Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank von Hollis, B., Chatzigeorgiou, C., Southam, L., Hatzikotoulas, K., Kluzek, S., Williams, A., Zeggini, E., Jostins-Dean, L., Watt, F.E.

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Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants von Southam, L, Soranzo, N, Montgomery, S. B, Frayling, T. M, McCarthy, M. I, Barroso, I, Zeggini, E

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Association analysis of the interleukin 17 genes IL17A and IL17F as potential osteoarthritis susceptibility loci von Southam, L, Heath, O, Chapman, K, Loughlin, J

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Lumbar spine spondylolysis in the adult population: using computed tomography to evaluate the possibility of adult onset lumbar spondylosis as a cause of back pain von Brooks, Benjamin K., Southam, Samuel L., Mlady, Gary W., Logan, Jeremy, Rosett, Matthew

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Improved phenotype definitions of OA in genetic association studies highlight a structural role for a common variant in LRCH1 von Panoutsopoulou, K, Thiagarajah, S, Day-Williams, A.G, Southam, L, Doherty, M, Zeggini, E, Wilkinson, J

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Large-scale genome-wide meta-analyses provide insights for the development of new disease modifying targets for osteoarthritis von Hatzikotoulas, K., Southam, L., Boer, C.G.

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Powerful detection of osteoarthritis susceptibility loci by comprehensive examination of clinically important endophenotypes von Panoutsopoulou, K, Thiagarajah, S, Day-Williams, A, Southam, L, Hatzikotoulas, K, Matchan, A, Doherty, M, Wilkinson, J.M, Zeggini, E

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Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data von Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Southam, Lorraine, Esparza-Gordillo, Jorge, Haberland, Valeriia, Zheng, Jie, Johnson, Toby, Koprulu, Mine, Zengini, Eleni, Steinberg, Julia, Wilkinson, Jeremy M., Bhatnagar, Sahir, Hoffman, Joshua D., Buchan, Natalie, Süveges, Dániel, Yerges-Armstrong, Laura, Smith, George Davey, Gaunt, Tom R., Scott, Robert A., McCarthy, Linda C., Zeggini, Eleftheria

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IDF2022-0368 Integrative analysis of genetic and single-cell omics data reveals cell-types in the pathogenesis of type 2 diabetes von Suzuki, K., Southam, L., Hatzikotoulas, K., Yin, X., Vujkovic, M.

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Lifetime Risk And Genetic Predisposition To Post-Traumatic Osteoarthritis Of The Knee: Time-To-Event And Related Analyses In The Uk Biobank von Hollis, B., Southam, L., Chatzigeorgiou, C., Hatzikotoulas, K., Kluzek, W.S., Williams, A., Zeggini, E., Jostins-Dean, L., Watt, F.E.

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Genetic evidence for a family-based Scandinavian settlement of Shetland and Orkney during the Viking periods von Goodacre, S, Helgason, A, Nicholson, J, Southam, L, Ferguson, L, Hickey, E, Vega, E, Stefánsson, K, Ward, R, Sykes, B

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Effect of different feed formulations on feed efficiency, gonad yield and gonad quality in the purple sea urchin Heliocidaris erythrogramma von Senaratna, M, Evans, L.H, Southam, L, Tsvetnenko, E

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The transferability of lipid loci across African, Asian and European cohorts von Kuchenbaecker, Karoline, Telkar, Nikita, Reiker, Theresa, Walters, Robin G., Lin, Kuang, Eriksson, Anders, Gurdasani, Deepti, Gilly, Arthur, Southam, Lorraine, Tsafantakis, Emmanouil, Karaleftheri, Maria, Seeley, Janet, Kamali, Anatoli, Asiki, Gershim, Millwood, Iona Y., Holmes, Michael, Du, Huaidong, Guo, Yu, Kumari, Meena, Dedoussis, George, Li, Liming, Chen, Zhengming, Sandhu, Manjinder S., Zeggini, Eleftheria

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Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank von Hollis, B, Chatzigeorgiou, C, Southam, L, Hatzikotoulas, K, Kluzek, S, Williams, A, Zeggini, E, Jostins-Dean, L, Watt, FE

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A MOLECULAR MAP OF LONG NON-CODING RNA EXPRESSION, ISOFORM SWITCHING AND ALTERNATIVE SPLICING IN OSTEOARTHRITIS von Katsoula, G., Steinberg, J., Tuerlings, M., Coutinho de Almeida, R., Southam, L., Swift, D., Meulenbelt, I., Wilkinson, J.M., Zeggini, E.

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A comprehensive transcriptional map of knee osteoarthritis von Katsoula, G., Southam, L., Steinberg, J., Barysenka, A., Wilkinson, M.J., Zeggini, E.

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Epigenome-wide association study in knee osteoarthritis generates novel insights into disease mechanisms von Kreitmaier, P., Suderman, M., Southam, L., Steinberg, J., Wilkinson, J.M., Zeggini, E.

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Large-scale transcriptomic analysis reveals new markers of osteoarthritis progression von Katsoula, G., Steinberg, J., Tuerlings, M., Coutinho de Almeida, R., Southam, L., Swift, D., Meulenbelt, I., Wilkinson, J., Zeggini, E.

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Functional Variants within the Secreted Frizzled-Related Protein 3 Gene Are Associated with Hip Osteoarthritis in Females von Loughlin, John, Dowling, Barbara, Chapman, Kay, Marcelline, Lucy, Mustafa, Zehra, Southam, Lorraine, Ferreira, Athena, Ciesielski, Cathleen, Carson, Dennis A., Corr, Maripat

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AN EPIGENOME-WIDE VIEW OF OSTEOARTHRITIS IN PRIMARY TISSUES von Kreitmaier, P., Suderman, M., Southam, L., Coutinho de Almeida, R., Hatzikotoulas, K., Meulenbelt, I., Steinberg, J., Relton, C., Wilkinson, J.M., Zeggini, E.

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