Molecular Recipe for γ‑Secretase Modulation from Computational Analysis of 60 Active Compounds von Tang, Ning, Somavarapu, Arun K, Kepp, Kasper P

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A computer-simulated mechanism of familial Alzheimer’s disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase von Dehury, Budheswar, Somavarapu, Arun K., Kepp, Kasper P.

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Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein-Evidence for a common hot spot site at the interface and its functional relevance von Nanaware, Padma P., Ramteke, Manoj P., Somavarapu, Arun K., Venkatraman, Prasanna

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The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+–Aβ Complex von Somavarapu, Arun K., Shen, Fei, Teilum, Kaare, Zhang, Jingdong, Mossin, Susanne, Thulstrup, Peter W., Bjerrum, Morten J., Tiwari, Manish K., Szunyogh, Daniel, Søtofte, Peter M., Kepp, Kasper P., Hemmingsen, Lars

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The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu 2+ -Aβ Complex von Somavarapu, Arun K, Shen, Fei, Teilum, Kaare, Zhang, Jingdong, Mossin, Susanne, Thulstrup, Peter W, Bjerrum, Morten J, Tiwari, Manish K, Szunyogh, Daniel, Søtofte, Peter M, Kepp, Kasper P, Hemmingsen, Lars

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The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+-A[beta] Complex von Somavarapu, Arun K, Shen, Fei, Teilum, Kaare, Zhang, Jingdong, Mossin, Susanne, Thulstrup, Peter W, Bjerrum, Morten J, Tiwari, Manish K, Szunyogh, Daniel, Sotofte, Peter M, Kepp, Kasper P, Hemmingsen, Lars

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