Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl‐Chain Length and Hepatic Insulin Sensitivity in Mice von Matsuzaka, Takashi, Kuba, Motoko, Koyasu, Saori, Yamamoto, Yuta, Motomura, Kaori, Arulmozhiraja, Sundaram, Ohno, Hiroshi, Sharma, Rahul, Shimura, Takuya, Okajima, Yuka, Han, Song‐iee, Aita, Yuichi, Mizunoe, Yuhei, Osaki, Yoshinori, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sone, Hirohito, Takeuchi, Yoshinori, Yahagi, Naoya, Miyamoto, Takafumi, Sekiya, Motohiro, Nakagawa, Yoshimi, Ema, Masatsugu, Takahashi, Satoru, Tokiwa, Hiroaki, Shimano, Hitoshi

Volltext

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice von Araki, Masaya, Nakagawa, Yoshimi, Oishi, Asayo, Han, Song-Iee, Wang, Yunong, Kumagai, Kae, Ohno, Hiroshi, Mizunoe, Yuhei, Iwasaki, Hitoshi, Sekiya, Motohiro, Matsuzaka, Takashi, Shimano, Hitoshi

Volltext

Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity von Saito, Kenji, Sekiya, Motohiro, Kainoh, Kenta, Yoshino, Ryunosuke, Hayashi, Akio, Han, Song-Iee, Araki, Masaya, Ohno, Hiroshi, Takeuchi, Yoshinori, Tsuyuzaki, Tomomi, Yamazaki, Daichi, Wanpei, Chen, Hada, Lisa, Watanabe, Sho, Paramita Adi Putri, Putu Indah, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi

Volltext

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism von Sharma, Rahul, Matsuzaka, Takashi, Kaushik, Mahesh K., Sugasawa, Takehito, Ohno, Hiroshi, Wang, Yunong, Motomura, Kaori, Shimura, Takuya, Okajima, Yuka, Mizunoe, Yuhei, Ma, Yang, Saber, Zahara M., Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Aita, Yuichi, Han, Song-iee, Takeuchi, Yoshinori, Yahagi, Naoya, Miyamoto, Takafumi, Sekiya, Motohiro, Nakagawa, Yoshimi, Shimano, Hitoshi

Volltext

Starvation‐induced transcription factor CREBH negatively governs body growth by controlling GH signaling von Nakagawa, Yoshimi, Kumagai, Kae, Han, Song‐iee, Mizunoe, Yuhei, Araki, Masaya, Mizuno, Seiya, Ohno, Hiroshi, Matsuo, Kazuya, Yamada, Yasunari, Kim, Jun‐dal, Miyamoto, Takafumi, Sekiya, Motohiro, Konishi, Morichika, Itoh, Nobuyuki, Matsuzaka, Takashi, Takahashi, Satoru, Sone, Hirohito, Shimano, Hitoshi

Volltext

Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease von Araki, Masaya, Nakagawa, Yoshimi, Saito, Hodaka, Yamada, Yasunari, Han, Song-Iee, Mizunoe, Yuhei, Ohno, Hiroshi, Miyamoto, Takafumi, Sekiya, Motohiro, Matsuzaka, Takashi, Sone, Hirohito, Shimano, Hitoshi

Volltext

CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions von Nakagawa, Yoshimi, Araki, Masaya, Han, Song-iee, Mizunoe, Yuhei, Shimano, Hitoshi

Volltext

Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice von Takei, Kenta, Nakagawa, Yoshimi, Wang, Yunong, Han, Song-iee, Satoh, Aoi, Sekiya, Motohiro, Matsuzaka, Takashi, Shimano, Hitoshi

Volltext

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα von Nakagawa, Yoshimi, Satoh, Aoi, Tezuka, Hitomi, Han, Song-iee, Takei, Kenta, Iwasaki, Hitoshi, Yatoh, Shigeru, Yahagi, Naoya, Suzuki, Hiroaki, Iwasaki, Yasumasa, Sone, Hirohito, Matsuzaka, Takashi, Yamada, Nobuhiro, Shimano, Hitoshi

Volltext

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice von Suzuki-Kemuriyama, Noriko, Matsuzaka, Takashi, Kuba, Motoko, Ohno, Hiroshi, Han, Song-Iee, Takeuchi, Yoshinori, Isaka, Masaaki, Kobayashi, Kazuto, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Miyajima, Katsuhiro, Nakae, Dai, Yahagi, Naoya, Nakagawa, Yoshimi, Sone, Hirohito, Yamada, Nobuhiro, Shimano, Hitoshi

Volltext

Selective peroxisome proliferator‐activated receptor‐α modulator K‐877 efficiently activates the peroxisome proliferator‐activated receptor‐α pathway and improves lipid metabolism... von Takei, Kenta, Han, Song‐iee, Murayama, Yuki, Satoh, Aoi, Oikawa, Fusaka, Ohno, Hiroshi, Osaki, Yoshinori, Matsuzaka, Takashi, Sekiya, Motohiro, Iwasaki, Hitoshi, Yatoh, Shigeru, Yahagi, Naoya, Suzuki, Hiroaki, Yamada, Nobuhiro, Nakagawa, Yoshimi, Shimano, Hitoshi

Volltext

Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice von Okajima, Yuka, Matsuzaka, Takashi, Miyazaki, Shun, Motomura, Kaori, Ohno, Hiroshi, Sharma, Rahul, Shimura, Takuya, Istiqamah, Nurani, Han, Song-iee, Mizunoe, Yuhei, Osaki, Yoshinori, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sone, Hirohito, Miyamoto, Takafumi, Aita, Yuichi, Takeuchi, Yoshinori, Sekiya, Motohiro, Yahagi, Naoya, Nakagawa, Yoshimi, Tomita, Tsutomu, Shimano, Hitoshi

Volltext

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance von Ohno, Hiroshi, Matsuzaka, Takashi, Tang, Nie, Sharma, Rahul, Motomura, Kaori, Shimura, Takuya, Satoh, Aoi, Han, Song-iee, Takeuchi, Yoshinori, Aita, Yuichi, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sekiya, Motohiro, Nakagawa, Yoshimi, Sone, Hirohito, Yahagi, Naoya, Yamada, Nobuhiro, Higami, Yoshikazu, Shimano, Hitoshi

Volltext

Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM) von Miyamoto, Takafumi, Han, Song-Iee, Shimano, Hitoshi

Volltext

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system von Nakagawa, Yoshimi, Oikawa, Fusaka, Mizuno, Seiya, Ohno, Hiroshi, Yagishita, Yuka, Satoh, Aoi, Osaki, Yoshinori, Takei, Kenta, Kikuchi, Takuya, Han, Song-iee, Matsuzaka, Takashi, Iwasaki, Hitoshi, Kobayashi, Kazuto, Yatoh, Shigeru, Yahagi, Naoya, Isaka, Masaaki, Suzuki, Hiroaki, Sone, Hirohito, Takahashi, Satoru, Yamada, Nobuhiro, Shimano, Hitoshi

Volltext

Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice von Han, SI, Komatsu, Y, Murayama, A, Steffensen, KR, Nakagawa, Y, Nakajima, Y, Suzuki, M, Oie, S, Parini, P, Vedin, LL, Kishimoto, H, Shimano, H, Gustafsson, JA, Yanagisawa, J

Volltext

MafA Stability in Pancreatic β Cells Is Regulated by Glucose and Is Dependent on Its Constitutive Phosphorylation at Multiple Sites by Glycogen Synthase Kinase 3 von Han, Song-iee, Aramata, Shinsaku, Yasuda, Kunio, Kataoka, Kohsuke

Volltext

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression von Kikuchi, Takuya, Orihara, Kana, Oikawa, Fusaka, Han, Song-iee, Kuba, Motoko, Okuda, Kanako, Satoh, Aoi, Osaki, Yoshinori, Takeuchi, Yoshinori, Aita, Yuichi, Matsuzaka, Takashi, Iwasaki, Hitoshi, Yatoh, Shigeru, Sekiya, Motohiro, Yahagi, Naoya, Suzuki, Hiroaki, Sone, Hirohito, Nakagawa, Yoshimi, Yamada, Nobuhiro, Shimano, Hitoshi

Volltext

Identification of key microRNAs regulating ELOVL6 and glioblastoma tumorigenesis von Istiqamah, Nurani, Matsuzaka, Takashi, Shimizu, Momo, Motomura, Kaori, Ohno, Hiroshi, Hasebe, Shiho, Sharma, Rahul, Okajima, Yuka, Matsuda, Erika, Han, Song-Iee, Mizunoe, Yuhei, Osaki, Yoshinori, Aita, Yuichi, Suzuki, Hiroaki, Sone, Hirohito, Takeuchi, Yoshinori, Sekiya, Motohiro, Yahagi, Naoya, Nakagawa, Yoshimi, Shimano, Hitoshi

Volltext

Gata3 cooperates with Gcm2 and MafB to activate parathyroid hormone gene expression by interacting with SP1 von Han, Song-iee, Tsunekage, Yukino, Kataoka, Kohsuke

Volltext