Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy von Li, Xin, Song, Yongcheng

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Structure, function and inhibition of critical protein-protein interactions involving mixed lineage leukemia 1 and its fusion oncoproteins von Li, Xin, Song, Yongcheng

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Regioselective Radical Aminofluorination of Styrenes von Zhang, Hongwei, Song, Yongcheng, Zhao, Jinbo, Zhang, Jingping, Zhang, Qian

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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives von Song, Yongcheng, Wu, Fangrui, Wu, Jingyu

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A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth von Li, Xin, Yao, Yuan, Wu, Fangrui, Song, Yongcheng

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DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy von Liu, Wei, Deng, Lisheng, Song, Yongcheng, Redell, Michele

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A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L von Anglin, Justin L, Song, Yongcheng

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3‑(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1 von Wu, Fangrui, Zhou, Chao, Yao, Yuan, Wei, Liping, Feng, Zizhen, Deng, Lisheng, Song, Yongcheng

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An epigenomic approach to therapy for tamoxifen-resistant breast cancer von Feng, Qin, Zhang, Zheng, Shea, Martin J, Creighton, Chad J, Coarfa, Cristian, Hilsenbeck, Susan G, Lanz, Rainer, He, Bin, Wang, Lei, Fu, Xiaoyong, Nardone, Agostina, Song, Yongcheng, Bradner, James, Mitsiades, Nicholas, Mitsiades, Constantine S, Osborne, C Kent, Schiff, Rachel, O'Malley, Bert W

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Thermodynamic investigation of DNA-binding affinity of wild-type and mutant transcription factor RUNX1 von Wu, Fangrui, Song, Tidie, Yao, Yuan, Song, Yongcheng

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Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review von Li, Xin, Song, Yongcheng

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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2‑Thiohydantoin Compounds von Wu, Fangrui, Jiang, Hong, Zheng, Baisong, Kogiso, Mari, Yao, Yuan, Zhou, Chao, Li, Xiao-Nan, Song, Yongcheng

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Characterization of sea buckthorn polysaccharides and the analysis of its regulatory effect on the gut microbiota imbalance induced by cefixime in mice von Xie, Xinyao, Song, Yongcheng, Bi, Xiufang, Liu, Xiaocui, Xing, Yage, Che, Zhenming

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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia von Rau, Rachel E., Rodriguez, Benjamin A., Luo, Min, Jeong, Mira, Rosen, Allison, Rogers, Jason H., Campbell, Carly T., Daigle, Scott R., Deng, Lishing, Song, Yongcheng, Sweet, Steve, Chevassut, Timothy, Andreeff, Michael, Kornblau, Steven M., Li, Wei, Goodell, Margaret A.

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Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies von Yao, Yuan, Chen, Pinhong, Diao, Jiasheng, Cheng, Gang, Deng, Lisheng, Anglin, Justin L, Prasad, B. V. Venkataram, Song, Yongcheng

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Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence von Liu, Chia -I, Liu, George Y, Song, Yongcheng, Yin, Fenglin, Hensler, Mary E, Jeng, Wen-Yih, Nizet, Victor, Wang, Andrew H.-J, Oldfield, Eric

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Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma von Bharadwaj, Uddalak, Eckols, T Kris, Xu, Xuejun, Kasembeli, Moses M, Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y, Tweardy, David J

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Targeting SARS-CoV-2 nonstructural protein 3: Function, structure, inhibition, and perspective in drug discovery von Li, Xin, Song, Yongcheng

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Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia von Feng, Zizhen, Yao, Yuan, Zhou, Chao, Chen, Fengju, Wu, Fangrui, Wei, Liping, Liu, Wei, Dong, Shuo, Redell, Michele, Mo, Qianxing, Song, Yongcheng

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Perspective for Drug Discovery Targeting SARS Coronavirus Methyltransferases: Function, Structure and Inhibition von Li, Xin, Song, Yongcheng

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