Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics von Morita, Kiyomi, Wang, Feng, Jahn, Katharina, Hu, Tianyuan, Tanaka, Tomoyuki, Sasaki, Yuya, Kuipers, Jack, Loghavi, Sanam, Wang, Sa A., Yan, Yuanqing, Furudate, Ken, Matthews, Jairo, Little, Latasha, Gumbs, Curtis, Zhang, Jianhua, Song, Xingzhi, Thompson, Erika, Patel, Keyur P., Bueso-Ramos, Carlos E., DiNardo, Courtney D., Ravandi, Farhad, Jabbour, Elias, Andreeff, Michael, Cortes, Jorge, Bhalla, Kapil, Garcia-Manero, Guillermo, Kantarjian, Hagop, Konopleva, Marina, Nakada, Daisuke, Navin, Nicholas, Beerenwinkel, Niko, Futreal, P. Andrew, Takahashi, Koichi

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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia von Wang, Feng, Morita, Kiyomi, DiNardo, Courtney D., Furudate, Ken, Tanaka, Tomoyuki, Yan, Yuanqing, Patel, Keyur P., MacBeth, Kyle J., Wu, Bin, Liu, Guowen, Frattini, Mark, Matthews, Jairo A., Little, Latasha D., Gumbs, Curtis, Song, Xingzhi, Zhang, Jianhua, Thompson, Erika J., Kadia, Tapan M., Garcia-Manero, Guillermo, Jabbour, Elias, Ravandi, Farhad, Bhalla, Kapil N., Konopleva, Marina, Kantarjian, Hagop M., Andrew Futreal, P., Takahashi, Koichi

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Systematic analysis of telomere length and somatic alterations in 31 cancer types von Barthel, Floris P, Wei, Wei, Tang, Ming, Martinez-Ledesma, Emmanuel, Hu, Xin, Amin, Samirkumar B, Akdemir, Kadir C, Seth, Sahil, Song, Xingzhi, Wang, Qianghu, Lichtenberg, Tara, Hu, Jian, Zhang, Jianhua, Zheng, Siyuan, Verhaak, Roel G W

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Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma von Wang, Ruiping, Dang, Minghao, Harada, Kazuto, Han, Guangchun, Wang, Fang, Pool Pizzi, Melissa, Zhao, Meina, Tatlonghari, Ghia, Zhang, Shaojun, Hao, Dapeng, Lu, Yang, Zhao, Shuangtao, Badgwell, Brian D., Blum Murphy, Mariela, Shanbhag, Namita, Estrella, Jeannelyn S., Roy-Chowdhuri, Sinchita, Abdelhakeem, Ahmed Adel Fouad, Wang, Yuanxin, Peng, Guang, Hanash, Samir, Calin, George A., Song, Xingzhi, Chu, Yanshuo, Zhang, Jianhua, Li, Mingyao, Chen, Ken, Lazar, Alexander J., Futreal, Andrew, Song, Shumei, Ajani, Jaffer A., Wang, Linghua

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A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations von Zhang, Yiqun, Kwok-Shing Ng, Patrick, Kucherlapati, Melanie, Chen, Fengju, Liu, Yuexin, Tsang, Yiu Huen, de Velasco, Guillermo, Jeong, Kang Jin, Akbani, Rehan, Hadjipanayis, Angela, Pantazi, Angeliki, Bristow, Christopher A., Lee, Eunjung, Mahadeshwar, Harshad S., Tang, Jiabin, Zhang, Jianhua, Yang, Lixing, Seth, Sahil, Lee, Semin, Ren, Xiaojia, Song, Xingzhi, Sun, Huandong, Seidman, Jonathan, Luquette, Lovelace J., Xi, Ruibin, Chin, Lynda, Protopopov, Alexei, Westbrook, Thomas F., Shelley, Carl Simon, Choueiri, Toni K., Ittmann, Michael, Van Waes, Carter, Weinstein, John N., Liang, Han, Henske, Elizabeth P., Godwin, Andrew K., Park, Peter J., Kucherlapati, Raju, Scott, Kenneth L., Mills, Gordon B., Kwiatkowski, David J., Creighton, Chad J.

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Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing von Zhang, Jianjun, Fujimoto, Junya, Zhang, Jianhua, Wedge, David C., Song, Xingzhi, Zhang, Jiexin, Seth, Sahil, Chow, Chi-Wan, Cao, Yu, Gumbs, Curtis, Gold, Kathryn A., Kalhor, Neda, Little, Latasha, Mahadeshwar, Harshad, Moran, Cesar, Protopopov, Alexei, Sun, Huandong, Tang, Jiabin, Wu, Xifeng, Ye, Yuanqing, William, William N., Lee, J. Jack, Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Futreal, P. Andrew

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Comprehensive T cell repertoire characterization of non-small cell lung cancer von Reuben, Alexandre, Zhang, Jiexin, Chiou, Shin-Heng, Gittelman, Rachel M., Li, Jun, Lee, Won-Chul, Fujimoto, Junya, Behrens, Carmen, Liu, Xiaoke, Wang, Feng, Quek, Kelly, Wang, Chunlin, Kheradmand, Farrah, Chen, Runzhe, Chow, Chi-Wan, Lin, Heather, Bernatchez, Chantale, Jalali, Ali, Hu, Xin, Wu, Chang-Jiun, Eterovic, Agda Karina, Parra, Edwin Roger, Yusko, Erik, Emerson, Ryan, Benzeno, Sharon, Vignali, Marissa, Wu, Xifeng, Ye, Yuanqing, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Cascone, Tina, Snyder, Alexandra, Wargo, Jennifer A., Herbst, Roy, Swisher, Stephen, Kadara, Humam, Moran, Cesar, Kalhor, Neda, Zhang, Jianhua, Scheet, Paul, Vaporciyan, Ara A., Sepesi, Boris, Gibbons, Don L., Robins, Harlan, Hwu, Patrick, Heymach, John V., Sharma, Padmanee, Allison, James P., Baladandayuthapani, Veera, Lee, Jack J., Davis, Mark M., Wistuba, Ignacio I., Futreal, P. Andrew, Zhang, Jianjun

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Clearance of Somatic Mutations at Remission and the Risk of Relapse in Acute Myeloid Leukemia von Morita, Kiyomi, Kantarjian, Hagop M, Wang, Feng, Yan, Yuanqing, Bueso-Ramos, Carlos, Sasaki, Koji, Issa, Ghayas C, Wang, Sa, Jorgensen, Jeffrey, Song, Xingzhi, Zhang, Jianhua, Tippen, Samantha, Thornton, Rebecca, Coyle, Marcus, Little, Latasha, Gumbs, Curtis, Pemmaraju, Naveen, Daver, Naval, DiNardo, Courtney D, Konopleva, Marina, Andreeff, Michael, Ravandi, Farhad, Cortes, Jorge E, Kadia, Tapan, Jabbour, Elias, Garcia-Manero, Guillermo, Patel, Keyur P, Futreal, P Andrew, Takahashi, Koichi

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Oncogenic Kras drives invasion and maintains metastases in colorectal cancer von Boutin, Adam T, Liao, Wen-Ting, Wang, Melody, Hwang, Soyoon Sarah, Karpinets, Tatiana V, Cheung, Hannah, Chu, Gerald C, Jiang, Shan, Hu, Jian, Chang, Kyle, Vilar, Eduardo, Song, Xingzhi, Zhang, Jianhua, Kopetz, Scott, Futreal, Andrew, Wang, Y Alan, Kwong, Lawrence N, DePinho, Ronald A

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Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets von Ferrarotto, Renata, Mitani, Yoshitsugu, McGrail, Daniel J., Li, Kaiyi, Karpinets, Tatiana, Bell, Diana, Frank, Steven J., Song, Xingzhi, Kupferman, Michael E., Liu, Bin, Lee, J. Jack, Glisson, Bonnie S., Zhang, Jianhua, Aster, Jon C., Lin, Shiaw-Yih, Futreal, P. Andrew, Heymach, John, El-Naggar, Adel K.

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Recurrent PTPRB and PLCG1 mutations in angiosarcoma von Behjati, Sam, Tarpey, Patrick S, Sheldon, Helen, Martincorena, Inigo, Van Loo, Peter, Gundem, Gunes, Wedge, David C, Ramakrishna, Manasa, Cooke, Susanna L, Pillay, Nischalan, Vollan, Hans Kristian M, Papaemmanuil, Elli, Koss, Hans, Bunney, Tom D, Hardy, Claire, Joseph, Olivia R, Martin, Sancha, Mudie, Laura, Butler, Adam, Teague, Jon W, Patil, Meena, Steers, Graham, Cao, Yu, Gumbs, Curtis, Ingram, Davis, Lazar, Alexander J, Little, Latasha, Mahadeshwar, Harshad, Protopopov, Alexei, Al Sannaa, Ghadah A, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Zhang, Jianhua, Ravi, Vinod, Torres, Keila E, Khatri, Bhavisha, Halai, Dina, Roxanis, Ioannis, Baumhoer, Daniel, Tirabosco, Roberto, Amary, M Fernanda, Boshoff, Chris, McDermott, Ultan, Katan, Matilda, Stratton, Michael R, Futreal, P Andrew, Flanagan, Adrienne M, Harris, Adrian, Campbell, Peter J

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Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma von Hu, Xin, Fujimoto, Junya, Ying, Lisha, Fukuoka, Junya, Ashizawa, Kazuto, Sun, Wenyong, Reuben, Alexandre, Chow, Chi-Wan, McGranahan, Nicholas, Chen, Runzhe, Hu, Jinlin, Godoy, Myrna C., Tabata, Kazuhiro, Kuroda, Kishio, Shi, Lei, Li, Jun, Behrens, Carmen, Parra, Edwin Roger, Little, Latasha D., Gumbs, Curtis, Mao, Xizeng, Song, Xingzhi, Tippen, Samantha, Thornton, Rebecca L., Kadara, Humam, Scheet, Paul, Roarty, Emily, Ostrin, Edwin Justin, Wang, Xu, Carter, Brett W., Antonoff, Mara B., Zhang, Jianhua, Vaporciyan, Ara A., Pass, Harvey, Swisher, Stephen G., Heymach, John V., Lee, J. Jack, Wistuba, Ignacio I., Hong, Waun Ki, Futreal, P. Andrew, Su, Dan, Zhang, Jianjun

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The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics von Tang, Ming, Abbas, Hussein A., Negrao, Marcelo V., Ramineni, Maheshwari, Hu, Xin, Hubert, Shawna Marie, Fujimoto, Junya, Reuben, Alexandre, Varghese, Susan, Zhang, Jianhua, Li, Jun, Chow, Chi-Wan, Mao, Xizeng, Song, Xingzhi, Lee, Won-Chul, Wu, Jia, Little, Latasha, Gumbs, Curtis, Behrens, Carmen, Moran, Cesar, Weissferdt, Annikka, Lee, J. Jack, Sepesi, Boris, Swisher, Stephen, Cheng, Chao, Kurie, Jonathan, Gibbons, Don, Heymach, John V., Wistuba, Ignacio I., Futreal, P. Andrew, Kalhor, Neda, Zhang, Jianjun

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Mechanisms of nuclear content loading to exosomes von Yokoi, Akira, Villar-Prados, Alejandro, Oliphint, Paul Allen, Zhang, Jianhua, Song, Xingzhi, De Hoff, Peter, Morey, Robert, Liu, Jinsong, Roszik, Jason, Clise-Dwyer, Karen, Burks, Jared K, O'Halloran, Theresa J, Laurent, Louise C, Sood, Anil K

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Genomic heterogeneity of multiple synchronous lung cancer von Liu, Yu, Zhang, Jianjun, Li, Lin, Yin, Guangliang, Zhang, Jianhua, Zheng, Shan, Cheung, Hannah, Wu, Ning, Lu, Ning, Mao, Xizeng, Yang, Longhai, Zhang, Jiexin, Zhang, Li, Seth, Sahil, Chen, Huang, Song, Xingzhi, Liu, Kan, Xie, Yongqiang, Zhou, Lina, Zhao, Chuanduo, Han, Naijun, Chen, Wenting, Zhang, Susu, Chen, Longyun, Cai, Wenjun, Li, Lin, Shen, Miaozhong, Xu, Ningzhi, Cheng, Shujun, Yang, Huanming, Lee, J. Jack, Correa, Arlene, Fujimoto, Junya, Behrens, Carmen, Chow, Chi-Wan, William, William N., Heymach, John V., Hong, Waun Ki, Swisher, Stephen, Wistuba, Ignacio I., Wang, Jun, Lin, Dongmei, Liu, Xiangyang, Futreal, P. Andrew, Gao, Yanning

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Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma von Zhang, Shaojun, Jiang, Vivian Changying, Han, Guangchun, Hao, Dapeng, Lian, Junwei, Liu, Yang, Cai, Qingsong, Zhang, Rongjia, McIntosh, Joseph, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Wang, Yuanxin, Santos, David, Badillo, Maria, Leeming, Angela, Chen, Zhihong, Hartig, Kimberly, Bigcal, John, Zhou, Jia, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Lee, Hun, Steiner, Raphael E., Zhang, Jianhua, Song, Xingzhi, Nair, Ranjit, Ahmed, Sairah, Rodriquez, Alma, Thirumurthi, Selvi, Jain, Preetesh, Wagner-Bartak, Nicolaus, Hill, Holly, Nomie, Krystle, Flowers, Christopher, Futreal, Andrew, Wang, Linghua, Wang, Michael

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Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis von Fukumura, Kazutaka, Malgulwar, Prit Benny, Fischer, Grant M., Hu, Xiaoding, Mao, Xizeng, Song, Xingzhi, Hernandez, Sharia D., Zhang, Xiang H.-F., Zhang, Jianhua, Parra, Edwin Roger, Yu, Dihua, Debeb, Bisrat G., Davies, Michael A., Huse, Jason T.

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Direct selection of human genomic loci by microarray hybridization von Albert, Thomas J, Gibbs, Richard A, Molla, Michael N, Muzny, Donna M, Nazareth, Lynne, Wheeler, David, Song, Xingzhi, Richmond, Todd A, Middle, Chris M, Rodesch, Matthew J, Packard, Charles J, Weinstock, George M

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Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer von Lee, Sanghoon, Zhao, Li, Rojas, Christine, Bateman, Nicholas W., Yao, Hui, Lara, Olivia D., Celestino, Joseph, Morgan, Margaret B., Nguyen, Tri V., Conrads, Kelly A., Rangel, Kelly M., Dood, Robert L., Hajek, Richard A., Fawcett, Gloria L., Chu, Randy A., Wilson, Katlin, Loffredo, Jeremy L., Viollet, Coralie, Jazaeri, Amir A., Dalgard, Clifton L., Mao, Xizeng, Song, Xingzhi, Zhou, Ming, Hood, Brian L., Banskota, Nirad, Wilkerson, Matthew D., Te, Jerez, Soltis, Anthony R., Roman, Kristin, Dunn, Andrew, Cordover, David, Eterovic, Agda Karina, Liu, Jinsong, Burks, Jared K., Baggerly, Keith A., Fleming, Nicole D., Lu, Karen H., Westin, Shannon N., Coleman, Robert L., Mills, Gordon B., Casablanca, Yovanni, Zhang, Jianhua, Conrads, Thomas P., Maxwell, George L., Futreal, P. Andrew, Sood, Anil K.

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Global impact of somatic structural variation on the DNA methylome of human cancers von Zhang, Yiqun, Yang, Lixing, Kucherlapati, Melanie, Hadjipanayis, Angela, Pantazi, Angeliki, Bristow, Christopher A, Lee, Eunjung Alice, Mahadeshwar, Harshad S, Tang, Jiabin, Zhang, Jianhua, Seth, Sahil, Lee, Semin, Ren, Xiaojia, Song, Xingzhi, Sun, Huandong, Seidman, Jonathan, Luquette, Lovelace J, Xi, Ruibin, Chin, Lynda, Protopopov, Alexei, Park, Peter J, Kucherlapati, Raju, Creighton, Chad J

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