Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127 von Montoya, Skye, Bourcier, Jessie, Noviski, Mark, Lu, Hao, Thompson, Meghan C, Chirino, Alexandra, Jahn, Jacob, Sondhi, Anya K, Gajewski, Stefan, Tan, Ying Siow May, Yung, Stephanie, Urban, Aleksandra, Wang, Eric, Han, Cuijuan, Mi, Xiaoli, Kim, Won Jun, Sievers, Quinlan, Auger, Paul, Bousquet, Hugo, Brathaban, Nivetha, Bravo, Brandon, Gessner, Melissa, Guiducci, Cristiana, Iuliano, James N, Kane, Tim, Mukerji, Ratul, Reddy, Panga Jaipal, Powers, Janine, Sanchez Garcia de Los Rios, Mateo, Ye, Jordan, Barrientos Risso, Carla, Tsai, Daniel, Pardo, Gabriel, Notti, Ryan Q, Pardo, Alejandro, Affer, Maurizio, Nawaratne, Vindhya, Totiger, Tulasigeri M, Pena-Velasquez, Camila, Rhodes, Joanna M, Zelenetz, Andrew D, Alencar, Alvaro, Roeker, Lindsey E, Mehta, Sanjoy, Garippa, Ralph, Linley, Adam, Soni, Rajesh Kumar, Skånland, Sigrid S, Brown, Robert J, Mato, Anthony R, Hansen, Gwenn M, Abdel-Wahab, Omar, Taylor, Justin

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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition von Chaudhry, Sana, Beckedorff, Felipe, Jasdanwala, Shaista Shabbir, Totiger, Tulasigeri M., Affer, Maurizio, Lawal, Abimbola Eunice, Montoya, Skye, Tamiro, Francesco, Tonini, Olivia, Chirino, Alexandra, Adams, Andrew, Sondhi, Anya K., Noudali, Stephen, Cornista, Alyssa Mauri, Nicholls, Miah, Afaghani, Jumana, Robayo, Paola, Bilbao, Daniel, Nimer, Stephen D., Rodríguez, Jose Antonio, Bhatt, Shruti, Wang, Eric, Taylor, Justin

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A big STEP (Simultaneous Tumor and Effector Profiling) forward in the battle against chimeric antigen receptor (CAR) T-cell therapy resistance von Sondhi, Anya K, Risso, Carla Barrientos, Taylor, Justin

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Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development von Hmila, Issam, Hill, Jaunetta, Shalaby, Karim E., Ouararhni, Khalid, Abedsselem, Houari, Modaresi, Seyed Mohamad Sadegh, Bihaqi, Syed Waseem, Marques, Emily, Sondhi, Anya, Slitt, Angela L., Zawia, Nasser H.

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Targeted Therapy Development in Acute Myeloid Leukemia von Totiger, Tulasigeri M, Ghoshal, Anirban, Zabroski, Jenna, Sondhi, Anya, Bucha, Saanvi, Jahn, Jacob, Feng, Yangbo, Taylor, Justin

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Abstract P23: RHOA inactivation subverts IFN-γ response and promotes antigen escape in CAR-T resistant diffuse large B-cell lymphoma von Newsam, Austin D, Coughlin, Caroline A, Goretsky, Yitzhar E, Alaoui, Abdessumad Y, Tsai, Daniel E, Coffey, David G, Sondhi, Anya K, Roberts, Evan R, Gallego, Natalia Campos, Manara, Paola, Bilbao, Daniel, Ziccheddu, Bachisio, Spiegel, Jay Y, Jain, Michael D, Locke, Frederick L, Alderuccio, Juan P, Maura, Francesco, Schatz, Jonathan H

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