A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 von Zhou, Yadi, Hou, Yuan, Shen, Jiayu, Mehra, Reena, Kallianpur, Asha, Culver, Daniel A, Gack, Michaela U, Farha, Samar, Zein, Joe, Comhair, Suzy, Fiocchi, Claudio, Stappenbeck, Thaddeus, Chan, Timothy, Eng, Charis, Jung, Jae U, Jehi, Lara, Erzurum, Serpil, Cheng, Feixiong

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A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases von Zeighami, Yashar, Bakken, Trygve E, Nickl-Jockschat, Thomas, Peterson, Zeru, Jegga, Anil G, Miller, Jeremy A, Schulkin, Jay, Evans, Alan C, Lein, Ed S, Hawrylycz, Michael

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Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content von Liang, Xiaomin, Yee, Sook Wah, Chien, Huan-Chieh, Chen, Eugene C, Luo, Qi, Zou, Ling, Piao, Meiling, Mifune, Arias, Chen, Ligong, Calvert, Meredith E, King, Sarah, Norheim, Frode, Abad, Janna, Krauss, Ronald M, Giacomini, Kathleen M

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Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants von Laddach, Anna, Ng, Joseph Chi Fung, Fraternali, Franca

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Multivariate phenotype analysis enables genome-wide inference of mammalian gene function von Nicholson, George, Morgan, Hugh, Ganjgahi, Habib, Brown, Steve D M, Mallon, Ann-Marie, Holmes, Chris

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Low-complexity bound on irregular LDPC belief-propagation decoding thresholds using a Gaussian approximation von Vatta, F, Soranzo, A, Babich, F

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New explicitly invertible approximation of the function involved in LDPC codes density evolution analysis using a Gaussian approximation von Vatta, F, Soranzo, A, Comisso, M, Buttazzoni, G, Babich, F

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The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update von Afgan, Enis, Nekrutenko, Anton, Grüning, Bjórn A, Blankenberg, Daniel, Goecks, Jeremy, Schatz, Michael C, Ostrovsky, Alexander E, Mahmoud, Alexandru, Lonie, Andrew J, Syme, Anna, Fouilloux, Anne, Bretaudeau, Anthony, Kumar, Anup, Eschenlauer, Arthur C, DeSanto, Assunta D, Guerler, Aysam, Serrano-Solano, Beatriz, Batut, Bérénice, Grüning, Björn A, Langhorst, Bradley W, Carr, Bridget, Raubenolt, Bryan A, Hyde, Cameron J, Bromhead, Catherine J, Barnett, Christopher B, Royaux, Coline, Gallardo, Cristóbal, Fornika, Daniel J, Baker, Dannon, Bouvier, Dave, Clements, Dave, de Lima Morais, David A, Tabernero, David Lopez, Lariviere, Delphine, Nasr, Engy, Zambelli, Federico, Heyl, Florian, Psomopoulos, Fotis, Coppens, Frederik, Price, Gareth R, Cuccuru, Gianmauro, Corguillé, Gildas Le, Von Kuster, Greg, Akbulut, Gulsum Gudukbay, Rasche, Helena, Hotz, Hans-Rudolf, Eguinoa, Ignacio, Makunin, Igor, Ranawaka, Isuru J, Taylor, James P, Joshi, Jayadev, Hillman-Jackson, Jennifer, Chilton, John M, Kamali, Kaivan, Suderman, Keith, Poterlowicz, Krzysztof, Yvan, Le Bras, Lopez-Delisle, Lucille, Sargent, Luke, Bassetti, Madeline E, Tangaro, Marco Antonio, van den Beek, Marius, Čech, Martin, Bernt, Matthias, Fahrner, Matthias, Tekman, Mehmet, Föll, Melanie C, Crusoe, Michael R, Roncoroni, Miguel, Kucher, Natalie, Coraor, Nate, Stoler, Nicholas, Rhodes, Nick, Soranzo, Nicola, Pinter, Niko, Goonasekera, Nuwan A, Moreno, Pablo A, Videm, Pavankumar, Melanie, Petera, Mandreoli, Pietro, Jagtap, Pratik D, Gu, Qiang, Weber, Ralf J M, Lazarus, Ross, Vorderman, Ruben H P, Hiltemann, Saskia, Golitsynskiy, Sergey, Garg, Shilpa, Bray, Simon A, Gladman, Simon L, Leo, Simone, Mehta, Subina P, Griffin, Timothy J, Jalili, Vahid, Yves, Vandenbrouck, Wen, Victor, Nagampalli, Vijay K, Bacon, Wendi A, de Koning, Willem, Maier, Wolfgang

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Global validity of the Master kinetic equation for hard-sphere systems von Tessarotto, M., Cremaschini, C., Asci, C., Soranzo, A., Tironi, G.

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Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements von Grundberg, Elin, Meduri, Eshwar, Sandling, Johanna K., Hedman, Åsa K., Keildson, Sarah, Buil, Alfonso, Busche, Stephan, Yuan, Wei, Nisbet, James, Sekowska, Magdalena, Wilk, Alicja, Barrett, Amy, Small, Kerrin S., Ge, Bing, Caron, Maxime, Shin, So-Youn, Ahmadi, Kourosh R., Ainali, Chrysanthi, Barrett, Amy, Bataille, Veronique, Bell, Jordana T., Buil, Alfonso, Deloukas, Panos, Dermitzakis, Emmanouil T., Dimas, Antigone S., Durbin, Richard, Glass, Daniel, Grundberg, Elin, Hassanali, Neelam, Hedman, Åsa K., Ingle, Catherine, Knowles, David, Krestyaninova, Maria, Lindgren, Cecilia M., Lowe, Christopher E., McCarthy, Mark I., Meduri, Eshwar, di Meglio, Paola, Min, Josine L., Montgomery, Stephen B., Nestle, Frank O., Nica, Alexandra C., Nisbet, James, O’Rahilly, Stephen, Parts, Leopold, Potter, Simon, Sandling, Johanna, Sekowska, Magdalena, Shin, So-Youn, Small, Kerrin S., Soranzo, Nicole, Spector, Tim D., Surdulescu, Gabriela, Travers, Mary E., Tsaprouni, Loukia, Tsoka, Sophia, Wilk, Alicja, Yang, Tsun-Po, Zondervan, Krina T., Lathrop, Mark, Dermitzakis, Emmanouil T., McCarthy, Mark I., Spector, Timothy D., Bell, Jordana T., Deloukas, Panos

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Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status von Lyons, Paul A, Peters, James E, Alberici, Federico, Liley, James, Coulson, Richard M. R., Astle, William, Baldini, Chiara, Bonatti, Francesco, Cid, Maria C, Elding, Heather, Emmi, Giacomo, Epplen, Jörg, Guillevin, Loïc, Jayne, David R. W., Jiang, Tao, Gunnarsson, Iva, Lamprecht, Peter, Leslie, Stephen, Little, Mark A., Martorana, Davide, Moosig, Frank, Neumann, Thomas, Ohlsson, Sophie, Quickert, Stefanie, Ramirez, Giuseppe A., Rewerska, Barbara, Schett, Georg, Sinico, Renato A., Szczeklik, Wojciech, Tesar, Vladimir, Vukcevic, Damjan, Terrier, Benjamin, Watts, Richard A, Vaglio, Augusto, Holle, Julia U, Wallace, Chris, Smith, Kenneth G. C.

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The UK10K project identifies rare variants in health and disease von Walter, Klaudia, Min, Josine L, Huang, Jie, Crooks, Lucy, Memari, Yasin, McCarthy, Shane, Perry, John R B, Xu, ChangJiang, Futema, Marta, Lawson, Daniel, Iotchkova, Valentina, Schiffels, Stephan, Hendricks, Audrey E, Danecek, Petr, Li, Rui, Floyd, James, Wain, Louise V, Barroso, Inês, Humphries, Steve E, Hurles, Matthew E, Zeggini, Eleftheria, Barrett, Jeffrey C, Plagnol, Vincent, Richards, J Brent, Greenwood, Celia M T, Timpson, Nicholas J, Durbin, Richard, Soranzo, Nicole

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Lightness constancy: Ratio invariance and luminance profile von Soranzo, Alessandro, Galmonte, Alessandra, Agostini, Tiziano

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Timing, rates and spectra of human germline mutation von Rahbari, Raheleh, Wuster, Arthur, Lindsay, Sarah J, Hardwick, Robert J, Alexandrov, Ludmil B, Al Turki, Saeed, Dominiczak, Anna, Morris, Andrew, Porteous, David, Smith, Blair, Stratton, Michael R, Hurles, Matthew E

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Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling von Logan, Clare V, Szabadkai, György, Sharpe, Jenny A, Parry, David A, Torelli, Silvia, Childs, Anne-Marie, Kriek, Marjolein, Phadke, Rahul, Johnson, Colin A, Roberts, Nicola Y, Bonthron, David T, Pysden, Karen A, Whyte, Tamieka, Munteanu, Iulia, Foley, A Reghan, Wheway, Gabrielle, Szymanska, Katarzyna, Natarajan, Subaashini, Abdelhamed, Zakia A, Morgan, Joanne E, Roper, Helen, Santen, Gijs W E, Niks, Erik H, van der Pol, W Ludo, Lindhout, Dick, Raffaello, Anna, De Stefani, Diego, den Dunnen, Johan T, Sun, Yu, Ginjaar, Ieke, Sewry, Caroline A, Hurles, Matthew, Rizzuto, Rosario, Duchen, Michael R, Muntoni, Francesco, Sheridan, Eamonn

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Wisdom of crowds for robust gene network inference von Marbach, Daniel, Costello, James C, Küffner, Robert, Vega, Nicole M, Prill, Robert J, Camacho, Diogo M, Allison, Kyle R, Kellis, Manolis, Collins, James J, Stolovitzky, Gustavo

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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function von Hawe, Johann S., Wilson, Rory, Schmid, Katharina T., Zhou, Li, Lakshmanan, Lakshmi Narayanan, Lehne, Benjamin C., Kühnel, Brigitte, Scott, William R., Wielscher, Matthias, Yew, Yik Weng, Baumbach, Clemens, Lee, Dominic P., Marouli, Eirini, Bernard, Manon, Pfeiffer, Liliane, Matías-García, Pamela R., Autio, Matias I., Bourgeois, Stephane, Herder, Christian, Karhunen, Ville, Meitinger, Thomas, Prokisch, Holger, Rathmann, Wolfgang, Roden, Michael, Sebert, Sylvain, Shin, Jean, Strauch, Konstantin, Zhang, Weihua, Tan, Wilson L. W., Hauck, Stefanie M., Merl-Pham, Juliane, Grallert, Harald, Barbosa, Eudes G. V., Illig, Thomas, Peters, Annette, Paus, Tomas, Pausova, Zdenka, Deloukas, Panos, Foo, Roger S. Y., Jarvelin, Marjo-Riitta, Kooner, Jaspal S., Loh, Marie, Heinig, Matthias, Gieger, Christian, Waldenberger, Melanie, Chambers, John C.

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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population von Bell, Jordana T, Tsai, Pei-Chien, Yang, Tsun-Po, Pidsley, Ruth, Nisbet, James, Glass, Daniel, Mangino, Massimo, Zhai, Guangju, Zhang, Feng, Valdes, Ana, Shin, So-Youn, Dempster, Emma L, Murray, Robin M, Grundberg, Elin, Hedman, Asa K, Nica, Alexandra, Small, Kerrin S, Dermitzakis, Emmanouil T, McCarthy, Mark I, Mill, Jonathan, Spector, Tim D, Deloukas, Panos

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A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance von Hivert, Marie-France, Scott, Robert A, Grimsby, Jonna L, Chen, Han, Amin, Najaf, Barnes, Daniel, Cadby, Gemma, Hottenga, Jouke-Jan, Ingelsson, Erik, Kanoni, Stavroula, Ladenvall, Claes, Lagou, Vasiliki, Liu, Yongmei, Martinez-Larrad, Maria Teresa, Navarro, Pau, Strawbridge, Rona J, Tanaka, Toshiko, de Andrade, Mariza, Aulchenko, Yurii, Balkau, Beverley, Beilby, John P, Blangero, John, Boban, Mladen, Boomsma, Dorret I, Böttcher, Yvonne, Bouchard, Claude, Budimir, Danijela, Clarke, Robert, Corbatón-Anchuelo, Arturo, Couper, David, Dedoussis, George V, Erdos, Michael R, Eriksson, Johan G, Franzosi, Maria Grazia, Franks, Paul W, Galan, Pilar, de Geus, Eco, Hallmans, Göran, Hansson, Ola, Harris, Tamara B, Hayward, Caroline, Hingorani, Aroon, Johnson, Paul C D, Jukema, J Wouter, Jula, Antti, Kolcic, Ivana, Kumari, Meena, Lakka, Timo, Lannfelt, Lars, Lathrop, G Mark, Lind, Lars, Lobbens, Stéphane, Loos, Ruth J F, Lyssenko, Valeriya, Magnusson, Patrik K E, Marmot, Michael, Meneton, Pierre, Mooser, Vincent, Morken, Mario A, Ong, Ken K, Oostra, Ben A, Palmer, Lyle J, Palotie, Aarno, Peden, John F, Pedersen, Nancy L, Penninx, Brenda, Perola, Markus, Peyser, Patricia A, Räikkönen, Katri, Rehnberg, Emil, Rotter, Jerome I, Rudan, Igor, Ruokonen, Aimo, Saaristo, Timo, Sabater-Lleal, Maria, Salomaa, Veikko, Saxena, Richa, Sennblad, Bengt, Shuldiner, Alan R, Sijbrands, Eric J G, Small, Kerrin S, Smith, Nicholas L, Sun, Yan V, Tuomilehto, Jaakko, Uitterlinden, Andre G, Vikström, Max, Vitart, Veronique, Vohl, Marie-Claude, Voight, Benjamin F, Waeber, Gerard, Wheeler, Eleanor, Widen, Elisabeth, Willemsen, Gonneke, Wilson, James F, Witteman, Jacqueline C M, Yaghootkar, Hanieh, Barroso, Ines, Watanabe, Richard M, Florez, Jose C, Meigs, James B

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Gene expression changes with age in skin, adipose tissue, blood and brain von Glass, Daniel, Viñuela, Ana, Davies, Matthew N, Ramasamy, Adaikalavan, Parts, Leopold, Knowles, David, Brown, Andrew A, Hedman, Asa K, Small, Kerrin S, Buil, Alfonso, Grundberg, Elin, Nica, Alexandra C, Di Meglio, Paola, Nestle, Frank O, Ryten, Mina, Durbin, Richard, McCarthy, Mark I, Deloukas, Panagiotis, Dermitzakis, Emmanouil T, Weale, Michael E, Bataille, Veronique, Spector, Tim D

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