edward, Scott, Garren, Yew, Wen C., Resende Silva, Paola C., Justice, Anita, Chand, Meera, Williams, David, Harrison, Ian, Chalker, Vicki, Heyburn, David, Downing, Fatima, Watkins, Joanne, Howe, Robin, Taylor, Sarah, Wain, John, Rudder, Steven, Gilroy, Rachel A.J., Alikhan, Nabil-Fareed, Casey, Anna, Liggett, Steven, Caller, Laura G., Panchbhaya, Yasmin N., Forrest, Leysa M., Findlay, Jacqueline, Beggs, Andrew, Hesketh, Andrew R., Higginson, Ellen E., Aggarwal, Dinesh, Colquhoun, Rachel, Ashworth, Jordan, McCrone, J.T., Michell, Stephen L., Hughes, Margaret, Rainbow, Lucille, Haldenby, Sam T., Green, Luke R., Parker, Matthew D., Bridgewater, Hannah E., Alam, Mohammad T., Quail, Mike, Thurston, Scott, Beaver, Charlotte, McMinn, Liz, Puethe, Christoph, Tonkin-Hill, Gerry, Smith, Christen, Jamrozy, Dorota, Patel, Minal, Drury, Eleanor, Loman, Nicholas J.

Volltext

Genomic reconstruction of the SARS-CoV-2 epidemic in England von Vöhringer, Harald S., Sanderson, Theo, Sinnott, Matthew, De Maio, Nicola, Nguyen, Thuy, Goater, Richard, Schwach, Frank, Harrison, Ian, Hellewell, Joel, Ariani, Cristina V., Gonçalves, Sonia, Jackson, David K., Johnston, Ian, Jung, Alexander W., Saint, Callum, Sillitoe, John, Suciu, Maria, Goldman, Nick, Panovska-Griffiths, Jasmina, Birney, Ewan, Volz, Erik, Funk, Sebastian, Kwiatkowski, Dominic, Chand, Meera, Martincorena, Inigo, Barrett, Jeffrey C., Gerstung, Moritz

Volltext

Deoxynybomycins inhibit mutant DNA gyrase and rescue mice infected with fluoroquinolone-resistant bacteria von Parkinson, Elizabeth I., Bair, Joseph S., Nakamura, Bradley A., Lee, Hyang Y., Kuttab, Hani I., Southgate, Emma H., Lezmi, Stéphane, Lau, Gee W., Hergenrother, Paul J.

Volltext

Elucidating the genetic architecture of Adams–Oliver syndrome in a large European cohort von Meester, Josephina A.N., Sukalo, Maja, Schröder, Kim C., Schanze, Denny, Baynam, Gareth, Borck, Guntram, Bramswig, Nuria C., Duman, Duygu, Gilbert‐Dussardier, Brigitte, Holder‐Espinasse, Muriel, Itin, Peter, Johnson, Diana S., Joss, Shelagh, Koillinen, Hannele, McKenzie, Fiona, Morton, Jenny, Nelle, Heike, Reardon, Willie, Roll, Claudia, Salih, Mustafa A., Savarirayan, Ravi, Scurr, Ingrid, Splitt, Miranda, Thompson, Elizabeth, Titheradge, Hannah, Travers, Colm P., Maldergem, Lionel, Whiteford, Margo, Wieczorek, Dagmar, Vandeweyer, Geert, Trembath, Richard, Laer, Lut, Loeys, Bart L., Zenker, Martin, Southgate, Laura, Wuyts, Wim

Volltext

Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data von Farmery, James H. R., Smith, Mike L., Lynch, Andy G.

Volltext

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension von Hadinnapola, Charaka, Bleda, Marta, Haimel, Matthias, Screaton, Nicholas, Swift, Andrew, Dorfmüller, Peter, Preston, Stephen D, Southwood, Mark, Hernandez-Sanchez, Jules, Martin, Jennifer, Treacy, Carmen, Yates, Katherine, Bogaard, Harm, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A, Gibbs, Simon, Girerd, Barbara, Holden, Simon, Humbert, Marc, Kiely, David G, Lawrie, Allan, Machado, Rajiv, MacKenzie Ross, Robert, Moledina, Shahin, Montani, David, Newnham, Michael, Peacock, Andrew, Pepke-Zaba, Joanna, Rayner-Matthews, Paula, Shamardina, Olga, Soubrier, Florent, Southgate, Laura, Suntharalingam, Jay, Toshner, Mark, Trembath, Richard, Vonk Noordegraaf, Anton, Wilkins, Martin R, Wort, Stephen J, Wharton, John, Gräf, Stefan, Morrell, Nicholas W

Volltext

Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes von West, Hannah, Carss, Keren, Shakeel, Hassan, Adlard, Julian, Cole, Trevor, Kwong, Ava, Paterson, Joan, Searle, Claire, Skytte, Anne-Bine, Aitman, Timothy, Ambegaonkar, Gautum, Antrobus, Richard, Arno, Gavin, Astle, William, Attwood, Antony, Austin, Steve, Bakchoul, Tamam, Bennett, David, Bitner-Glindzicz, Maria, Bleda, Marta, Bolton-Maggs, Paula, Booth, Claire, Clements-Brod, Naomi, Clowes, Virginia, Collins, Peter, Cookson, Victoria, Creaser-Myers, Amanda, DaCosta, Rosa, Davies, Sophie, Deegan, Patrick, Dewhurst, Eleanor, Doffinger, Rainer, Drewe, Elizabeth, Favier, Remi, Firth, Helen, Furie, Bruce, Furnell, Abigail, Gardham, Alice, Gissen, Paul, Gomez, Keith, Graf, Stefan, Gräf, Stefan, Greenhalgh, Alan, Hackett, Scott, Haimel, Matthias, Herwadkar, Archana, Holder, Muriel, Huissoon, Aarnoud, James, Roger, Kennedy, Fiona, Kingston, Nathalie, Kuijpers, Taco, Lawrie, Allan, Lentaigne, Claire, Machado, Rajiv, Maher, Eamonn, Mangles, Sarah, Manson, Ania, Matser, Vera, McDermott, Elizabeth, Megy, Karyn, Millar, Carolyn M., Morrell, Nicholas, Ouwehand, Willem H., Papadia, Sofia, Payne, Jeanette, Peacock, Andrew, Pollock, Val, Quinti, Isabella, Rayner-Matthews, Paula, Rehnstrom, Karola, Rhodes, Christopher J., Richardson, Sylvia, Richter, Alex, Rondina, Matthew, Rosser, Elisabeth, Rue-Albrecht, Kevin, Sargur, Ravishankar, Savic, Sinisa, Schotte, Gwen, Schulze, Harald, Seneviratne, Suranjith, Shamardina, Olga, Simeoni, Ilenia, Staines, Simon, Stark, Hannah, Stock, Sophie, Thaventhiran, James, Thompson, Dorothy, Toh, Cheng-Hock, Turek, Wojciech, Wassmer, Evangeline, Watt, Christopher, Wharton, John, Williamson, Catherine, Woods, Geoff, Wort, John, Yeatman, Nigel, Tischkowitz, Marc D., Maher, Eamonn R.

Volltext

A Rare Urachal Cyst in a Case of Ketamine-induced Cystitis Provides Mechanistic Insights von Kidger, Elizabeth, Stahlschmidt, Jens, Garthwaite, Mary, Fulford, Simon, Southgate, Jennifer, Baker, Simon C

Volltext

De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures von Duarte, Sofia T., Charles, Perinne, Pfundt, Rolph, van Bokhoven, Hans, van Ravenswaaij-Arts, Conny, Morrell, Nicholas W., Thrasher, Adrian, Fletcher, Debra, Veltman, Marijke, Davis, John, Frary, Amy, Martin, Jennifer M., Collins, Janine, Favier, Remi, Hart, Daniel, Heemskerk, Johan W.M., Liesner, Ri, Mangles, Sarah, Roughley, Catherine, Tait, R. Campbell, Thachil, Jecko, Van Geet, Chris, De Vries, Minka, Warner, Timothy Q., Furnell, Abigail, Mapeta, Rutendo, Whitehorn, Deborah, Daugherty, Louise, Deevi, Sri V.V., Hu, Fengyuan, Matser, Vera, Megy, Karyn, Tuna, Salih, von Ziegenweldt, Julie, Haimel, Matthias, Richardson, Sylvia, Rankin, Stuart, Anderson, Julie, Stock, Sophie, Armstrong, Ruth, Bitner-Glindzicz, Maria, Brady, Angie, Clement, Emma, Firth, Helen, Flinter, Frances, French, Courtney, Holder, Muriel, Hurst, Jane, Josifova, Dragana, Krishnakumar, Deepa, Kurian, Manju A., Mehta, Sarju, Moore, Anthony, Rankin, Julia, Reid, Evan, Scott, Richard, Thomas, Ellen, Wassmer, Evangeline, Creaser-Myers, Amanda, Gall, Henning, Ghataorhe, Pavandeep K., Houweling, Arjan C., in’t Veld, Anna Huis, Ross, Rob V. Mackenzie, Rhodes, Christopher J., Soubrier, Florent, Treacy, Carmen M., Vonk Noordegraaf, Anton, Antrobus, Richard, Arumugakani, Gururaj, Bibi, Shahnaz, Devlin, Lisa, Ghurye, Rohit, Grigoriadou, Sofia, Harper, Lorraine, Herwadkar, Archana, Jolles, Stephen, Kumararatne, Dinakantha, Lorenzo, Lorena, Murng, Sai, Nejentsev, Sergey, Quinti, Isabella, Samarghitean, Crina, Savic, Sinisa, Yong, Patrick, Ancliff, Phil, Layton, Mark, Mead, Adam, Roy, Noémi, Chambers, Jenny, Estiu, Cecelia, Simpson, Michael, Emmerson, Ingrid, McCarthy, Mark, Van Zuydam, Natalie, Afzal, Maryam, Colby, Elizabeth, Boycott, Kym M., Majewski, Jacek, Dyment, David

Volltext