The biosynthesis of nikkomycin X from histidine in Streptomyces tendae von Evans, Delwyn R., Herbert, Richard B., Baumberg, Simon, Cove, Jonathan H., Southey, Elizabeth A., Buss, Antony D., Dawson, Michael J., Noble, David, Rudd, Brian A.M.

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PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival von Rosty, Christophe, Young, Joanne P, Walsh, Michael D, Clendenning, Mark, Sanderson, Kristy, Walters, Rhiannon J, Parry, Susan, Jenkins, Mark A, Win, Aung Ko, Southey, Melissa C, Hopper, John L, Giles, Graham G, Williamson, Elizabeth J, English, Dallas R, Buchanan, Daniel D

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SAM-DNMT3A, a strategy for induction of genome-wide DNA methylation, identifies DNA methylation as a vulnerability in ER-positive breast cancers von Hosseinpour, Mahnaz, Xi, Xinqi, Liu, Ling, Malaver-Ortega, Luis, Perlaza-Jimenez, Laura, Joo, Jihoon E., York, Harrison M., Beesley, Jonathan, Caldon, C. Elizabeth, Dugué, Pierre-Antoine, Dowty, James G., Arumugam, Senthil, Southey, Melissa C., Rosenbluh, Joseph

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Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype von Jayasekara, Harindra, English, Dallas R., Haydon, Andrew, Hodge, Allison M., Lynch, Brigid M., Rosty, Christophe, Williamson, Elizabeth J., Clendenning, Mark, Southey, Melissa C., Jenkins, Mark A., Room, Robin, Hopper, John L., Milne, Roger L., Buchanan, Daniel D., Giles, Graham G., MacInnis, Robert J.

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Australian genome-wide association study confirms higher female risk for adult glioma associated with variants in the region of CCDC26 von Alpen, Karen, Vajdic, Claire M, MacInnis, Robert J, Milne, Roger L, Koh, Eng-Siew, Hovey, Elizabeth, Harrup, Rosemary, Bruinsma, Fiona, Nguyen, Tuong L, Li, Shuai, Joseph, David, Benke, Geza, Dugué, Pierre-Antoine, Southey, Melissa C, Giles, Graham G, Rosenthal, Mark, Drummond, Katharine J, Nowak, Anna K, Hopper, John L, Kapuscinski, Miroslaw, Makalic, Enes

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Heritable DNA methylation marks associated with susceptibility to breast cancer von Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C.

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Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis von HUGHES, Laura Ae, WILLIAMSON, Elizabeth J, DEN BRANDT, Piet A.van, GOLDBOHM, R. Alexandra, WEIJENBERG, Matty P, ENGLISH, Dallas R, ENGELAND, Manon Van, JENKINS, Mark A, GILES, Graham G, HOPPER, John L, SOUTHEY, Melissa C, YOUNG, Joanne P, BUCHANAN, Daniel D, WALSH, Michael D

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Should the grading of colorectal adenocarcinoma include microsatellite instability status? von Rosty, Christophe, MD, PhD FRCPA, Williamson, Elizabeth J., PhD, Clendenning, Mark, PhD, Walters, Rhiannon J., BAppSc, Win, Aung K., MBBS, MPH, Jenkins, Mark A., PhD, Hopper, John L., PhD, Winship, Ingrid M., MD, FRACP, Southey, Melissa C., PhD, Giles, Graham G., PhD, English, Dallas R., PhD, Buchanan, Daniel D., PhD

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Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever von Southey, Elizabeth R., Soares-Weiser, Karla, Kleijnen, Jos

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Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects von Howe, Laurence J., Nivard, Michel G., Morris, Tim T., Hansen, Ailin F., Rasheed, Humaira, Cho, Yoonsu, Chittoor, Geetha, Ahlskog, Rafael, Lind, Penelope A., Palviainen, Teemu, van der Zee, Matthijs D., Cheesman, Rosa, Mangino, Massimo, Wang, Yunzhang, Li, Shuai, Klaric, Lucija, Ratliff, Scott M., Bielak, Lawrence F., Nygaard, Marianne, Giannelis, Alexandros, Willoughby, Emily A., Reynolds, Chandra A., Balbona, Jared V., Andreassen, Ole A., Ask, Helga, Baras, Aris, Bauer, Christopher R., Boomsma, Dorret I., Campbell, Archie, Campbell, Harry, Chen, Zhengming, Christofidou, Paraskevi, Corfield, Elizabeth, Dahm, Christina C., Dokuru, Deepika R., Evans, Luke M., de Geus, Eco J. C., Giddaluru, Sudheer, Gordon, Scott D., Harden, K. Paige, Hill, W. David, Hughes, Amanda, Kerr, Shona M., Kim, Yongkang, Kweon, Hyeokmoon, Latvala, Antti, Lawlor, Deborah A., Li, Liming, Lin, Kuang, Magnus, Per, Magnusson, Patrik K. E., Mallard, Travis T., Martikainen, Pekka, Mills, Melinda C., Njølstad, Pål Rasmus, Overton, John D., Pedersen, Nancy L., Porteous, David J., Reid, Jeffrey, Silventoinen, Karri, Southey, Melissa C., Stoltenberg, Camilla, Tucker-Drob, Elliot M., Wright, Margaret J., Hewitt, John K., Keller, Matthew C., Stallings, Michael C., Lee, James J., Christensen, Kaare, Kardia, Sharon L. R., Peyser, Patricia A., Smith, Jennifer A., Wilson, James F., Hopper, John L., Hägg, Sara, Spector, Tim D., Pingault, Jean-Baptiste, Plomin, Robert, Havdahl, Alexandra, Bartels, Meike, Martin, Nicholas G., Oskarsson, Sven, Justice, Anne E., Millwood, Iona Y., Hveem, Kristian, Naess, Øyvind, Willer, Cristen J., Åsvold, Bjørn Olav, Koellinger, Philipp D., Kaprio, Jaakko, Medland, Sarah E., Walters, Robin G., Benjamin, Daniel J., Turley, Patrick, Evans, David M., Davey Smith, George, Hayward, Caroline, Brumpton, Ben, Hemani, Gibran, Davies, Neil M.

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Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features von Rosty, Christophe, Young, Joanne P, Walsh, Michael D, Clendenning, Mark, Walters, Rhiannon J, Pearson, Sally, Pavluk, Erika, Nagler, Belinda, Pakenas, David, Jass, Jeremy R, Jenkins, Mark A, Win, Aung Ko, Southey, Melissa C, Parry, Susan, Hopper, John L, Giles, Graham G, Williamson, Elizabeth, English, Dallas R, Buchanan, Daniel D

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Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classi... von de la Hoya, Miguel, Soukarieh, Omar, López-Perolio, Irene, Vega, Ana, Walker, Logan C, van Ierland, Yvette, Baralle, Diana, Santamariña, Marta, Lattimore, Vanessa, Wijnen, Juul, Whiley, Philip, Blanco, Ana, Raponi, Michela, Hauke, Jan, Wappenschmidt, Barbara, Becker, Alexandra, Hansen, Thomas V O, Behar, Raquel, Investigators, KConFaB, Niederacher, Diether, Arnold, Norbert, Dworniczak, Bernd, Steinemann, Doris, Faust, Ulrike, Rubinstein, Wendy, Hulick, Peter J, Houdayer, Claude, Caputo, Sandrine M, Castera, Laurent, Pesaran, Tina, Chao, Elizabeth, Brewer, Carole, Southey, Melissa C, van Asperen, Christi J, Singer, Christian F, Sullivan, Jan, Poplawski, Nicola, Mai, Phuong, Peto, Julian, Johnson, Nichola, Burwinkel, Barbara, Surowy, Harald, Bojesen, Stig E, Flyger, Henrik, Lindblom, Annika, Margolin, Sara, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Galastri, Laura, Olson, Janet E, Hallberg, Emily, Giles, Graham G, Milne, Roger L, Andrulis, Irene L, Glendon, Gord, Hall, Per, Czene, Kamila, Blows, Fiona, Shah, Mitul, Wang, Qin, Dennis, Joe, Michailidou, Kyriaki, McGuffog, Lesley, Bolla, Manjeet K, Antoniou, Antonis C, Easton, Douglas F, Couch, Fergus J, Tavtigian, Sean, Vreeswijk, Maaike P, Parsons, Michael, Meeks, Huong D, Martins, Alexandra, Goldgar, David E, Spurdle, Amanda B

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Lifetime alcohol intake is associated with an increased risk of KRAS+ and BRAF‐/KRAS‐ but not BRAF+ colorectal cancer von Jayasekara, Harindra, MacInnis, Robert J., Williamson, Elizabeth J., Hodge, Allison M., Clendenning, Mark, Rosty, Christophe, Walters, Rhiannon, Room, Robin, Southey, Melissa C., Jenkins, Mark A., Milne, Roger L., Hopper, John L., Giles, Graham G., Buchanan, Daniel D., English, Dallas R.

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Re: Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication von Rosty, Christophe, Williamson, Elizabeth J, Clendenning, Mark, Walters, Rhiannon J, Walsh, Michael D, Win, Aung K, Jenkins, Mark A, Hopper, John L, Winship, Ingrid, Southey, Melissa C, Giles, Graham G, English, Dallas R, Buchanan, Daniel D

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Real-World Applications and Experiences of AI/ML Deployment for Drug Discovery von Pitt, Will R, Bentley, Jonathan, Boldron, Christophe, Colliandre, Lionel, Esposito, Carmen, Frush, Elizabeth H, Kopec, Jola, Labouille, Stéphanie, Meneyrol, Jerome, Pardoe, David A, Palazzesi, Ferruccio, Pozzan, Alfonso, Remington, Jacob M, Rex, René, Southey, Michelle, Vishwakarma, Sachin, Walker, Paul

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Novel Common Genetic Susceptibility Loci for Colorectal Cancer von Schmit, Stephanie L, Edlund, Christopher K, Schumacher, Fredrick R, Gong, Jian, Harrison, Tabitha A, Huyghe, Jeroen R, Qu, Chenxu, Melas, Marilena, Van Den Berg, David J, Wang, Hansong, Tring, Stephanie, Plummer, Sarah J, Albanes, Demetrius, Alonso, M Henar, Amos, Christopher I, Anton, Kristen, Aragaki, Aaron K, Arndt, Volker, Barry, Elizabeth L, Berndt, Sonja I, Bezieau, Stéphane, Bien, Stephanie, Bloomer, Amanda, Boehm, Juergen, Boutron-Ruault, Marie-Christine, Brenner, Hermann, Brezina, Stefanie, Buchanan, Daniel D, Butterbach, Katja, Caan, Bette J, Campbell, Peter T, Carlson, Christopher S, Castelao, Jose E, Chan, Andrew T, Chang-Claude, Jenny, Chanock, Stephen J, Cheng, Iona, Cheng, Ya-Wen, Chin, Lee Soo, Church, James M, Church, Timothy, Coetzee, Gerhard A, Cotterchio, Michelle, Cruz Correa, Marcia, Curtis, Keith R, Duggan, David, Easton, Douglas F, English, Dallas, Feskens, Edith J M, Fischer, Rocky, FitzGerald, Liesel M, Fortini, Barbara K, Fritsche, Lars G, Fuchs, Charles S, Gago-Dominguez, Manuela, Gala, Manish, Gallinger, Steven J, Gauderman, W James, Giles, Graham G, Giovannucci, Edward L, Gogarten, Stephanie M, Gonzalez-Villalpando, Clicerio, Gonzalez-Villalpando, Elena M, Grady, William M, Greenson, Joel K, Gsur, Andrea, Gunter, Marc, Haiman, Christopher A, Hampe, Jochen, Harlid, Sophia, Harju, John F, Hayes, Richard B, Hofer, Philipp, Hoffmeister, Michael, Hopper, John L, Huang, Shu-Chen, Huerta, Jose Maria, Hudson, Thomas J, Hunter, David J, Idos, Gregory E, Iwasaki, Motoki, Jackson, Rebecca D, Jacobs, Eric J, Jee, Sun Ha, Jenkins, Mark A, Jia, Wei-Hua, Jiao, Shuo, Joshi, Amit D, Kolonel, Laurence N, Kono, Suminori, Kooperberg, Charles, Krogh, Vittorio, Kuehn, Tilman, Küry, Sébastien, LaCroix, Andrea, Laurie, Cecelia A, Lejbkowicz, Flavio, Lemire, Mathieu, Lenz, Heinz-Josef, Levine, David

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Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk von Gaudet, Mia M, Kuchenbaecker, Karoline B, Vijai, Joseph, Klein, Robert J, Kirchhoff, Tomas, McGuffog, Lesley, Barrowdale, Daniel, Dunning, Alison M, Lee, Andrew, Dennis, Joe, Healey, Sue, Dicks, Ed, Soucy, Penny, Sinilnikova, Olga M, Pankratz, Vernon S, Wang, Xianshu, Eldridge, Ronald C, Tessier, Daniel C, Vincent, Daniel, Bacot, Francois, Hogervorst, Frans B L, Peock, Susan, Stoppa-Lyonnet, Dominique, Peterlongo, Paolo, Schmutzler, Rita K, Nathanson, Katherine L, Piedmonte, Marion, Singer, Christian F, Thomassen, Mads, Hansen, Thomas v O, Neuhausen, Susan L, Blanco, Ignacio, Greene, Mark H, Garber, Judith, Weitzel, Jeffrey N, Andrulis, Irene L, Goldgar, David E, D'Andrea, Emma, Caldes, Trinidad, Nevanlinna, Heli, Osorio, Ana, van Rensburg, Elizabeth J, Arason, Adalgeir, Rennert, Gad, van den Ouweland, Ans M W, van der Hout, Annemarie H, Kets, Carolien M, Aalfs, Cora M, Wijnen, Juul T, Ausems, Margreet G E M, Frost, Debra, Ellis, Steve, Fineberg, Elena, Platte, Radka, Evans, D Gareth, Jacobs, Chris, Adlard, Julian, Tischkowitz, Marc, Porteous, Mary E, Damiola, Francesca, Golmard, Lisa, Barjhoux, Laure, Longy, Michel, Belotti, Muriel, Ferrer, Sandra Fert, Mazoyer, Sylvie, Spurdle, Amanda B, Manoukian, Siranoush, Barile, Monica, Genuardi, Maurizio, Arnold, Norbert, Meindl, Alfons, Sutter, Christian, Wappenschmidt, Barbara, Domchek, Susan M, Pfeiler, Georg, Friedman, Eitan, Jensen, Uffe Birk, Robson, Mark, Shah, Sohela, Lazaro, Conxi, Mai, Phuong L, Benitez, Javier, Southey, Melissa C, Schmidt, Marjanka K, Fasching, Peter A, Peto, Julian, Humphreys, Manjeet K, Wang, Qin, Michailidou, Kyriaki, Sawyer, Elinor J, Burwinkel, Barbara, Guénel, Pascal, Bojesen, Stig E, Milne, Roger L, Brenner, Hermann, Lochmann, Magdalena, Aittomäki, Kristiina, Dörk, Thilo, Margolin, Sara

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Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study von Howe, Laurence J, Rasheed, Humaira, Jones, Paul R, Boomsma, Dorret I, Evans, David M, Giannelis, Alexandros, Hayward, Caroline, Hopper, John L, Hughes, Amanda, Lahtinen, Hannu, Li, Shuai, Lind, Penelope A, Martin, Nicholas G, Martikainen, Pekka, Medland, Sarah E, Morris, Tim T, Nivard, Michel G, Pingault, Jean-Baptiste, Silventoinen, Karri, Smith, Jennifer A, Willoughby, Emily A, Wilson, James F, Åsvold, Bjørn Olav, Næss, Øyvind E, Davey Smith, George, Kaprio, Jaakko, Brumpton, Ben, Davies, Neil M

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Characterization of a RAD51C -silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance von Hurley, Rachel M, McGehee, Cordelia D, Nesic, Ksenija, Correia, Cristina, Weiskittel, Taylor M, Kelly, Rebecca L, Venkatachalam, Annapoorna, Hou, Xiaonan, Pathoulas, Nicholas M, Meng, X Wei, Kondrashova, Olga, Radke, Marc R, Schneider, Paula A, Flatten, Karen S, Peterson, Kevin L, Becker, Marc A, Wong, Ee Ming, Southey, Melissa S, Dobrovic, Alexander, Lin, Kevin K, Harding, Thomas C, McNeish, Iain, Ross, Christian A, Wagner, Jill M, Wakefield, Matthew J, Scott, Clare L, Haluska, Paul, Wahner Hendrickson, Andrea E, Karnitz, Larry M, Swisher, Elizabeth M, Li, Hu, Weroha, S John, Kaufmann, Scott H

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Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer von Shen, Hui, Fridley, Brooke L., Song, Honglin, Lawrenson, Kate, Cicek, Mine S., Tyrer, Jonathan, Zheng, Wei, Yang, Hannah P., Wozniak, Eva L., Ling Woo, Yin, Winterhoff, Boris, Wentzensen, Nicolas, Palmieri Weber, Rachel, Vitonis, Allison F., Vincent, Daniel, Vierkant, Robert A., Vergote, Ignace, Van Den Berg, David, Van Altena, Anne M., Thompson, Pamela J., Tessier, Daniel C., Terry, Kathryn L., Templeman, Claire, Siddiqui, Nadeem, Shu, Xiao-Ou, Severi, Gianluca, Schwaab, Ira, Salvesen, Helga B., Anne Rossing, Mary, Risch, Harvey A., Renner, Stefan P., Poole, Elizabeth M., Pike, Malcolm C., Phelan, Catherine M., Pelttari, Liisa M., Pejovic, Tanja, Ness, Roberta B., Moysich, Kirsten B., Monteiro, Alvaro N.A., Menon, Usha, Matsuo, Keitaro, Mat Adenan, Noor Azmi, Massuger, Leon F.A.G, Lurie, Galina, Lundvall, Lene, Lubiński, Jan, Lissowska, Jolanta, Levine, Douglas A., Lambrechts, Diether, Kupryjanczyk, Jolanta, Kiemeney, Lambertus A., Karlan, Beth Y., Karevan, Rod, Kalli, Kimberly R., Ji, Bu-Tian, Jakubowska, Anna, Iversen, Edwin, Høgdall, Claus K., Hoatlin, Maureen, Hillemanns, Peter, Halle, Mari K., Hall, Per, Gronwald, Jacek, Gore, Martin, Giles, Graham G., Gentry-Maharaj, Aleksandra, Fasching, Peter A., Ekici, Arif B., Edwards, Robert, Eccles, Diana, Easton, Douglas F., Doherty, Jennifer A., Despierre, Evelyn, Dansonka-Mieszkowska, Agnieszka, Cybulski, Cezary, Cramer, Daniel W., Cook, Linda S., Chen, Xiaoqing, Charbonneau, Bridget, Campbell, Ian, Butzow, Ralf, Bunker, Clareann H., Brueggmann, Doerthe, Brown, Robert, Brooks-Wilson, Angela, Brinton, Louise A., Bogdanova, Natalia, Block, Matthew S., Benjamin, Elizabeth, Beesley, Jonathan, Beckmann, Matthias W., Bandera, Elisa V., Baglietto, Laura, Armasu, Sebastian M., Liang, Dong, Lu, Karen, Hildebrandt, Michelle A.T., Sellers, Thomas A., Laird, Peter W., Leigh Pearce, Celeste

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