Identification of Novel Therapeutic Targets for Polyglutamine Diseases That Target Mitochondrial Fragmentation von Traa, Annika, Machiela, Emily, Rudich, Paige D, Soo, Sonja K, Senchuk, Megan M, Van Raamsdonk, Jeremy M

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Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants von Harris-Gauthier, Namastheé, Traa, Annika, AlOkda, Abdelrahman, Moldakozhayev, Alibek, Anglas, Ulrich, Soo, Sonja K., Van Raamsdonk, Jeremy M.

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Biological resilience and aging: Activation of stress response pathways contributes to lifespan extension von Soo, Sonja K., Rudich, Zenith D., Ko, Bokang, Moldakozhayev, Alibek, AlOkda, Abdelrahman, Van Raamsdonk, Jeremy M.

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Genetic basis of enhanced stress resistance in long‐lived mutants highlights key role of innate immunity in determining longevity von Soo, Sonja K., Traa, Annika, Rudich, Zenith D., Moldakozhayev, Alibek, Mistry, Meeta, Van Raamsdonk, Jeremy M.

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Mild mitochondrial impairment enhances innate immunity and longevity through ATFS-1 and p38 signaling von Campos, Juliane C, Wu, Ziyun, Rudich, Paige D, Soo, Sonja K, Mistry, Meeta, Ferreira, Julio CB, Blackwell, T Keith, Van Raamsdonk, Jeremy M

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Endosomal trafficking protein TBC‐2 modulates stress resistance and lifespan through DAF‐16‐dependent and independent mechanisms von Traa, Annika, Soo, Sonja K., AlOkda, Abdelrahman, Ko, Bokang, Rocheleau, Christian E., Van Raamsdonk, Jeremy M.

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Compounds that extend longevity are protective in neurodegenerative diseases and provide a novel treatment strategy for these devastating disorders von Soo, Sonja K., Rudich, Paige D., Traa, Annika, Harris-Gauthier, Namasthée, Shields, Hazel J., Van Raamsdonk, Jeremy M.

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Targeting Mitochondrial Network Disorganization is Protective in C. elegans Models of Huntington’s Disease von Machiela, Emily, Rudich, Paige D, Traa, Annika, Anglas, Ulrich, Soo, Sonja K, Senchuk, Megan M, Van Raamsdonk, Jeremy M

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Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors von Soo, Sonja K, Traa, Annika, Rudich, Paige D, Mistry, Meeta, Van Raamsdonk, Jeremy M

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High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture von Robert, Jérôme, Button, Emily B, Stukas, Sophie, Boyce, Guilaine K, Gibbs, Ebrima, Cowan, Catherine M, Gilmour, Megan, Cheng, Wai Hang, Soo, Sonja K, Yuen, Brian, Bahrabadi, Arvin, Kang, Kevin, Kulic, Iva, Francis, Gordon, Cashman, Neil, Wellington, Cheryl L

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High confidence ATFS-1 target genes for quantifying activation of the mitochondrial unfolded protein response von Soo, Sonja K, Van Raamsdonk, Jeremy M

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A Novel Approach for Assessing Visual Impairment Caused by Intraocular Lens Opacification: High-Resolution Optical Coherence Tomography von Yildirim, Timur M., Łabuz, Grzegorz, Hammer, Maximilian, Son, Hyeck-Soo, Schickhardt, Sonja K., Auffarth, Gerd U., Khoramnia, Ramin

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Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer von Ross, L., Eisen, A., Elsafy, F., Fielding, A., Friedman, S., Gianni, L., Phillips, K.-A., Singer, C.F., Toi, M., Park, Y.H., Yang, H., Mailliez, A., Nagy, T., Sonke, G.S., Sun, Q., Colleoni, M.A., Kaufman, B., Cameron, D., Campbell, C., Sevelda, Paul, Öhler, Leopold, Rumpold, Holger, Rautenberg, Beate, Boadle, David, Mackey, John, Niraula, Saroj, Randal d’Hondt, Papadimitriou, Konstantinos, Lazzaro, Mauricio Fernández, Pilnik, Norma, Varela, Mirta, Darsow, Maren, Park-Simon, Tjoung-Won, Terhaag, Jürgen, Salat, Christoph, Dieterich, Max, García Sáenz, José Ángel, Lanza, Angels Arcusa, Quiroga, Vanesa, Jañez, Noelia Martínez, Crusades, Gema Llort, Rodríguez, César, Cretella, Elisabetta, Jegannathen, Apurna, Ishida, Kazushige, Watanabe, Junichiro, Takada, Masahiro, Nakamura, Seigo, Aogi, Kenjiro, Tsugawa, Koichiro, Seaward, Samantha A., Carney, Jennifer Fu, Bobolis, Kristie A., Eisenberg, Peter D., Hofstatter, Erin W., McCarron, Edward C., Herbolsheimer, Pia, Meisel, Jane L., Jones, Cheryl F., Spector, David M., Lo, Shelly S., Cristofanilli, Massimo, Hahn, Olwen M., Oliff, Ira A., Ansari, Bilal, Sharma, Priyanka, Armstrong, Deborah K., VanderWoude, Amy, Friday, Bret E.B., T, Benjamin, Kuzma, Charles S., Radford, James E., Soori, Gamini S., Vogel, Victor G., Wilkinson, Mary, Qamar, Rubina, Loman, Niklas, Silander, Gustav, Abreu, Miguel, Ciruelos Gil, Eva María, Bermejo de las Heras, Begoña, Busch, Steffi, Thomalla, Jörg, Altena, Renske, Chen, Shou-Tung, Huang, Chiun-Sheng, Yeh, Dah-Cherng, Pottier, Virginie, Yang, Hongjian, Fu, Peifen, Wang, Yongsheng, Fan, Zhimin, Landherr, László, Yerushalmi, Rinat, Conte, Pierfranco, Ciccarese, Mariangela, Mackiewicz, Jacek, Kalinka, Ewa, Im, Seock-Ah, Lee, Kyoung Eun

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Material Analysis of Explanted Calcified Silicone Intraocular Lenses in Association with Asteroid Hyalosis von Chychko, Lizaveta, Khoramnia, Ramin, Son, Hyeck-Soo, Schickhardt, Sonja K., Lieberwirth, Ingo, Auffarth, Gerd U., Yildirim, Timur M.

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Variation in intraocular lens calcification under different environmental conditions in eyes with supplementary sulcus-supported lenses von Yildirim, Timur M., Khoramnia, Ramin, Schickhardt, Sonja K., Munro, Donald J., Merz, Patrick R., Son, Hyeck-Soo, Lieberwirth, Ingo, Auffarth, Gerd U.

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Isolation and characterization of canine perivascular stem/stromal cells for bone tissue engineering von James, Aaron W, Zhang, Xinli, Crisan, Mihaela, Hardy, Winters R, Liang, Pei, Meyers, Carolyn A, Lobo, Sonja, Lagishetty, Venu, Childers, Martin K, Asatrian, Greg, Ding, Catherine, Yen, Yu-Hsin, Zou, Erin, Ting, Kang, Peault, Bruno, Soo, Chia

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Quantification of the In Vitro Predisposition to Glistening Formation in One Manufacturer’s Acrylic Intraocular Lenses Made in Different Decades von Wang, Qiang, Yildirim, Timur M., Schickhardt, Sonja K., Łabuz, Grzegorz, Khoramnia, Ramin, Merz, Patrick R., Son, Hyeck-Soo, Munro, Donald J., Friedmann, Elfriede, Auffarth, Gerd U.

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Abstract 574: High-Density Lipoproteins Suppress Amyloid Beta Induced Human Brain Microvascular Endothelial Cell Activation von Button, Emily B, Robert, Jerome, Stukus, Sophie K, Boyce, Guilaine, Gibbs, Ebrima, Cowan, Catherine, Cheng, Wai Hang, Soo, Sonja, Yuen, Brian, Kang, Kevin, Bahrabadi, Arvin, Kulic, Iva, Francis, Gordon, Cashman, Neil, Wellington, Cheryl L

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Quantification of the In-Vitro Predisposition to Glistening Formation in One Manufacturer’s Acrylic Intraocular Lenses Made in Different Decades von Adis journals on behalf of, Wang, Qiang, Yildirim, Timur M., Schickhardt, Sonja K., Łabuz, Grzegorz, Khoramnia, Ramin, Merz, Patrick R., Son, Hyeck-Soo, Munro, Donald J., Friedmann, Elfriede, Auffarth, Gerd U.

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DOC-2/hDab-2 inhibits ILK activity and induces anoikis in breast cancer cells through an Akt-independent pathway von WANG, Shao-Chun, MAKINO, Keishi, WEIYA XIA, JEONG SOO KIM, IM, Seock-Ah, HUA PENG, MOK, Samuel C, SINGLETARY, Sonja E, HUNG, Mien-Chie

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