Evaluation of avoralstat, an oral kallikrein inhibitor, in a Phase 3 hereditary angioedema prophylaxis trial: The OPuS‐2 study von Riedl, M. A., Aygören‐Pürsün, E., Baker, J., Farkas, H., Anderson, J., Bernstein, J. A., Bouillet, L., Busse, P., Manning, M., Magerl, M., Gompels, M., Huissoon, A. P., Longhurst, H., Lumry, W., Ritchie, B., Shapiro, R., Soteres, D., Banerji, A., Cancian, M., Johnston, D. T., Craig, T. J., Launay, D., Li, H. H., Liebhaber, M., Nickel, T., Offenberger, J., Rae, W., Schrijvers, R., Triggiani, M., Wedner, H. J., Dobo, S., Cornpropst, M., Clemons, D., Fang, L., Collis, P., Sheridan, W. P., Maurer, M.

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P088 Pharmacokinetics/pharmacodynamics of C1 inhibitor for prevention of angioedema attacks in children with hereditary angioedema (HAE) von Soteres, D, Jacobson, K, Moldovan, D, Christensen, J, Van Leerberghe, A, Wang, Y, Schranz, J, Aygören-Pürsün, E, Martinez-Saguer, I

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Fixed-Dose Subcutaneous C1-Inhibitor Liquid for Prophylactic Treatment of C1-INH-HAE: SAHARA Randomized Study von Lumry, William R., Martinez-Saguer, Inmaculada, Yang, William H., Bernstein, Jonathan A., Jacobs, Joshua, Moldovan, Dumitru, Riedl, Marc A., Johnston, Douglas T., Li, H. Henry, Tang, Yongqiang, Schranz, Jennifer, Lu, Peng, Vardi, Moshe, Farkas, Henriette, Keith, P., Yang, W., Maurer, M., Martinez-Saguer, I., Farkas, H., Reshef, A., Kivity, S., Moldovan, D., Caballero, T., Guilarte, M., Hernandez, M.D., González-Quevedo, M.T., Banerji, A., Bernstein, J., Bewtra, A., Craig, T., Fineman, S., Gower, R., Jacobs, J., Johnston, D., Kashkin, J., Li, H.H., Lumry, W.R., Manning, M., McNeil, D., Melamed, I., Mumneh, N., Nickel, T., Panuto, J., Soteres, D., Tachdjian, R., Offenberger, J., Wedner, J.

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HCP INTEREST IN NASAL EPINEPHRINE SPRAY, A SELF-ADMINISTERED INTRANASAL EPINEPHRINE DEVICE von Chase, N., Burnette, A., Soteres, D., Greiwe, J., Kaplan, H., Kafal, A.

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P045 BEROTRALSTAT DEMONSTRATES LOW HEREDITARY ANGIOEDEMA (HAE) ATTACK RATES IN PATIENTS SWITCHING FROM INJECTABLE PROPHYLAXIS von Riedl, M., Sheridan, W., Noble, L., Tomita, D., Soteres, D.

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BEROTRALSTAT REDUCED ATTACK RATES IN PATIENTS WITH SUSPECTED BRADYKININ-MEDIATED ANGIOEDEMA: REAL-WORLD OUTCOMES von Soteres, D., LiVecchi, M., Nadig, T., Wasilewski, S., Riedl, M., Manning, M., Johnston, D., Noble, L.

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Oral Sebetralstat for On-Demand Treatment of Hereditary Angioedema Attacks von Riedl, Marc A., Farkas, Henriette, Aygören-Pürsün, Emel, Psarros, Fotis, Soteres, Daniel F., Staevska, Maria, Cancian, Mauro, Hagin, David, Honda, Daisuke, Melamed, Isaac, Savic, Sinisa, Stobiecki, Marcin, Busse, Paula J., Dias de Castro, Eunice, Agmon-Levin, Nancy, Gower, Richard, Kessel, Aharon, Kurowski, Marcin, Lleonart, Ramon, Grivcheva Panovska, Vesna, Wedner, H. James, Audhya, Paul K., Hao, James, Iverson, Matthew, Smith, Michael D., Yea, Christopher M., Lumry, William R., Zanichelli, Andrea, Bernstein, Jonathan A., Maurer, Marcus, Cohn, Danny M.

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LONG-TERM PROPHYLACTIC TREATMENT PREFERENCES OF PATIENTS WITH HEREDITARY ANGIOEDEMA von Hahn, R., Soteres, D., Olson, C., Ray, T., Lopez-Gonzalez, L., Gillard, P., Nestler-Parr, S., Poulos, C., Lionetti, M.

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DIAGNOSTIC PATHWAYS IN LANADELUMAB-TREATED PATIENTS WITH NORMAL C1-INHIBITOR HEREDITARY ANGIOEDEMA (NC1-INH-HAE): A MULTICENTER CHART REVIEW von Bernstein, J., Kanarek, H., Soteres, D., Mutschelknaus, D., Cala, M., Schultz, B., Juethner, S., Young, L.

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REAL-WORLD QUALITY OF LIFE IN PATIENTS WITH HAE RECEIVING LANADELUMAB OR OTHER LONG-TERM PROPHYLAXIS von Davis-Lorton, M., Soteres, D., Lumry, W., Hall, J., Connolly, H., Fox, D., Schultz, B., Juethner, S.

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REAL-WORLD OUTCOMES IN PATIENTS WITH HAE RECEIVING LANADELUMAB LONG-TERM PROPHYLAXIS FOR 3 YEARS OR LONGER von Lumry, W., Davis-Lorton, M., Soteres, D., Earl, L., Wynne-Cattanach, K., Sing, K., Juethner, S., Schultz, B.

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Do shrimp-allergic individuals tolerate shrimp-derived glucosamine? von Villacis, J., Rice, T. R., Bucci, L. R., El-Dahr, J. M., Wild, L., DeMerell, D., Soteres, D., Lehrer, S. B.

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PHYSICIAN AND PATIENT REPORTED OUTCOMES BY HEREDITARY ANGIOEDEMA TYPE: DATA FROM A REAL-WORLD STUDY von Anderson, J., Soteres, D., Mellor, J., Connolly, H., Wynne-Cattanach, K., Earl, L., Schultz, B., Juethner, S.

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Long‐term prevention of hereditary angioedema attacks with lanadelumab: The HELP OLE Study von Banerji, Aleena, Bernstein, Jonathan A., Johnston, Douglas T., Lumry, William R., Magerl, Markus, Maurer, Marcus, Martinez‐Saguer, Inmaculada, Zanichelli, Andrea, Hao, James, Inhaber, Neil, Yu, Ming, Riedl, Marc A., Hébert, J., Ritchie, B., Sussman, G., Yang, W.H., Aygören‐Pürsün, E., Magerl, M., Martinez‐Saguer, I., Staubach, P., Cicardi, M., Shennak, M., Zaragoza‐Urdaz, R.H., Kiani‐Alikhan, S., Anderson, J., Banerji, A., Baptist, A.P., Bernstein, J.A., Busse, P.J., Craig, T., Davis‐Lorton, M., Gierer, S., Gower, R.G., Harris, D., Jacobs, J., Johnston, D.T., Li, H.H., Lockey, R.F., Lugar, P., Lumry, W.R., Manning, M.E., McNeil, D.L., Melamed, I., Otto, W.R., Rehman, S.M., Riedl, M.A., Schwartz, L.B., Shapiro, R., Sher, E., Smith, A.M., Soteres, D., Tachdjian, R., Wedner, H.J., Weinstein, M.E., Zafra, H.

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P163 QUALITY OF LIFE OF HEREDITARY ANGIOEDEMA (HAE) PATIENTS WITH DEPRESSION OR ANXIETY RECEIVING LANADELUMAB von Craig, T., Soteres, D., Anderson, J., Paes, K., Hao, J., Hashemi, L., Watt, M., Juethner, S.

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Impact of lanadelumab on health‐related quality of life in patients with hereditary angioedema in the HELP study von Lumry, William R., Weller, Karsten, Magerl, Markus, Banerji, Aleena, Longhurst, Hilary J., Riedl, Marc A., Lewis, Hannah B., Lu, Peng, Devercelli, Giovanna, Jain, Gagan, Maurer, Marcus, Hébert, J, Ritchie, B, Sussman, G, Yang, WH, Martinez‐Saguer, I, Staubach, P, Cicardi, M, Shennak, M, Zaragoza‐Urdaz, RH, Anderson, J, Baptist, AP, Bernstein, JA, Boggs, PB, Busse, PJ, Craig, T, Davis‐Lorton, M, Gierer, S, Gower, RG, Harris, D, Hong, DI, Jacobs, J, Johnston, DT, Li, HH, Lockey, RF, Lugar, P, Manning, ME, McNeil, DL, Melamed, I, Mostofi, T, Nickel, T, Otto, WR, Petrov, AA, Radojicic, C, Rehman, SM, Schwartz, LB, Shapiro, R, Sher, E, Smith, AM, Soteres, D, Tachdjian, R, Wedner, HJ, Weinstein, ME, Zafra, H

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P154 BEROTRALSTAT IMPROVES PATIENT-REPORTED QUALITY OF LIFE THROUGH 48 WEEKS IN THE PHASE 3 APEX-2 TRIAL von Johnston, D., Banerji, A., Riedl, M., Soteres, D., Bernstein, J., Best, J., Iocca, H., Murray, S., Lumry, W.

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Preventing Hereditary Angioedema Attacks in Children Using Cinryze®: Interim Efficacy and Safety Phase 3 Findings von Aygören-Pürsün, Emel, Soteres, Daniel, Moldovan, Dumitru, Christensen, Jim, Van Leerberghe, Arthur, Hao, James, Schranz, Jennifer, Jacobson, Kraig W., Martinez-Saguer, Inmaculada

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Lanadelumab demonstrates rapid and sustained prevention of hereditary angioedema attacks von Riedl, Marc A., Maurer, Marcus, Bernstein, Jonathan A., Banerji, Aleena, Longhurst, Hilary J., Li, H. Henry, Lu, Peng, Hao, James, Juethner, Salomé, Lumry, William R., Hébert, J, Ritchie, B, Sussman, G, Yang, WH, Escuriola Ettingshausen, C, Magerl, M, Martinez‐Saguer, I, Maurer, M, Staubach, P, Zimmer, S, Cicardi, M, Perego, F, Wu, MA, Zanichelli, A, Al‐Ghazawi, A, Shennak, M, Zaragoza‐Urdaz, RH, Ghurye, R, Longhurst, HJ, Zinser, E, Anderson, J, Banerji, A, Baptist, AP, Bernstein, JA, Boggs, PB, Busse, PJ, Christiansen, S, Craig, T, Davis‐Lorton, M, Gierer, S, Gower, RG, Harris, D, Hong, DI, Jacobs, J, Johnston, DT, Levitch, ES, Li, HH, Lockey, RF, Lugar, P, Lumry, WR, Manning, ME, McNeil, DL, Melamed, I, Mostofi, T, Nickel, T, Otto, WR, Petrov, AA, Poarch, K, Radojicic, C, Rehman, SM, Riedl, MA, Schwartz, LB, Shapiro, R, Sher, E, Smith, AM, Smith, TD, Soteres, D, Tachdjian, R, Wedner, HJ, Weinstein, ME, Zafra, H, Zuraw, BL

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C1 INHIBITOR ADMINISTRATION IN PEDIATRIC PATIENTS WITH HEREDITARY ANGIOEDEMA: PATIENT COMPLIANCE WITH INTRAVENOUS THERAPY von Jacobson, K., Soteres, D., Nieto-Martinez, S., Moldovan, D., Martinez-Saguer, I., Vardi, M., Baptista, J., Aygoren-Pursun, E.

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